Click here to switch to the map view.

The map label for this gene is acdA [H]

Identifier: 52142424

GI number: 52142424

Start: 2931485

End: 2932633

Strand: Reverse

Name: acdA [H]

Synonym: BCZK2818

Alternate gene names: 52142424

Gene position: 2932633-2931485 (Counterclockwise)

Preceding gene: 52142423

Following gene: 52142425

Centisome position: 55.32

GC content: 40.3

Gene sequence:

>1149_bases
ATGGCACTCTCATTTGTTGAAACAGAAAAACAATCTTTCATTATTGAACAAATAAATAAATTGATTCCGAAGTTCATGGA
AAGGGAGCATCAACTAAGTGAATTAGGATCATTTCCGTATGAAAATATAAATGATTTAAAAGATATCGGATATACGAAAT
TAACGTTACCGAAGGAATTTGGTGGTAGTGCGATTTCTTTATATGACTTCGTTTTATTTCAAGAGAAAATTGCGGAAGGC
TGCGGAGCTACTGCATTATCGATTGGCTGGCATCTTGGTATTGTGAAAGAGCTGGCGGAAAATCGTTCTTGGAATGATGA
GATGTTCAAATGGTTTTGCGAAGAAGTTCGTAATGGAGCGCTCTTTAACAGGGCAGCAACAGAACCGAAAACAGGGAGCC
CGACGCGTGGCGGTAAACCAGAAACAATAGCGGTTCAACAAGGCGAGAAGTGGGTTATAAATGGAAGGAAAACTTTTACA
ACGATGGCGCCAGTACTTGATTATTTTATTATTTCAGCAAGTATGGAAGGCCAAGAAGAAGTTGGTGAGTTTGTCATTCC
AAGAAATACACTCGGTGTATCCATTGAAGAAACGTGGGATAGCGTTGCAATGCGAGGGACTGCTAGCCACGACCTTGTCT
TACAAAATGTAGAGATAGACAACCGCTTTTTTACGGATGTAAAAGGCGGGAAAGTGAAACAAAAGGGTATTGGCTGGTTG
CTACATATACCAGCATGTTATTTAGGAATTGCACAATCAGCAAGAAATTATGCAGTTCAGTTTGCGGGATCATACAAGCC
AAATAGTTTAAACCATTCTATTAGTTTATTACCGAATGTTAGAAGATTAGTTGGAGAATTAGAACTCGAGCTTATGCAAG
CTCGCGTCTTTTTATATCAAATTGCGAAAAAATACGATGAGGCAGAAGATAAACTGTCACTGCAAGCAGAATTAGCGGCA
GTGAAATACGCCGTAACAAATGCGGCGATATCCATAGTGGATAAATCAATGCGCATCGTAGGAGCAAAAAGTTTATCAGA
AAAAAATCCGCTTCACCGTTACTATTTAAACGTCAGAGCAGGACTACACAATCCGCCGATGGACGATGCAACACTGTCTA
TGCTTGCGGATGCGGCGTTTCGATCGTAG

Upstream 100 bases:

>100_bases
TGTATTTTTATCGGAATAGTGAAACAATAGAGAGGTAGCTTCATATAATCATAATGACAAAATGAACGGTTCATGAATCG
AACATAAAGGAGATTATAGT

Downstream 100 bases:

>100_bases
GTTTTTTAACTTGAATTTTATTGTTTATGGACAATATAGTTGTTTTGAAAGCACGTGTTTGATTAGTAATCGAACACGTG
CTTTTTATGTACAGGAACGT

Product: acyl-CoA dehydrogenase, short-chain specific

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEFGGSAISLYDFVLFQEKIAEG
CGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGALFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFT
TMAPVLDYFIISASMEGQEEVGEFVIPRNTLGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQIAKKYDEAEDKLSLQAELAA
VKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDATLSMLADAAFRS

Sequences:

>Translated_382_residues
MALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEFGGSAISLYDFVLFQEKIAEG
CGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGALFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFT
TMAPVLDYFIISASMEGQEEVGEFVIPRNTLGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQIAKKYDEAEDKLSLQAELAA
VKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDATLSMLADAAFRS
>Mature_381_residues
ALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEFGGSAISLYDFVLFQEKIAEGC
GATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGALFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFTT
MAPVLDYFIISASMEGQEEVGEFVIPRNTLGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWLL
HIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQIAKKYDEAEDKLSLQAELAAV
KYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDATLSMLADAAFRS

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=332, Percent_Identity=22.8915662650602, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI226958412, Length=351, Percent_Identity=21.9373219373219, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI226958414, Length=324, Percent_Identity=21.6049382716049, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=318, Percent_Identity=24.5283018867925, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=358, Percent_Identity=20.9497206703911, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=315, Percent_Identity=20.952380952381, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=343, Percent_Identity=23.3236151603499, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24646207, Length=349, Percent_Identity=24.3553008595989, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355753, Length=319, Percent_Identity=23.1974921630094, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24666513, Length=353, Percent_Identity=22.9461756373938, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42698; Mature: 42567

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCHHH
GGSAISLYDFVLFQEKIAEGCGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
LFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFTTMAPVLDYFIISASMEGQEE
EECCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
VGEFVIPRNTLGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
HCCEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCEEECCCCCCEEECCCCCEE
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQ
EEHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKKYDEAEDKLSLQAELAAVKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
GLHNPPMDDATLSMLADAAFRS
CCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCHHH
GGSAISLYDFVLFQEKIAEGCGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
LFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFTTMAPVLDYFIISASMEGQEE
EECCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
VGEFVIPRNTLGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
HCCEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCEEECCCCCCEEECCCCCEE
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQ
EEHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKKYDEAEDKLSLQAELAAVKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
GLHNPPMDDATLSMLADAAFRS
CCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]