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The map label for this gene is kat [H]

Identifier: 52142377

GI number: 52142377

Start: 2993175

End: 2994815

Strand: Reverse

Name: kat [H]

Synonym: BCZK2865

Alternate gene names: 52142377

Gene position: 2994815-2993175 (Counterclockwise)

Preceding gene: 52142375

Following gene: 52142378

Centisome position: 56.5

GC content: 40.65

Gene sequence:

>1641_bases
ATGGAAGAAAACCAGGACATGAATTCTCTAGATGAACAAGACGTGAAACGTGAGACATTGACAACACGACAGGGGCACCC
TGTGAAGGATAATCAAAATATCCGAACAATTGGGAATCGTGGTCCAGCAACACTTGAAAATTATCATTTCATCGAAAAAA
TTTCTCATTTTGATCGAGAAGAGGTTCCGGAACGTGTAGTACATGCGCGAGGAGCTGGAGCATTTGGGTATTTTGAGACC
TATGGAAAAGTTGGAGATGAGCCGGTAGAAAAATATACTCGTGCGAAAGTATTTTCAGGGGCTGGTAAAAAAACGCCGTT
AATGGTTCGTTTTTCTACAGTAGCTGGAGCCAAGGACTCACCAGAAACAGCAAGGGATCCACGAGGTTTTGCAGTGAAAA
TGTATACGGAAGATGGTAACTGGGATTTAGTAGGGAATAATTTAAAAATTTTCTTTATTCGTGATGCGATGAAGTTCCCA
GATATGATTCATGCGTTTAAGGTTGATCCGGTTTCGAATGTAGCGAATCCTCAGAGAATGTTTGATTTTGTTTCTCGTAC
CCCGGAGGCAACGCATATGATTACATTTTTATTTTCTCCATGGGGTATTCCAGCAACATATCGCCATATGCAGGGATCTG
GTGTAAACACTTATAAATGGGTAAATGAAAAAGGCGAAGCGGTATTGGTGAAATATCACTGGGAGCCGAAGCAGGGAATT
CGAAATTTAACACAAGAAGATGCAAACAGTATTCAAGCAATGAATGTTAGTCATGCAACACAAGATTTATATGAGGCAAT
TGAGCGCAAAGATTATCCAGAGTGGGAGCTATTTGTACAAATTATGGAGGATGATTATCATCCAGAACTCGATTTTGATC
CTCTTGATGATACGAAGCTTTGGCCAGAGGAGCAGTTCCCCTGGTTACCAGTAGGGCGTATGGTTCTTGATCGTAATCCA
GTTGATTACCATTCAGACATTGAACAAGCTGCTTTTGGTACAGGAGTACTTGTTGATGGCATGGACTTCTCAGACGATAA
AATGCTACAAGGTCGTACTTTCTCTTATTCAGATACGCAACGCTATCGCGTTGGTGCAAACTATCTGCAATTACCTGTTA
ATGCACCTAAAGCACCTGTTCGTACAAATCAACATCGTGGTCAAATGGATATGCGTAATCCGAAAGAGTCTGGAGAAAAT
CCGCATATTAACTATGAGCCATCTATGCTGGGTGGTTATAAAGATGCAAAACAAGAAAAGCACCATCCACACCAACCAAC
TTACAATGCGGCTGCTATGAGTGCACCAATCGATCGCCCTAATAATTATGGTCAAGCAGGTCACACATATCGTAGTTTTG
AGGAGTGGGAACGAAATGAGTTGGTTAAAAATCTATCTGAAGCACTTGCAGTATGTGACAAAAGAATTCAGAATGCGATG
ATTGAACACTTCACACAAGCTGATGAAGATTATGGCCGTCGTGTTAAAGAAGGTATTGAAAAGAAAATGAAAGAAGCTAA
AACGGAAAACAAACTTCCAGGTCGTGAAGTAAGTAAATCAAAATATGGACAAGGTTCATTAGCTGCAAACGAAGCAACAA
AAGATGCAGTGAAGAAAAGCCATGAATCAGATCCTTATTAA

Upstream 100 bases:

>100_bases
CTTGTTAATTGATACATTATAAATAATTTGCAATTCTATCATATTTTACCTAATAAATGGAAATACCTAAAGGTGAATAA
TTTTGAGGAGGTTTTCAATT

Downstream 100 bases:

>100_bases
TTAGACGTAAGCACAAAAGGATATACTTAGAGGTGCCGTTAAAACGGTTAGGTAGCCGTTCATACGATTGCTAAGTAGTT
TTGTTTAAAAATATGAGGGG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MEENQDMNSLDEQDVKRETLTTRQGHPVKDNQNIRTIGNRGPATLENYHFIEKISHFDREEVPERVVHARGAGAFGYFET
YGKVGDEPVEKYTRAKVFSGAGKKTPLMVRFSTVAGAKDSPETARDPRGFAVKMYTEDGNWDLVGNNLKIFFIRDAMKFP
DMIHAFKVDPVSNVANPQRMFDFVSRTPEATHMITFLFSPWGIPATYRHMQGSGVNTYKWVNEKGEAVLVKYHWEPKQGI
RNLTQEDANSIQAMNVSHATQDLYEAIERKDYPEWELFVQIMEDDYHPELDFDPLDDTKLWPEEQFPWLPVGRMVLDRNP
VDYHSDIEQAAFGTGVLVDGMDFSDDKMLQGRTFSYSDTQRYRVGANYLQLPVNAPKAPVRTNQHRGQMDMRNPKESGEN
PHINYEPSMLGGYKDAKQEKHHPHQPTYNAAAMSAPIDRPNNYGQAGHTYRSFEEWERNELVKNLSEALAVCDKRIQNAM
IEHFTQADEDYGRRVKEGIEKKMKEAKTENKLPGREVSKSKYGQGSLAANEATKDAVKKSHESDPY

Sequences:

>Translated_546_residues
MEENQDMNSLDEQDVKRETLTTRQGHPVKDNQNIRTIGNRGPATLENYHFIEKISHFDREEVPERVVHARGAGAFGYFET
YGKVGDEPVEKYTRAKVFSGAGKKTPLMVRFSTVAGAKDSPETARDPRGFAVKMYTEDGNWDLVGNNLKIFFIRDAMKFP
DMIHAFKVDPVSNVANPQRMFDFVSRTPEATHMITFLFSPWGIPATYRHMQGSGVNTYKWVNEKGEAVLVKYHWEPKQGI
RNLTQEDANSIQAMNVSHATQDLYEAIERKDYPEWELFVQIMEDDYHPELDFDPLDDTKLWPEEQFPWLPVGRMVLDRNP
VDYHSDIEQAAFGTGVLVDGMDFSDDKMLQGRTFSYSDTQRYRVGANYLQLPVNAPKAPVRTNQHRGQMDMRNPKESGEN
PHINYEPSMLGGYKDAKQEKHHPHQPTYNAAAMSAPIDRPNNYGQAGHTYRSFEEWERNELVKNLSEALAVCDKRIQNAM
IEHFTQADEDYGRRVKEGIEKKMKEAKTENKLPGREVSKSKYGQGSLAANEATKDAVKKSHESDPY
>Mature_546_residues
MEENQDMNSLDEQDVKRETLTTRQGHPVKDNQNIRTIGNRGPATLENYHFIEKISHFDREEVPERVVHARGAGAFGYFET
YGKVGDEPVEKYTRAKVFSGAGKKTPLMVRFSTVAGAKDSPETARDPRGFAVKMYTEDGNWDLVGNNLKIFFIRDAMKFP
DMIHAFKVDPVSNVANPQRMFDFVSRTPEATHMITFLFSPWGIPATYRHMQGSGVNTYKWVNEKGEAVLVKYHWEPKQGI
RNLTQEDANSIQAMNVSHATQDLYEAIERKDYPEWELFVQIMEDDYHPELDFDPLDDTKLWPEEQFPWLPVGRMVLDRNP
VDYHSDIEQAAFGTGVLVDGMDFSDDKMLQGRTFSYSDTQRYRVGANYLQLPVNAPKAPVRTNQHRGQMDMRNPKESGEN
PHINYEPSMLGGYKDAKQEKHHPHQPTYNAAAMSAPIDRPNNYGQAGHTYRSFEEWERNELVKNLSEALAVCDKRIQNAM
IEHFTQADEDYGRRVKEGIEKKMKEAKTENKLPGREVSKSKYGQGSLAANEATKDAVKKSHESDPY

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=488, Percent_Identity=43.6475409836066, Blast_Score=409, Evalue=1e-114,
Organism=Escherichia coli, GI48994891, Length=420, Percent_Identity=43.5714285714286, Blast_Score=334, Evalue=8e-93,
Organism=Caenorhabditis elegans, GI25147792, Length=498, Percent_Identity=42.3694779116466, Blast_Score=416, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI25151141, Length=504, Percent_Identity=42.0634920634921, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI71998444, Length=506, Percent_Identity=41.1067193675889, Blast_Score=411, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6320462, Length=523, Percent_Identity=36.7112810707457, Blast_Score=326, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6321525, Length=341, Percent_Identity=39.2961876832845, Blast_Score=253, Evalue=5e-68,
Organism=Drosophila melanogaster, GI17981717, Length=507, Percent_Identity=39.4477317554241, Blast_Score=397, Evalue=1e-110,
Organism=Drosophila melanogaster, GI19920968, Length=492, Percent_Identity=37.8048780487805, Blast_Score=378, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 62559; Mature: 62559

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENQDMNSLDEQDVKRETLTTRQGHPVKDNQNIRTIGNRGPATLENYHFIEKISHFDRE
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCHH
EVPERVVHARGAGAFGYFETYGKVGDEPVEKYTRAKVFSGAGKKTPLMVRFSTVAGAKDS
HHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC
PETARDPRGFAVKMYTEDGNWDLVGNNLKIFFIRDAMKFPDMIHAFKVDPVSNVANPQRM
CCCCCCCCCEEEEEEEECCCEEEECCCEEEEEEECCHHCHHHHHHEECCCHHHCCCHHHH
FDFVSRTPEATHMITFLFSPWGIPATYRHMQGSGVNTYKWVNEKGEAVLVKYHWEPKQGI
HHHHHCCCCHHEEEEEEECCCCCCHHHHHHCCCCCCHHHEECCCCCEEEEEEECCHHHHH
RNLTQEDANSIQAMNVSHATQDLYEAIERKDYPEWELFVQIMEDDYHPELDFDPLDDTKL
HHHHHHHHHHEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
WPEEQFPWLPVGRMVLDRNPVDYHSDIEQAAFGTGVLVDGMDFSDDKMLQGRTFSYSDTQ
CCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
RYRVGANYLQLPVNAPKAPVRTNQHRGQMDMRNPKESGENPHINYEPSMLGGYKDAKQEK
CEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHCCCHHHHHHC
HHPHQPTYNAAAMSAPIDRPNNYGQAGHTYRSFEEWERNELVKNLSEALAVCDKRIQNAM
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEHFTQADEDYGRRVKEGIEKKMKEAKTENKLPGREVSKSKYGQGSLAANEATKDAVKKS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHC
HESDPY
CCCCCC
>Mature Secondary Structure
MEENQDMNSLDEQDVKRETLTTRQGHPVKDNQNIRTIGNRGPATLENYHFIEKISHFDRE
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCHH
EVPERVVHARGAGAFGYFETYGKVGDEPVEKYTRAKVFSGAGKKTPLMVRFSTVAGAKDS
HHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC
PETARDPRGFAVKMYTEDGNWDLVGNNLKIFFIRDAMKFPDMIHAFKVDPVSNVANPQRM
CCCCCCCCCEEEEEEEECCCEEEECCCEEEEEEECCHHCHHHHHHEECCCHHHCCCHHHH
FDFVSRTPEATHMITFLFSPWGIPATYRHMQGSGVNTYKWVNEKGEAVLVKYHWEPKQGI
HHHHHCCCCHHEEEEEEECCCCCCHHHHHHCCCCCCHHHEECCCCCEEEEEEECCHHHHH
RNLTQEDANSIQAMNVSHATQDLYEAIERKDYPEWELFVQIMEDDYHPELDFDPLDDTKL
HHHHHHHHHHEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
WPEEQFPWLPVGRMVLDRNPVDYHSDIEQAAFGTGVLVDGMDFSDDKMLQGRTFSYSDTQ
CCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
RYRVGANYLQLPVNAPKAPVRTNQHRGQMDMRNPKESGENPHINYEPSMLGGYKDAKQEK
CEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHCCCHHHHHHC
HHPHQPTYNAAAMSAPIDRPNNYGQAGHTYRSFEEWERNELVKNLSEALAVCDKRIQNAM
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEHFTQADEDYGRRVKEGIEKKMKEAKTENKLPGREVSKSKYGQGSLAANEATKDAVKKS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHC
HESDPY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]