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The map label for this gene is fabH [H]

Identifier: 52142302

GI number: 52142302

Start: 3073279

End: 3074268

Strand: Reverse

Name: fabH [H]

Synonym: BCZK2940

Alternate gene names: 52142302

Gene position: 3074268-3073279 (Counterclockwise)

Preceding gene: 52142301

Following gene: 52142304

Centisome position: 58.0

GC content: 37.27

Gene sequence:

>990_bases
ATGAAAAGATATATTAGTATAAAAGGAATTGGAACATATCTTCCAAAACGAAAAGTAGATTCTCTTGAAATAGATCGTAT
GCTAGACGTACCAGAAGGCTGGACATTAAAAAAAGCTGGGGTAAAAACACGATACTTTGTTGATGGGGAAACGTCTTCTT
ATATGGGGGCTGAGGCTGCAAAAAAAGCTGTAGAAGATGCGAAGTTAACATGGGATGATATCGATTGTATTATTTGCGGA
AGCGGAACGATTCAACAGGCGATTCCTTCTACTGCATCACTTATTCAAGAACAGCTCGGGCTACAGCATTCTGGTATTCC
ATGTTTTGATATCAATTCAACATGTTTAAGTTTCATAACAGCACTTGATACAATTTCATACACAATTGAATGCGGGAGAT
ACAAAAATGTTGTTATTATTTCTTCTGAAATTTCTTCTGTTGGATTAAATTGGGGACAAAATGAAAGCAGTATTTTATTC
GGTGACGGTGCGGCAGCTGTTGTCATAACAAAAGGCGATCATTCATCTTCTATTATTGCTTCCCATATGGAAACATATAG
CTCTGGTGCGCATTTATCAGAAATTCGTGGCGGTGGAACGATGATTCATCCTAGGGAATATAGTGAGGAACGAAAAGAAG
ACTTCTTGTTCGATATGAATGGAAGAGCCATTTTTAAACTATCTTCTAAGTATTTAATGAAGTTTATCGACAAGCTCCTT
ATGGATACTGGTTATTCTCTAGCCGATATTGATTTAATTGTTCCTCACCAAGCAAGTGGACCAGCTATGAGACTCATTCG
TAAAAAATTAGGGGTAGATGAAGAACGCTTTATGACTATTTTTGAAGACTACGGCAATATGATTTCCGCATCTATTCCAG
TCGCTCTTTTCGAAGCGATTAAGCAAAAGAAAGTGCAACGTGGAAATAAAATATTATTATTAGGTACTTCTGCGGGACTT
TCTATCGGGGGCATCCTTCTTGAATACTAA

Upstream 100 bases:

>100_bases
GGGATAGCAGAATTCCACAAAAAAATCTGTATGTATCCACAACAGTAGTTATATATGACGGAATTTTTGAATTTATAAAA
AGATTAAGAGGCGATAGAAA

Downstream 100 bases:

>100_bases
GAAAACAGTATTAATTACAGGGGCACGTGCACCAGCAACTTTGCATTTATGCAGACTGTTTCATAACGCTGGACATACCG
TTATTATTGCAGATAGTATT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKRYISIKGIGTYLPKRKVDSLEIDRMLDVPEGWTLKKAGVKTRYFVDGETSSYMGAEAAKKAVEDAKLTWDDIDCIICG
SGTIQQAIPSTASLIQEQLGLQHSGIPCFDINSTCLSFITALDTISYTIECGRYKNVVIISSEISSVGLNWGQNESSILF
GDGAAAVVITKGDHSSSIIASHMETYSSGAHLSEIRGGGTMIHPREYSEERKEDFLFDMNGRAIFKLSSKYLMKFIDKLL
MDTGYSLADIDLIVPHQASGPAMRLIRKKLGVDEERFMTIFEDYGNMISASIPVALFEAIKQKKVQRGNKILLLGTSAGL
SIGGILLEY

Sequences:

>Translated_329_residues
MKRYISIKGIGTYLPKRKVDSLEIDRMLDVPEGWTLKKAGVKTRYFVDGETSSYMGAEAAKKAVEDAKLTWDDIDCIICG
SGTIQQAIPSTASLIQEQLGLQHSGIPCFDINSTCLSFITALDTISYTIECGRYKNVVIISSEISSVGLNWGQNESSILF
GDGAAAVVITKGDHSSSIIASHMETYSSGAHLSEIRGGGTMIHPREYSEERKEDFLFDMNGRAIFKLSSKYLMKFIDKLL
MDTGYSLADIDLIVPHQASGPAMRLIRKKLGVDEERFMTIFEDYGNMISASIPVALFEAIKQKKVQRGNKILLLGTSAGL
SIGGILLEY
>Mature_329_residues
MKRYISIKGIGTYLPKRKVDSLEIDRMLDVPEGWTLKKAGVKTRYFVDGETSSYMGAEAAKKAVEDAKLTWDDIDCIICG
SGTIQQAIPSTASLIQEQLGLQHSGIPCFDINSTCLSFITALDTISYTIECGRYKNVVIISSEISSVGLNWGQNESSILF
GDGAAAVVITKGDHSSSIIASHMETYSSGAHLSEIRGGGTMIHPREYSEERKEDFLFDMNGRAIFKLSSKYLMKFIDKLL
MDTGYSLADIDLIVPHQASGPAMRLIRKKLGVDEERFMTIFEDYGNMISASIPVALFEAIKQKKVQRGNKILLLGTSAGL
SIGGILLEY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=27.82874617737, Blast_Score=154, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36138; Mature: 36138

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYISIKGIGTYLPKRKVDSLEIDRMLDVPEGWTLKKAGVKTRYFVDGETSSYMGAEAA
CCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCHHHH
KKAVEDAKLTWDDIDCIICGSGTIQQAIPSTASLIQEQLGLQHSGIPCFDINSTCLSFIT
HHHHHHCCCEECCCCEEEECCCHHHHHCCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHH
ALDTISYTIECGRYKNVVIISSEISSVGLNWGQNESSILFGDGAAAVVITKGDHSSSIIA
HHHHHEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHH
SHMETYSSGAHLSEIRGGGTMIHPREYSEERKEDFLFDMNGRAIFKLSSKYLMKFIDKLL
HHHHHHCCCCCHHHHCCCCCEECCHHHHHHHHHCCEEECCCCEEEEECHHHHHHHHHHHH
MDTGYSLADIDLIVPHQASGPAMRLIRKKLGVDEERFMTIFEDYGNMISASIPVALFEAI
HHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCHHHHHHHH
KQKKVQRGNKILLLGTSAGLSIGGILLEY
HHHHHHCCCEEEEEECCCCCEECCEEECC
>Mature Secondary Structure
MKRYISIKGIGTYLPKRKVDSLEIDRMLDVPEGWTLKKAGVKTRYFVDGETSSYMGAEAA
CCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCHHHH
KKAVEDAKLTWDDIDCIICGSGTIQQAIPSTASLIQEQLGLQHSGIPCFDINSTCLSFIT
HHHHHHCCCEECCCCEEEECCCHHHHHCCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHH
ALDTISYTIECGRYKNVVIISSEISSVGLNWGQNESSILFGDGAAAVVITKGDHSSSIIA
HHHHHEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHH
SHMETYSSGAHLSEIRGGGTMIHPREYSEERKEDFLFDMNGRAIFKLSSKYLMKFIDKLL
HHHHHHCCCCCHHHHCCCCCEECCHHHHHHHHHCCEEECCCCEEEEECHHHHHHHHHHHH
MDTGYSLADIDLIVPHQASGPAMRLIRKKLGVDEERFMTIFEDYGNMISASIPVALFEAI
HHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCHHHHHHHH
KQKKVQRGNKILLLGTSAGLSIGGILLEY
HHHHHHCCCEEEEEECCCCCEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]