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The map label for this gene is lutA1 [H]

Identifier: 52142284

GI number: 52142284

Start: 3091325

End: 3092053

Strand: Reverse

Name: lutA1 [H]

Synonym: BCZK2958

Alternate gene names: 52142284

Gene position: 3092053-3091325 (Counterclockwise)

Preceding gene: 52142281

Following gene: 52142285

Centisome position: 58.33

GC content: 37.72

Gene sequence:

>729_bases
ATGAAAGTCTCGTTATTTATTACTTGTTTATCAGATGTGTTTTTTCCTCAAGTAGGTAGGAGTGTCGTAGAAATTATGAA
TCAATGTGGAGTGGAACTAGATTTCCCTGAAGGACAGACTTGTTGCGGACAACCAGCTTACAATAGTGGATATCAAGAAG
ATGCAAAACTAGCAGCAAAGCAAATGATTAAAGCATTTGAACATAGTGAATATATTGTGACCCCTTCAGGTTCTTGCGCT
AGCATGGTTCATCATTATTATAAAGAGATGTTTAAAGGTGATAGTGAATGGTATGAAAAAGCGGTTCATTTAGCGGATAG
AACGTATGAGTTGACGGACTTTTTAGTGAATGTACTTGGGAAAAATGATTGGAAATCTAAGTTGGTTGAGAAAGCTGTTT
TCCATCAATCTTGTCATATGAGTCGGGCGCTCGGGATCAAAGAGGAACCACTGAAGTTATTATCGCAAGTAGAAGGTCTA
GACATAAAAGAATTACCATATTGCCAAGATTGCTGCGGGTTTGGTGGTACTTTTGCAGTGAAAATGAGCTCGATTTCTGA
AACGATGGTTGATGAAAAAATAAAACATATTGAGGCGACAGAAGCAAATCTCTTAATTGGAGCAGATATGGGATGTCTTA
TGAATATTGGGGGAAGATTGCGCAGGAAAAATAAAAATATTCAAGTGTTACATGTAGCAGAAGTACTGGCGAAGGGGCTG
AATAAATGA

Upstream 100 bases:

>100_bases
AACAAAAAGTTTTAAAAATAGAAAATTCTAAAAATTTAAAATAATTTTCAGAAAAGTAATAACTTGAAAATAGATCATAT
CGTTTTGAGGGGGGATTTTG

Downstream 100 bases:

>100_bases
GTGTGGCGGGGGAACTAGATTTTTTGAAAAGAGTAGATAAAGCGTTGCATGATCCGCAGATGAGAAGCGCGGTTCCGTTT
ACACAAGATCGGCTTCGGAT

Product: (S)-2-hydroxy-acid oxidase, iron-sulfur subunit

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKVSLFITCLSDVFFPQVGRSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCA
SMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLGKNDWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGL
DIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
NK

Sequences:

>Translated_242_residues
MKVSLFITCLSDVFFPQVGRSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCA
SMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLGKNDWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGL
DIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
NK
>Mature_242_residues
MKVSLFITCLSDVFFPQVGRSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCA
SMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLGKNDWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGL
DIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
NK

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=237, Percent_Identity=43.4599156118143, Blast_Score=213, Evalue=8e-57,
Organism=Escherichia coli, GI48994913, Length=250, Percent_Identity=22, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788576, Length=214, Percent_Identity=24.2990654205607, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: 1.1.3.15

Molecular weight: Translated: 27074; Mature: 27074

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSLFITCLSDVFFPQVGRSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
QMIKAFEHSEYIVTPSGSCASMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLG
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KNDWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGLDIKELPYCQDCCGFGGTFAV
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEE
KMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
EHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
NK
CC
>Mature Secondary Structure
MKVSLFITCLSDVFFPQVGRSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
QMIKAFEHSEYIVTPSGSCASMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLG
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KNDWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGLDIKELPYCQDCCGFGGTFAV
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEE
KMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
EHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
NK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA