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The map label for this gene is tkt [H]

Identifier: 52142162

GI number: 52142162

Start: 3210472

End: 3212466

Strand: Reverse

Name: tkt [H]

Synonym: BCZK3082

Alternate gene names: 52142162

Gene position: 3212466-3210472 (Counterclockwise)

Preceding gene: 52142159

Following gene: 52142161

Centisome position: 60.6

GC content: 39.65

Gene sequence:

>1995_bases
ATGATACAAAACATAAATCAATTAGCAGTGAATACAATTCGTACGTTATCAATTGATGCTATTAATGCGGCAAATTCAGG
TCATCCAGGTCTTCCGATGGGAGCAGCGCCAATGGCTTATGCATTATGGGCGAATCATTTAAATCATAATCCTAATCATC
CAAAATGGTTTAACCGTGATCGCTTCGTTTTATCGGCGGGACATGGATCTAGCTTATTATATAGCCTACTTCATTTAGCT
GGATATGACGTTTCAATTGATGACTTGAAAAACTTCAGAAAGTTAAATAGTAAAACACCAGGACATCCTGAGTTTGGTCA
TACTTCTGGAGTTGAAGCGACAACGGGCCCGTTAGGACAAGGGATTGCCAATGCTGTCGGAATGGCAATGGCAGAAGCGC
ATTTAGCAGCGAAATTTAATAAGGATGGTCACTCTATTATTGATCACAATACGTACGCTTTAGTTGGAGACGGTGATTTA
ATGGAAGGTGTCGCTTATGAAGCGATGTCAATGGCAGGACATATGAAACTTGGCAAGTTAATTGTGCTGTATGATTCAAA
TGAAATTTCACTTGATGGTGAATTAAACATTGCTTTCTCTGAAGATATGCAGAAAAGGGTAGAATCTGCACATTGGCAAT
ATATAAGAGTTGAAGATGGAAACGATGTTGATGCGATTACAAAAGCGATTCAATTAGCGAAAGATAATGCGGACCAACCT
ACTCTTATAGAAATTAGAACCATTATAGGTTACGGAAGTCCAAAAGTTGCTGGAACGAACAAAGCACACGGTAACCCGCT
TGGATTAGAAGAAGCGACAGCGACAAAACAAGTGTATGGTTGGCATTATGAAGAAGACTTCTTTGTACCTGAAGAAGTAA
CAGCTCATTTTAATGAACTGAAACAAAAAGGTATTGAAAAAGAAAATGGCTGGAATGAGCAGTTCAACTTATACAGAGAG
TCAAATCCTGCACTAGCAGATGAATTAGAAAAAGCAATTACAGGTGAAGTTTTAATCGAAGCGAAAGACATTCTATCCTT
CGATACTGAAAAAACGATTTCAACTCGTGTTGCAAGTGGGGAAGCTATTAACCATTATGTGAAATCGATTCCTTCTATTT
TCGGTGGAAGTGCGGATCTTTCTCATTCTACGATGACAGATATAAAAGGTGAAGCAGTGTATGCGGTAGAATCGTATGCT
GGCCGAAATATATACTTTGGTGTACGTGAACATGCAATGGGCGCAGCAGCGAATGGACTGGCTCTTCATGGAGGAGTAAA
ACCGTTCGTGAGTACATTCTTTGTATTTAATGACTATCTTCGTCCATCTATTCGACTGGCTGCATTGCAAAAGTTACCTG
TTACGTATGTATTTACACATGATTCGATTGCTGTAGGAGAAGATGGTCCAACGCATGAACCTATTGAACATTTAGCAGCT
CTTCGGGCAATTCCTGGTTTAACAGTTATCCGTCCGTCAGATGCAAATGAAACAGCAAGTGCGTGGGCGTATGCTTTACA
GCAAACCGATGGTCCAGTCGTTTTAGTACTTAGCCGTCAAAATTTACCGGTGTTTAATGAAACGAAAGCAAACATAGAGA
ATCTTTCTAAAGGAGCTTACGTATTAACACAAACGAATGAAAATCCGGATGTAATTTTAATTGCGACAGGTTCTGAAGTA
TCCTTAGCTGCTAGTGCGAAAGCGAAACTAGAAGAAGACAATGTCTCTGTTCGTATCGTTGCAATGCCGAGCTGGGAATT
ATTCGATCACCAATCGAAAGAATATAAGGAATCCGTTCTTCCGTCTTCTGTAACGAAACGAGTATCTCTTGAGATGGGCG
TATCTCTCGGCTGGGAGCGTTATGTAGGACAAGAAGGAAACATATTATCGATTGAAACATTTGGAGCTTCAGGAACTGGG
GCTGAAGTCATGAATCTATTTGGATTTACGACAGAAAACGTTGTTCAAATTACTAAAAATGTATTGAATTCTTAA

Upstream 100 bases:

>100_bases
TAATGAATTATTGCAAGAAAGTGGATTTAAATGGTGGTTAGATCAAGAAACGAAAAAATAAGTACTTTCTTTCATGAAAG
CATGTAGGGGGACGATTACT

Downstream 100 bases:

>100_bases
GCTATGACTGTGAATACCTTTCCGTACATATCAGTGCTGCAAGGTATTCCAGATTGTAGTGATATGAATTTTTAATAAAA
GAGGATTTGAGGAGGAATTA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MIQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDL
MEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYIRVEDGNDVDAITKAIQLAKDNADQP
TLIEIRTIIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKENGWNEQFNLYRE
SNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYA
GRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTQTNENPDVILIATGSEV
SLAASAKAKLEEDNVSVRIVAMPSWELFDHQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSIETFGASGTG
AEVMNLFGFTTENVVQITKNVLNS

Sequences:

>Translated_664_residues
MIQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDL
MEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYIRVEDGNDVDAITKAIQLAKDNADQP
TLIEIRTIIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKENGWNEQFNLYRE
SNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYA
GRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTQTNENPDVILIATGSEV
SLAASAKAKLEEDNVSVRIVAMPSWELFDHQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSIETFGASGTG
AEVMNLFGFTTENVVQITKNVLNS
>Mature_664_residues
MIQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDL
MEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYIRVEDGNDVDAITKAIQLAKDNADQP
TLIEIRTIIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKENGWNEQFNLYRE
SNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYA
GRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTQTNENPDVILIATGSEV
SLAASAKAKLEEDNVSVRIVAMPSWELFDHQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSIETFGASGTG
AEVMNLFGFTTENVVQITKNVLNS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=671, Percent_Identity=26.6766020864382, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI4507521, Length=671, Percent_Identity=26.6766020864382, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI133778974, Length=662, Percent_Identity=25.6797583081571, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI225637459, Length=680, Percent_Identity=21.4705882352941, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI225637463, Length=596, Percent_Identity=21.8120805369128, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI225637461, Length=596, Percent_Identity=21.8120805369128, Blast_Score=122, Evalue=8e-28,
Organism=Escherichia coli, GI48994911, Length=658, Percent_Identity=48.3282674772036, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=47.4474474474475, Blast_Score=625, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17539652, Length=667, Percent_Identity=25.3373313343328, Blast_Score=168, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6325331, Length=669, Percent_Identity=46.3378176382661, Blast_Score=584, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6319593, Length=674, Percent_Identity=44.0652818991098, Blast_Score=552, Evalue=1e-158,
Organism=Drosophila melanogaster, GI45551847, Length=673, Percent_Identity=27.7860326894502, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI45550715, Length=673, Percent_Identity=27.7860326894502, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24645119, Length=633, Percent_Identity=27.4881516587678, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24666278, Length=678, Percent_Identity=26.2536873156342, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72162; Mature: 72162

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRD
CCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
RFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQ
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDLMEGVAYEAMSMAGHMKLGKL
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEECCE
IVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYIRVEDGNDVDAITKAIQLAKDNADQP
EEEECCCEEEECCEEEEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCCCC
TLIEIRTIIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNEL
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCCCHHHHHHHHHHH
KQKGIEKENGWNEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASG
HHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHCCC
EAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREHAMGAAANGL
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHHHCCCCCCCE
ALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHH
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAY
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
VLTQTNENPDVILIATGSEVSLAASAKAKLEEDNVSVRIVAMPSWELFDHQSKEYKESVL
EEEECCCCCCEEEEECCCCEEEEECCHHEECCCCEEEEEEEECCHHHHCCCHHHHHHHCC
PSSVTKRVSLEMGVSLGWERYVGQEGNILSIETFGASGTGAEVMNLFGFTTENVVQITKN
CHHHHHHEEEECCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHH
VLNS
HHCC
>Mature Secondary Structure
MIQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRD
CCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
RFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQ
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDLMEGVAYEAMSMAGHMKLGKL
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEECCE
IVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYIRVEDGNDVDAITKAIQLAKDNADQP
EEEECCCEEEECCEEEEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCCCC
TLIEIRTIIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNEL
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCCCHHHHHHHHHHH
KQKGIEKENGWNEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASG
HHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHCCC
EAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREHAMGAAANGL
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHHHCCCCCCCE
ALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHH
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAY
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
VLTQTNENPDVILIATGSEVSLAASAKAKLEEDNVSVRIVAMPSWELFDHQSKEYKESVL
EEEECCCCCCEEEEECCCCEEEEECCHHEECCCCEEEEEEEECCHHHHCCCHHHHHHHCC
PSSVTKRVSLEMGVSLGWERYVGQEGNILSIETFGASGTGAEVMNLFGFTTENVVQITKN
CHHHHHHEEEECCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHH
VLNS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]