Click here to switch to the map view.

The map label for this gene is yrkL [H]

Identifier: 52142114

GI number: 52142114

Start: 3258002

End: 3258538

Strand: Reverse

Name: yrkL [H]

Synonym: BCZK3128

Alternate gene names: 52142114

Gene position: 3258538-3258002 (Counterclockwise)

Preceding gene: 52142110

Following gene: 52142116

Centisome position: 61.47

GC content: 32.59

Gene sequence:

>537_bases
ATGATGAGAACACTTGTAATTGTAGCACACCCTCATATTGAAAAATCAAAAATTAATAAAAGATGGACAGAAGAACTTGA
GAAACATTCAGATGAAATTACGGTGCATGAATTATATAAAGTGGCACCAAACTGGGAGTTTAATATTGAAGAAGAGCAAA
AGTTATTAGTAGAACATGACAGATATATATTTCAATTCCCGCTATACTGGTACAGCACACCGCCATTATTAAAAAAATGG
TTTGATGATGTATTAACATATGGATTTGCATACGGATCAAAAGGGGATAAAGTGAAGGGAAAAGAGTTTGGTGTAGCAGT
TTCTATAGGTGGATTAGAAAAAGATTATGAAAATAGCGGAATTACGATGGATGAGTTGACGAAACCATTCCAAGCTACAT
GCCTATATACAGGTATGGAATTTATACCTTCATTTTATTTATATGGTGCCGAATATAAACTAAGTGATGAAGAGATTGAT
AAAAGTGCACCTGAGTATGTGCGATATGTAATGAATAAGAAGTATTCTAATATATAA

Upstream 100 bases:

>100_bases
CAAGGTTCCTATAGCACCTGAAAGTACGTACTTTTCAATTATATGTAATGCATTCATACTAATATGTAAAGGATTGATTC
ATTTATAAAGGGGATGGAAA

Downstream 100 bases:

>100_bases
GAAGAAACAGCCATTTACTTGTGAAGTAAATGGCTATTTTATATTCTTATTATATTCACTAAGTGTAATCTTTAGTAAAT
TAATAGTTAATCTGGTAAAA

Product: NAD(P)H oxidoreductase

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MMRTLVIVAHPHIEKSKINKRWTEELEKHSDEITVHELYKVAPNWEFNIEEEQKLLVEHDRYIFQFPLYWYSTPPLLKKW
FDDVLTYGFAYGSKGDKVKGKEFGVAVSIGGLEKDYENSGITMDELTKPFQATCLYTGMEFIPSFYLYGAEYKLSDEEID
KSAPEYVRYVMNKKYSNI

Sequences:

>Translated_178_residues
MMRTLVIVAHPHIEKSKINKRWTEELEKHSDEITVHELYKVAPNWEFNIEEEQKLLVEHDRYIFQFPLYWYSTPPLLKKW
FDDVLTYGFAYGSKGDKVKGKEFGVAVSIGGLEKDYENSGITMDELTKPFQATCLYTGMEFIPSFYLYGAEYKLSDEEID
KSAPEYVRYVMNKKYSNI
>Mature_178_residues
MMRTLVIVAHPHIEKSKINKRWTEELEKHSDEITVHELYKVAPNWEFNIEEEQKLLVEHDRYIFQFPLYWYSTPPLLKKW
FDDVLTYGFAYGSKGDKVKGKEFGVAVSIGGLEKDYENSGITMDELTKPFQATCLYTGMEFIPSFYLYGAEYKLSDEEID
KSAPEYVRYVMNKKYSNI

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=96, Percent_Identity=39.5833333333333, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786231, Length=168, Percent_Identity=34.5238095238095, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1789750, Length=173, Percent_Identity=32.3699421965318, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 20981; Mature: 20981

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRTLVIVAHPHIEKSKINKRWTEELEKHSDEITVHELYKVAPNWEFNIEEEQKLLVEHD
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCC
RYIFQFPLYWYSTPPLLKKWFDDVLTYGFAYGSKGDKVKGKEFGVAVSIGGLEKDYENSG
CEEEEECHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
ITMDELTKPFQATCLYTGMEFIPSFYLYGAEYKLSDEEIDKSAPEYVRYVMNKKYSNI
CCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMRTLVIVAHPHIEKSKINKRWTEELEKHSDEITVHELYKVAPNWEFNIEEEQKLLVEHD
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCC
RYIFQFPLYWYSTPPLLKKWFDDVLTYGFAYGSKGDKVKGKEFGVAVSIGGLEKDYENSG
CEEEEECHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
ITMDELTKPFQATCLYTGMEFIPSFYLYGAEYKLSDEEIDKSAPEYVRYVMNKKYSNI
CCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]