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The map label for this gene is fdhC [H]

Identifier: 52141763

GI number: 52141763

Start: 3611013

End: 3611828

Strand: Direct

Name: fdhC [H]

Synonym: BCZK3485

Alternate gene names: 52141763

Gene position: 3611013-3611828 (Clockwise)

Preceding gene: 52141764

Following gene: 52141761

Centisome position: 68.12

GC content: 36.64

Gene sequence:

>816_bases
ATGTCTGTATTTACACCAGAAGAAATTACGGAACTTGCTGCTAATTCTGGAAGAAAAAAAGCTCATTTATCACTACTCCC
TATGCTAATTCTCGGTTTTTTTGGCGGTGCTTTCATAGCATTAGGGTATTTACTCGATATTCATGTTATTGGAACAATGC
CAAAGGCTTGGGGATCATTTACTAGTTTTCTAGGTGCCGCTGTATTCCCTATCGGTCTTATACTCGTTATTCTTGCAGGC
GGTGAGTTAGTAACTGGTAATATGATGACCGTTTCAATGGCGTGGCTTCATAAAAAAATCGACTTATTTCACTTCATTCG
AAATTTAGTTATTGTTACGTTTAGCAACTTCATAGGTGCTGTATTCGTTGCTTATTTTTTCGGTCATATCGTCGGATTAA
CAGAGGGAGCTTTTTTAGCGAAAACAGTTTCTGTTGCGCAAGCTAAACTACAAGATACACCACTACAAGCTTTCATTTCT
GCAATCGGATGTAATTGGCTCGTTTGTTTAGCTGTTTGGCTCAGTATGGGAAGTAAAGAATTTATCGGAAAGATTATCGG
TATTTGGTTCCCAGTTATGACTTTTGTTGCAATTGGATTTCAACACGTTGTAGCCAATATGTTTGTCATCCCAGCTGCTA
TTTTTGCCGGTCATTTAACTTGGATTGAATATTTTCCAAACTTTATTTTTGTTTTCTTCGGAAACTTAGTAGGCGGTATG
TTATTTGTGGCATTACCTTATTTTATATCTTATAAAAAGAAACTGCCTTCCAAAGAAGAACAAACCGCATTAAAGAAAAA
ATCTGTATCCGCTTAA

Upstream 100 bases:

>100_bases
GACAAATTTATACAGAAGTCATAACATATTTTTATAATACATAGATTCTTAAAAATGTTCCATCTATTTATTTTATCATT
GTATTAAGGAGAGATTATCC

Downstream 100 bases:

>100_bases
ATGGAACGACTATACAGCAATCCTGAAAAATATTACAAATTCTATTTTTTTTTTTGCGAATATATGTACGTACACTTGTT
CTCGAATGTTTTATACGTTA

Product: formate transporter

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSVFTPEEITELAANSGRKKAHLSLLPMLILGFFGGAFIALGYLLDIHVIGTMPKAWGSFTSFLGAAVFPIGLILVILAG
GELVTGNMMTVSMAWLHKKIDLFHFIRNLVIVTFSNFIGAVFVAYFFGHIVGLTEGAFLAKTVSVAQAKLQDTPLQAFIS
AIGCNWLVCLAVWLSMGSKEFIGKIIGIWFPVMTFVAIGFQHVVANMFVIPAAIFAGHLTWIEYFPNFIFVFFGNLVGGM
LFVALPYFISYKKKLPSKEEQTALKKKSVSA

Sequences:

>Translated_271_residues
MSVFTPEEITELAANSGRKKAHLSLLPMLILGFFGGAFIALGYLLDIHVIGTMPKAWGSFTSFLGAAVFPIGLILVILAG
GELVTGNMMTVSMAWLHKKIDLFHFIRNLVIVTFSNFIGAVFVAYFFGHIVGLTEGAFLAKTVSVAQAKLQDTPLQAFIS
AIGCNWLVCLAVWLSMGSKEFIGKIIGIWFPVMTFVAIGFQHVVANMFVIPAAIFAGHLTWIEYFPNFIFVFFGNLVGGM
LFVALPYFISYKKKLPSKEEQTALKKKSVSA
>Mature_270_residues
SVFTPEEITELAANSGRKKAHLSLLPMLILGFFGGAFIALGYLLDIHVIGTMPKAWGSFTSFLGAAVFPIGLILVILAGG
ELVTGNMMTVSMAWLHKKIDLFHFIRNLVIVTFSNFIGAVFVAYFFGHIVGLTEGAFLAKTVSVAQAKLQDTPLQAFISA
IGCNWLVCLAVWLSMGSKEFIGKIIGIWFPVMTFVAIGFQHVVANMFVIPAAIFAGHLTWIEYFPNFIFVFFGNLVGGML
FVALPYFISYKKKLPSKEEQTALKKKSVSA

Specific function: Involved In The Bidirectional Transport Of Formate (By Similarity). [C]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1788837, Length=271, Percent_Identity=30.2583025830258, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787132, Length=275, Percent_Identity=29.8181818181818, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87082249, Length=267, Percent_Identity=30.7116104868914, Blast_Score=90, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321779, Length=287, Percent_Identity=27.1777003484321, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: 1.2.1.2

Molecular weight: Translated: 29662; Mature: 29531

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVFTPEEITELAANSGRKKAHLSLLPMLILGFFGGAFIALGYLLDIHVIGTMPKAWGSF
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TSFLGAAVFPIGLILVILAGGELVTGNMMTVSMAWLHKKIDLFHFIRNLVIVTFSNFIGA
HHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVAYFFGHIVGLTEGAFLAKTVSVAQAKLQDTPLQAFISAIGCNWLVCLAVWLSMGSKE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
FIGKIIGIWFPVMTFVAIGFQHVVANMFVIPAAIFAGHLTWIEYFPNFIFVFFGNLVGGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVALPYFISYKKKLPSKEEQTALKKKSVSA
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]