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The map label for this gene is cad [H]

Identifier: 52141527

GI number: 52141527

Start: 3859173

End: 3860654

Strand: Direct

Name: cad [H]

Synonym: BCZK3722

Alternate gene names: 52141527

Gene position: 3859173-3860654 (Clockwise)

Preceding gene: 52141529

Following gene: 52141522

Centisome position: 72.8

GC content: 38.19

Gene sequence:

>1482_bases
GTGTATAGATTGTCCCAATACGAAACACCATTGTTTACCGCTTTAGTTGAGCACAGTAAGCGAAATCCAATTCAATTCCA
TATTCCAGGTCATAAAAAAGGGCAAGGCATGGATCCTGAATTTCGCGAATTTATTGGGCATAATGCATTAGCAATTGATT
TAATTAACATTGCGCCGCTCGATGATTTACATCATCCAAAAGGTATGATTAAAGAAGCACAAGATTTAGCAGCCGCTGCA
TTTGGTGCGGATCATACTTTCTTTTCTATTCAAGGTACAAGTGGCGCAATAATGACAATGGTAATGAGCGTTTGCGGTCC
TGGTGACAAAATACTAGTGCCACGAAACGTGCATAAATCAGTAATGTCAGCTATTATTTTCTCAGGTGCAAAACCTATTT
TCATGCATCCTGAAATCGACCCAAAACTTGGTATTTCACATGGAATCACAATCCAATCTGTCAAAAAAGCACTTGAAGAG
CACTCAGATGCGAAAGGCTTACTTGTTATTAATCCAACATACTTTGGCTTTGCTGCGGACTTAGAGCAGATTGTACAATT
AGCACATTCTTACGATATCCCTGTACTCGTTGATGAGGCTCATGGTGTTCATATTCATTTTCACGATGAACTGCCGATGT
CAGCGATGCAAGCCGGTGCAGATATGGCAGCAACGAGTGTTCACAAATTAGGTGGATCTTTAACGCAAAGTTCTATTCTT
AATGTAAAAGAAGGCCTTGTGAACGTAAAACATGTTCAATCTATTATTAGCATGCTTACGACTACATCAACGTCTTATAT
CTTGTTAGCCTCCCTAGATGTTGCTAGAAAACGTCTTGCTACAGAAGGAAAGGCACTCATAGAACAAACAATACAATTAG
CTGAACAAGTTCGTAATGCTATAAATGATATTGAACATCTTTACTGTCCAGGGAAAGAAACGCTAGGTACGGATGCTACT
TTTAACTATGATCCTACAAAGATAATTGTATCTGTAAAAGATTTAGGTATTACAGGCCATCAGGCTGAAGTATGGCTTAG
AGAGCAATATAACATTGAAGTAGAACTCTCAGATTTATACAACATACTATGTCTTGTCACTTTTGGGGATACAGAAAGTG
AGACGAATACACTTATTGCGGCATTACAAGATTTATCAGCAACATTTAAAAATAAAGCTGATAAAGGTGTTCAAGTGCAA
GTAGAAATTCCAGAAATACCTGTGTTAGCACTTTCTCCTCGAGATGCTTTTTATTCGGAAACAGAAGTCATCTCATTTGA
AAATGCAGCAGGTCGTATTATAGCTGATTTCGTTATGGTTTATCCGCCAGGGATTCCAATCTTTACTCCGGGGGAAATTA
TTACACAAGACAACTTAGAGTATATTCGTAAAAACTTAGAAGCAGGTTTACCTGTACAAGGTCCTGAAGATATGACATTA
CAAACATTACGCGTGATCAAAGAGTACAAGCCTATCAGTTGA

Upstream 100 bases:

>100_bases
GTGAATGGCAGAAAAACAAGTCTCATTCTAAAAAAGAACTTAACTTTTTTAGAATGAGATTATATAAAACAAACTCTAAT
AAATATTAAAAAAAGAAGGG

Downstream 100 bases:

>100_bases
TAGGCTTTTCTTTCACCCTTTTTCCCTTTTCTCATACGATATTATGTAATGTAACGTATAGGTGGGGATACTACTATGAT
TGTAATAGGCCGTTCTATTG

Product: lysine decarboxylase; arginine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MYRLSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDLHHPKGMIKEAQDLAAAA
FGADHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEE
HSDAKGLLVINPTYFGFAADLEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSIL
NVKEGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAINDIEHLYCPGKETLGTDAT
FNYDPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNILCLVTFGDTESETNTLIAALQDLSATFKNKADKGVQVQ
VEIPEIPVLALSPRDAFYSETEVISFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTL
QTLRVIKEYKPIS

Sequences:

>Translated_493_residues
MYRLSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDLHHPKGMIKEAQDLAAAA
FGADHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEE
HSDAKGLLVINPTYFGFAADLEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSIL
NVKEGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAINDIEHLYCPGKETLGTDAT
FNYDPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNILCLVTFGDTESETNTLIAALQDLSATFKNKADKGVQVQ
VEIPEIPVLALSPRDAFYSETEVISFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTL
QTLRVIKEYKPIS
>Mature_493_residues
MYRLSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDLHHPKGMIKEAQDLAAAA
FGADHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEE
HSDAKGLLVINPTYFGFAADLEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSIL
NVKEGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAINDIEHLYCPGKETLGTDAT
FNYDPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNILCLVTFGDTESETNTLIAALQDLSATFKNKADKGVQVQ
VEIPEIPVLALSPRDAFYSETEVISFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTL
QTLRVIKEYKPIS

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=563, Percent_Identity=24.1563055062167, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790573, Length=570, Percent_Identity=24.9122807017544, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI221142684, Length=380, Percent_Identity=27.3684210526316, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082193, Length=581, Percent_Identity=23.407917383821, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786909, Length=605, Percent_Identity=23.9669421487603, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 54122; Mature: 54122

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPL
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCC
DDLHHPKGMIKEAQDLAAAAFGADHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKS
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHH
VMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEEHSDAKGLLVINPTYFGFAAD
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHCHHHH
LEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSIL
HHHHHHHHHCCCCCEEEECCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHH
NVKEGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INDIEHLYCPGKETLGTDATFNYDPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLY
HHHHHHEECCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEHHHHC
NILCLVTFGDTESETNTLIAALQDLSATFKNKADKGVQVQVEIPEIPVLALSPRDAFYSE
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCHHCCC
TEVISFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTL
CEEEEECCCCCHHHHHHHHCCCCCCCEECCCCEEECCCHHHHHHHHCCCCCCCCCCCHHH
QTLRVIKEYKPIS
HHHHHHHHCCCCC
>Mature Secondary Structure
MYRLSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPL
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCC
DDLHHPKGMIKEAQDLAAAAFGADHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKS
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHH
VMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEEHSDAKGLLVINPTYFGFAAD
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHCHHHH
LEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSIL
HHHHHHHHHCCCCCEEEECCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHH
NVKEGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INDIEHLYCPGKETLGTDATFNYDPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLY
HHHHHHEECCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEHHHHC
NILCLVTFGDTESETNTLIAALQDLSATFKNKADKGVQVQVEIPEIPVLALSPRDAFYSE
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCHHCCC
TEVISFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTL
CEEEEECCCCCHHHHHHHHCCCCCCCEECCCCEEECCCHHHHHHHHCCCCCCCCCCCHHH
QTLRVIKEYKPIS
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]