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The map label for this gene is mtnB [H]

Identifier: 52141453

GI number: 52141453

Start: 3931500

End: 3932138

Strand: Direct

Name: mtnB [H]

Synonym: BCZK3795

Alternate gene names: 52141453

Gene position: 3931500-3932138 (Clockwise)

Preceding gene: 52141454

Following gene: 52141452

Centisome position: 74.17

GC content: 36.78

Gene sequence:

>639_bases
ATGAAACAACTTTTTCGTCAATGGTATGACTTAAGCGAGATAAAAAAAGAATTAACAACACGAAATTGGTTTCCAGCAAC
GAGTGGTAATATTTCTATAAAGGTTAGTCATGAACCACTCACTTTTCTCATTACAGCAAGTGGTAAAGATAAAACCAAAA
CGACTCCAGATGACTTTCTACTAGTAGATCATCTAGGGGTTCCCGTATTAGAGACTGAATTACGTCCCTCAGCAGAAACA
ATCTTGCATACACATATTTATAACAATACGAATGCTGGGTGCGTCCTTCATATTCATACAACTGATAACAATGTCATCAC
AAATTTATATAGTGATGCCGTCACACTTCAAAATCAAGAAATTATTAAAGCTCTCGATATTTGGGAAGAAGGTGCAACAA
TTCACATTCCTATTATCGAAAACCATGCTCATATCCCAACGCTTGGAGAAAACTTCCGCAAGCATATACAGGGAGATTCG
GGGGCAGTATTAATCCGTAACCATGGTATTACCGTATGGGGCCGAGATAGCTTTGATGCAAAGAAAAGATTAGAAGCTTA
TGAGTTTTTATTCCAATTTCATATAAAACTACTATCAATTCAAGGAGGCGTTTCTAATGGCGCAAATTCGTATTCATGA

Upstream 100 bases:

>100_bases
TCCTTATTACAAAATGCGAAGAAAATCATATTTCTTATACACCATTTGAAACGTTTCACGATGTTCAAACTGAATTAAAA
CATTTGTTGGGGGTGAAATT

Downstream 100 bases:

>100_bases
AGTAAATACTCGCATTGAAAATGAAGTGGAAGTATCTAAATTTCTACAAGAGGAAGGTGTTTTATATGAGAAATGGAATA
TTTCTAAACTTCCTCCTCAT

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAET
ILHTHIYNNTNAGCVLHIHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDS
GAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS

Sequences:

>Translated_212_residues
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAET
ILHTHIYNNTNAGCVLHIHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDS
GAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
>Mature_212_residues
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAET
ILHTHIYNNTNAGCVLHIHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDS
GAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily [H]

Homologues:

Organism=Homo sapiens, GI166235186, Length=205, Percent_Identity=28.2926829268293, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322484, Length=208, Percent_Identity=31.25, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859685, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR017714 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.2.1.109 [H]

Molecular weight: Translated: 23925; Mature: 23925

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFL
CHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEE
LVDHLGVPVLETELRPSAETILHTHIYNNTNAGCVLHIHTTDNNVITNLYSDAVTLQNQE
EEECCCCCEEECCCCCCHHHEEEEEEECCCCCCEEEEEEECCCCEEEHHHHCEEEECCHH
IIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDA
HHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCH
KKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFL
CHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEE
LVDHLGVPVLETELRPSAETILHTHIYNNTNAGCVLHIHTTDNNVITNLYSDAVTLQNQE
EEECCCCCEEECCCCCCHHHEEEEEEECCCCCCEEEEEEECCCCEEEHHHHCEEEECCHH
IIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDA
HHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCH
KKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA