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The map label for this gene is ribD [H]

Identifier: 52141386

GI number: 52141386

Start: 3991861

End: 3992973

Strand: Direct

Name: ribD [H]

Synonym: BCZK3865

Alternate gene names: 52141386

Gene position: 3991861-3992973 (Clockwise)

Preceding gene: 52141384

Following gene: 52141382

Centisome position: 75.31

GC content: 39.08

Gene sequence:

>1113_bases
ATGACAGATCAAGAATATATGAGGATTGCCCTGCAATTAGCAGAAGGAACATGTGGGCAAACAAGTCCAAATCCTATGGT
TGGTGCTATTGTTGTAAAAGACGGAAACATCGTCGGTATGGGGGCTCATTTACGTGCTGGTGAAGAACACGCAGAAGTTC
ATGCTCTTCATATGGCTGGTGACAAAGCAAAAGGAGCCACCGTGTATGTAACCCTTGAACCATGTAGCCATTTTGGAAAA
ACACCACCTTGCTGTGATTTGCTCATAAAAAAAGGAATCACACGGGTTGTAATTGCTACTCTTGATTGCAATCCGCTCGT
TTCTGGTAATGGAAAAAGAAAATTAGAGGAAGCTGGCATCGAAGTAACTACCGGTGTTCTGGAAGCAGAAGCAGTTTTAT
TAAATCGCTACTTTTTTCACTACATGAAAACGAAACGTCCATTTGTAACAATAAAAACAGCGATGAGCTTAGACGGAAAA
ACAGCAACTGTTACTGGTGAAAGTAAGTGGATTACAGGTGAAAAAGCACGAGCTGATGTTCACCAATACCGCCATACACA
TGATGCGATTCTCGTTGGAGTGAATACAGTTATAGCTGATAATCCGCATTTAACAACAAGAATTCCTAACGGGGGGCAAA
ATCCTATACGAGTTATTTTAGATACCCATTTACGAACGCCACCATCTTCTCATGTCATAACAGATGGTTTAGCACCGACA
TGGATTATAGTTGGCAGGGATGTAAATAAAGAGAAAATAGCTTCTTATGAATCTGAAAATATAACGATATTCCAAATGAA
AACGAAACAGATTGAAATACAGGATGTTTTACACTTACTCGGCGAAAAACAAATTCTTTCTCTTTTCGTCGAAGGGGGGC
AAACAGTTCATGCAAGCTTCTTACAAACAAAGTATTTCAATGAAATTATAACTTATATAAGTCCAAAATTAATTGGTGGA
AGTAAGGCCCCTACTTTATTTGGCGGAAATGGTTTTTCAACATTACAAGATGCGCTTTCCTTGGAAATTCAAGAGATGAA
ACAAATTGGTGATGATATAAAAATCGTTGCGCATGCCCGAAACGAGGTGACGAAATGTTTACAGGAATTGTAG

Upstream 100 bases:

>100_bases
CTTTCGTATTCGAACTATATTTCTAGAAATCACGTCTCCCAAACCCCAAGGATATTAAAATCCTTGGGGTTTTTTGATTT
TTTTAGGAGAGGTGAAGAAA

Downstream 100 bases:

>100_bases
AAGAATTAGGAACGATAACAAATATGCAACAAAGCGGAGAAGCAATGAAGTTAACGATACATGCCAATAAAATTTTATCA
GATGTTCACTTAGGTGATAG

Product: riboflavin biosynthesis protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTDQEYMRIALQLAEGTCGQTSPNPMVGAIVVKDGNIVGMGAHLRAGEEHAEVHALHMAGDKAKGATVYVTLEPCSHFGK
TPPCCDLLIKKGITRVVIATLDCNPLVSGNGKRKLEEAGIEVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGK
TATVTGESKWITGEKARADVHQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDGLAPT
WIIVGRDVNKEKIASYESENITIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASFLQTKYFNEIITYISPKLIGG
SKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHARNEVTKCLQEL

Sequences:

>Translated_370_residues
MTDQEYMRIALQLAEGTCGQTSPNPMVGAIVVKDGNIVGMGAHLRAGEEHAEVHALHMAGDKAKGATVYVTLEPCSHFGK
TPPCCDLLIKKGITRVVIATLDCNPLVSGNGKRKLEEAGIEVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGK
TATVTGESKWITGEKARADVHQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDGLAPT
WIIVGRDVNKEKIASYESENITIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASFLQTKYFNEIITYISPKLIGG
SKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHARNEVTKCLQEL
>Mature_369_residues
TDQEYMRIALQLAEGTCGQTSPNPMVGAIVVKDGNIVGMGAHLRAGEEHAEVHALHMAGDKAKGATVYVTLEPCSHFGKT
PPCCDLLIKKGITRVVIATLDCNPLVSGNGKRKLEEAGIEVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGKT
ATVTGESKWITGEKARADVHQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDGLAPTW
IIVGRDVNKEKIASYESENITIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASFLQTKYFNEIITYISPKLIGGS
KAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHARNEVTKCLQEL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=365, Percent_Identity=42.7397260273973, Blast_Score=283, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6319629, Length=185, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40468; Mature: 40337

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQEYMRIALQLAEGTCGQTSPNPMVGAIVVKDGNIVGMGAHLRAGEEHAEVHALHMAG
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCHHEEEEEEECC
DKAKGATVYVTLEPCSHFGKTPPCCDLLIKKGITRVVIATLDCNPLVSGNGKRKLEEAGI
CCCCCCEEEEEECCHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHCCC
EVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGKTATVTGESKWITGEKARADV
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCEEECCCHHHHHH
HQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDGLAPT
HHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEECCCCCE
WIIVGRDVNKEKIASYESENITIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASF
EEEEECCCCHHHHHCCCCCCEEEEEEECCEEEHHHHHHHHCCHHHHHHHHCCCCEEHHHH
LQTKYFNEIITYISPKLIGGSKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHAR
HHHHHHHHHHHHHCCHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
NEVTKCLQEL
HHHHHHHHHC
>Mature Secondary Structure 
TDQEYMRIALQLAEGTCGQTSPNPMVGAIVVKDGNIVGMGAHLRAGEEHAEVHALHMAG
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCHHEEEEEEECC
DKAKGATVYVTLEPCSHFGKTPPCCDLLIKKGITRVVIATLDCNPLVSGNGKRKLEEAGI
CCCCCCEEEEEECCHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHCCC
EVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGKTATVTGESKWITGEKARADV
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCEEECCCHHHHHH
HQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDGLAPT
HHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEECCCCCE
WIIVGRDVNKEKIASYESENITIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASF
EEEEECCCCHHHHHCCCCCCEEEEEEECCEEEHHHHHHHHCCHHHHHHHHCCCCEEHHHH
LQTKYFNEIITYISPKLIGGSKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHAR
HHHHHHHHHHHHHCCHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
NEVTKCLQEL
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]