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The map label for this gene is fhuG [H]

Identifier: 52141138

GI number: 52141138

Start: 4217431

End: 4218468

Strand: Reverse

Name: fhuG [H]

Synonym: BCZK4112

Alternate gene names: 52141138

Gene position: 4218468-4217431 (Counterclockwise)

Preceding gene: 52141137

Following gene: 52141140

Centisome position: 79.58

GC content: 39.21

Gene sequence:

>1038_bases
ATGATAAGTATGGAAAGTAGTGAAGTAGTAAGGGAAGAGGAACATCCTTTTGCGAAAAAAAGATGGATCATAGCAGTTAG
TTTAGTTATATTAACGATTTTAGGTCTTTTTTACGGCCTTTTCGCAGGAAGCTTATCCTTTTCTTTACGAGATATTCTAA
CAGGGATACAAGATGAAGGGTCGACAGTTCATCGAATTGTATGGGATCTTCGTATACCAAGAGTGCTCGTTGGATTTATA
GTAGGAACATGTTTAGCTGCATCAGGTGCATTATTACAAGGAGTTATGAGAAACCCTCTTGCAGACCCCGGTATTATTGG
GGTTTCATCTGGAGCAGGCCTTGTAGCAATCGTAATTATGATTTTATTCCCTCAGCATATGGCTTTTTTACCGCTCGGGG
CATTTTTAGGAGCTCTCATAACGGCGATGATCATTTATGCTTTATCATGGCAAAAAGGGGCGCCACCTTCAAGAATTGTC
TTAGTAGGCGTGTCAATCAATGCATTAATTGGTGCAGCGACATCAGCGTTAATGTTATTGCATAGTGACAAAGTACAGTC
CGTGTTACCGTGGTTAGCAGGTGGCATTGGTGGTGTGAGCTGGGCACATTTAAACATGATTATTTATTATGCAGTATTCG
CTATTATATTGGCTTTCTTTAGTATCAAGCATATTCGAGTATTAATGCTTGGAGATGAAATGGCGAAATTATTAGGTCAT
AACGTGGAGAGAAGCCGGTTTTATTTAATAGTAGTAAGTACATTATTAGCTGGAATTGCGGTTAGTGTTTCTGGTCTTAT
TGGATTTGTCGGTCTCGTCGTACCACATATGTTACGTTTATTAGTTGGGAATGACTATAAATATTTATTACCATTATCAT
GCCTTGGCGGAGGCATATTACTTGTTTTCGCGGATGCGATAGCTCGAAGTTGGTTCGATCCAATTGAATTACCTGTCGGT
ATTTTATTATCCTTCTTAGGCGGTCCGTTCTTCTTATATTTAATTCATAGAGGAGGCAAGCAACGTGATTTCCGTTAA

Upstream 100 bases:

>100_bases
GTGTAGTTATTTTGCCACCTGACTTATTTGGATCAAATCCTGGAACAAAAGTTACAGAAGCGATGGACTTTATGTATAAA
AGTATACAAGATGTAAGGAA

Downstream 100 bases:

>100_bases
CAAAGTGTTTTACGCACATTCCGAAAGATTTCAAATGCAAAATATGAATGTACATATTAAAGCTGGAGAGGTCGTTAGTT
TAATTGGACCGAATGGGTCA

Product: iron compound ABC transporter, permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MISMESSEVVREEEHPFAKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVLVGFI
VGTCLAASGALLQGVMRNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFLGALITAMIIYALSWQKGAPPSRIV
LVGVSINALIGAATSALMLLHSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAVFAIILAFFSIKHIRVLMLGDEMAKLLGH
NVERSRFYLIVVSTLLAGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIELPVG
ILLSFLGGPFFLYLIHRGGKQRDFR

Sequences:

>Translated_345_residues
MISMESSEVVREEEHPFAKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVLVGFI
VGTCLAASGALLQGVMRNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFLGALITAMIIYALSWQKGAPPSRIV
LVGVSINALIGAATSALMLLHSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAVFAIILAFFSIKHIRVLMLGDEMAKLLGH
NVERSRFYLIVVSTLLAGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIELPVG
ILLSFLGGPFFLYLIHRGGKQRDFR
>Mature_345_residues
MISMESSEVVREEEHPFAKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVLVGFI
VGTCLAASGALLQGVMRNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFLGALITAMIIYALSWQKGAPPSRIV
LVGVSINALIGAATSALMLLHSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAVFAIILAFFSIKHIRVLMLGDEMAKLLGH
NVERSRFYLIVVSTLLAGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIELPVG
ILLSFLGGPFFLYLIHRGGKQRDFR

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=319, Percent_Identity=34.7962382445141, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786804, Length=327, Percent_Identity=29.6636085626911, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790741, Length=318, Percent_Identity=31.4465408805031, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788004, Length=277, Percent_Identity=34.2960288808664, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1786805, Length=275, Percent_Identity=36, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1786347, Length=279, Percent_Identity=30.4659498207885, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37229; Mature: 37229

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISMESSEVVREEEHPFAKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEG
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
STVHRIVWDLRIPRVLVGFIVGTCLAASGALLQGVMRNPLADPGIIGVSSGAGLVAIVIM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
ILFPQHMAFLPLGAFLGALITAMIIYALSWQKGAPPSRIVLVGVSINALIGAATSALMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
HSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAVFAIILAFFSIKHIRVLMLGDEMAKLLGH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCC
NVERSRFYLIVVSTLLAGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCHHH
LVFADAIARSWFDPIELPVGILLSFLGGPFFLYLIHRGGKQRDFR
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISMESSEVVREEEHPFAKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEG
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
STVHRIVWDLRIPRVLVGFIVGTCLAASGALLQGVMRNPLADPGIIGVSSGAGLVAIVIM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
ILFPQHMAFLPLGAFLGALITAMIIYALSWQKGAPPSRIVLVGVSINALIGAATSALMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
HSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAVFAIILAFFSIKHIRVLMLGDEMAKLLGH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCC
NVERSRFYLIVVSTLLAGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCHHH
LVFADAIARSWFDPIELPVGILLSFLGGPFFLYLIHRGGKQRDFR
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]