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The map label for this gene is nadA [H]

Identifier: 52141077

GI number: 52141077

Start: 4279772

End: 4280878

Strand: Reverse

Name: nadA [H]

Synonym: BCZK4173

Alternate gene names: 52141077

Gene position: 4280878-4279772 (Counterclockwise)

Preceding gene: 52141076

Following gene: 52141078

Centisome position: 80.76

GC content: 38.3

Gene sequence:

>1107_bases
ATGAGTATTTTAGAAAAAGTACAACCGATTGAAACGATGTTACCAGAGCGTTATTACACGATGTCAACAGAAGATATGGA
AAAGCGGGTTCGTGAAATTAAAGAAAAAATGGGGGAAACGCTATTTATTCCAGGACATCATTACCAAAAAGATGAAGTGG
TACAATTTTCTGATGCGGCAGGAGATTCACTTCAGCTTGCGCAAGTTGCAGCGAGCAATAAAGACGCAAAATATATTGTA
TTTTGCGGTGTACACTTTATGGCAGAAACAGCAGATATGTTAACGACAGATGATCAAATTGTTATTTTGCCAGATATGCG
TGCAGGGTGTTCGATGGCAGATATGGCAGATATAGAACAAACAGAAAGAGCGTGGAAAGAGCTCACAAAATTATTTGGAG
ATACGATGATTCCGTTAACGTATGTGAACTCTACAGCTGCCATTAAAGCGTTTTGTGGTCGTAATGGCGGAGCAACAGTA
ACGTCTTCTAATGCAAAACAAATGGTATCTTGGGCTTTTACGCAAAAAGAGCGTCTCGTCTTTTTACCGGATCAACATCT
AGGGAGAAATACAGCGTACGACTTAGGTATACCGTTAGATAAAATGGCAGTATGGGACCCGCATACTGATTCATTAGAGT
ACGATGGAGATATAGAAGAAATCCAAGTGATTTTATGGAAAGGTCATTGTTCAGTTCATCAAAACTTTACAGTGAAAAAC
ATAGAGAATGTACGGAAAAATCATCCGGATATGAATATTATTGTACATCCGGAATGTTGCTATGAAGTTGTAGCTGCTTC
GGATTATGCAGGTTCAACGAAATACATTATTGATATGATTGAATCGGCTCCATCCGGAAGTAAATGGGCGATTGGTACAG
AAATGAATTTAGTGAACCGAATTATTCAACAACACCCAGATAAAGAAATTGTTTCACTTAATCCGTTTATGTGTCCATGT
TTAACGATGAACCGAATTGATTTGCCGCACTTATTATGGGCACTTGAAACGATAGAAAGAGGAGAAGAAATTAACGTTAT
TAGCGTAGATAAACAAGTAACTGAAGAAGCGGTTCTTGCATTAAATCGTATGTTAGAGCGTGTGTGA

Upstream 100 bases:

>100_bases
TTATATTTCACTTGGAGCGTTAACACATTCAGTGAAAGCACTTGATATTAGTTTCAATATTGAGGCGTAAGGAAAGTGGC
TTAGAGGGGGAGAAAGAAAT

Downstream 100 bases:

>100_bases
AGCAGCGGGATTCCCGTTGCTTTTTTTCATACATGTAATCATAACGAGAACGAAATGGGCATACATTGTTTTGAAGAAAT
CATTGTGATTTTTTTATGCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKDAKYIV
FCGVHFMAETADMLTTDDQIVILPDMRAGCSMADMADIEQTERAWKELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATV
TSSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPC
LTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV

Sequences:

>Translated_368_residues
MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKDAKYIV
FCGVHFMAETADMLTTDDQIVILPDMRAGCSMADMADIEQTERAWKELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATV
TSSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPC
LTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV
>Mature_367_residues
SILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKDAKYIVF
CGVHFMAETADMLTTDDQIVILPDMRAGCSMADMADIEQTERAWKELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVT
SSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKNI
ENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPCL
TMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=354, Percent_Identity=27.1186440677966, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 41611; Mature: 41480

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAA
CCHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCC
GDSLQLAQVAASNKDAKYIVFCGVHFMAETADMLTTDDQIVILPDMRAGCSMADMADIEQ
CCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TERAWKELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKQMVSWAFTQKERLV
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCEE
FLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
ECCCHHCCCCCCEECCCCHHHEEEECCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCHHH
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNR
HHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHH
IIQQHPDKEIVSLNPFMCPCLTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLA
HHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
LNRMLERV
HHHHHHCC
>Mature Secondary Structure 
SILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAA
CHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCC
GDSLQLAQVAASNKDAKYIVFCGVHFMAETADMLTTDDQIVILPDMRAGCSMADMADIEQ
CCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TERAWKELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKQMVSWAFTQKERLV
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCEE
FLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKN
ECCCHHCCCCCCEECCCCHHHEEEECCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCHHH
IENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNR
HHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHH
IIQQHPDKEIVSLNPFMCPCLTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLA
HHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
LNRMLERV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA