Click here to switch to the map view.

The map label for this gene is lytS [H]

Identifier: 52141002

GI number: 52141002

Start: 4359601

End: 4360374

Strand: Direct

Name: lytS [H]

Synonym: BCZK4248

Alternate gene names: 52141002

Gene position: 4359601-4360374 (Clockwise)

Preceding gene: 52141003

Following gene: 52141001

Centisome position: 82.24

GC content: 31.78

Gene sequence:

>774_bases
ATGTTAACTTATGAAGCATTTGCTGTATTAATAACTATACTTGTCTTAGCTCCAATTTTTGGAGCTATTATTTTATTATG
TTTATTTATTTTTGAAAAACGAATCGACTTACTAGAAAGTGAGAAGAAAAAAATAGCACTAGAAAGAGAGTTGCAACAGT
CTTTATATCATCAACTCACTCAACAAATTCAGCCTCATTTTTTATTCAATACATTAAATACAATTTTAAGCTTAGCCCGT
TTGCAAAGAACAGATGAAGTTGTCCGATCGCTCGAGATCTTTTCTCTATTTTTAAAAGGAAAATATAAAACAACAGATTT
GTTAATTCCTATTTCTGAAGAACTAGCGTATACAAATTATTATATTGAGATTCAAAAAATGCGGTTTCGCTCGAGGCTTT
CAGTAAGCATTACCTCTTCTGAAGATTTACACAATGCCCATATTCCACCTTTCGTTATTCAAACGTTAGTGGAGAATTCC
TTTAAACATGGTCTTGAAAAAAAAGCTGGTCAAGCAATTTTAAATATTCATTTATACAATACAAATAACCGAATTACACT
TCTAGTATCCGACAACGGTACTCAAAATGAACCATTTACTTCCTATACAGAAGAAAGCGGATACGGACTTGAGAATATAA
AACAACGATTTCAACTATTCTTTCAAGAACAAACTACGTTCTCTTTCCTCTCTACAAAAGAGAACGGCACAACAGTAGAA
ATAACATGGCCTTTCATCACAGAAAAAAACACAGAGGAGGTAATACAAAAATGA

Upstream 100 bases:

>100_bases
AGATCATAAAGTAGCCTGTCATATTATTTAATGCGAGTCTGAATAATAGAAATATTTACAACACTTTAGTATAATAATAA
AAAACAAGATTGAGGTATGT

Downstream 100 bases:

>100_bases
ATGTGCTATTAGTAGATGACGAGCCGCTAGAACTGGAACAATTAGAGTTTCTCATTCACCGCCAGTTTCCTAATTGGACA
TTACATCTAGCTTTAGATGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLTQQIQPHFLFNTLNTILSLAR
LQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNYYIEIQKMRFRSRLSVSITSSEDLHNAHIPPFVIQTLVENS
FKHGLEKKAGQAILNIHLYNTNNRITLLVSDNGTQNEPFTSYTEESGYGLENIKQRFQLFFQEQTTFSFLSTKENGTTVE
ITWPFITEKNTEEVIQK

Sequences:

>Translated_257_residues
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLTQQIQPHFLFNTLNTILSLAR
LQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNYYIEIQKMRFRSRLSVSITSSEDLHNAHIPPFVIQTLVENS
FKHGLEKKAGQAILNIHLYNTNNRITLLVSDNGTQNEPFTSYTEESGYGLENIKQRFQLFFQEQTTFSFLSTKENGTTVE
ITWPFITEKNTEEVIQK
>Mature_257_residues
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLTQQIQPHFLFNTLNTILSLAR
LQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNYYIEIQKMRFRSRLSVSITSSEDLHNAHIPPFVIQTLVENS
FKHGLEKKAGQAILNIHLYNTNNRITLLVSDNGTQNEPFTSYTEESGYGLENIKQRFQLFFQEQTTFSFLSTKENGTTVE
ITWPFITEKNTEEVIQK

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=198, Percent_Identity=28.2828282828283, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788723, Length=174, Percent_Identity=34.4827586206897, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 29852; Mature: 29852

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIQPHFLFNTLNTILSLARLQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNY
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
YIEIQKMRFRSRLSVSITSSEDLHNAHIPPFVIQTLVENSFKHGLEKKAGQAILNIHLYN
EEEEHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
TNNRITLLVSDNGTQNEPFTSYTEESGYGLENIKQRFQLFFQEQTTFSFLSTKENGTTVE
CCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCEEE
ITWPFITEKNTEEVIQK
EEECEECCCCHHHHHCC
>Mature Secondary Structure
MLTYEAFAVLITILVLAPIFGAIILLCLFIFEKRIDLLESEKKKIALERELQQSLYHQLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQIQPHFLFNTLNTILSLARLQRTDEVVRSLEIFSLFLKGKYKTTDLLIPISEELAYTNY
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
YIEIQKMRFRSRLSVSITSSEDLHNAHIPPFVIQTLVENSFKHGLEKKAGQAILNIHLYN
EEEEHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
TNNRITLLVSDNGTQNEPFTSYTEESGYGLENIKQRFQLFFQEQTTFSFLSTKENGTTVE
CCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCEEE
ITWPFITEKNTEEVIQK
EEECEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]