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The map label for this gene is emrA [H]

Identifier: 52140939

GI number: 52140939

Start: 4424542

End: 4425195

Strand: Reverse

Name: emrA [H]

Synonym: BCZK4311

Alternate gene names: 52140939

Gene position: 4425195-4424542 (Counterclockwise)

Preceding gene: 52140937

Following gene: 52140940

Centisome position: 83.48

GC content: 36.54

Gene sequence:

>654_bases
ATGAATCAGTTTCGAAGAATGGTGATTATCAACATTATCACATTAATTGTACTAGTTGGCGGCGGTATTGGCGGTTATTA
CTATTACAATCAAGCGGAAAATTACTTAAAAACAGACAATGCAAAAATTGATGGAAAGGTAATTCCAATTGCATCACCAG
TAGCAGGGAAATTAACTGACTGGAAAGCTGAAGTAGGTAAGAACTACAACGAGAATGATAAATTAGGTGCTGTCACTGTA
GCAGCAGCGAATGGAGAACAAACAGTAGATGTAACAATTCCACAAAATGCAACAGTTGTACAATCAAACGCGACAACAAA
TGCTTTCGTTGGAGCAGGTAGCCCGATTGCTTATGCATTTGATATGAACAATTTATGGGTAACAGCAAATATTGAAGAAA
CAGATGTTGATGATGTTCAAAAAGGTCAAGATGTAGATGTGTATGTAGATGCATACCCAGATACAACGTTAACAGGAAAA
GTAGAACAAGTGGGCTTAACAACAGCGAACACATTCTCTATGTTACCATCAAGCAACGCAACAGCAAACTATACGAAAGT
AACACAAGTAGTACCAGTTAAAATTTCTTTAGATCATAGCAAATCAGTAAATATTGTTCCTGGCATGAATGTGACAGTTC
GTATTCATAAGTAA

Upstream 100 bases:

>100_bases
TTTGTTTAAAAGTTAATATAATTAACAATTAAATAGTCTAAACAATAAGGACGTAAATAGTTTAGAAAAAAATTATATGC
GATATAAGGAGAGGAATGCA

Downstream 100 bases:

>100_bases
GGGGGAGATGAGATGTCCTCAATCGTAATTGCAGGATATGCACTATTTTGTATAATCGTCTTCTTCCTTGTAAATCGTCT
TTTACGAAAGAAAAAAACGA

Product: multidrug resistance protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNQFRRMVIINIITLIVLVGGGIGGYYYYNQAENYLKTDNAKIDGKVIPIASPVAGKLTDWKAEVGKNYNENDKLGAVTV
AAANGEQTVDVTIPQNATVVQSNATTNAFVGAGSPIAYAFDMNNLWVTANIEETDVDDVQKGQDVDVYVDAYPDTTLTGK
VEQVGLTTANTFSMLPSSNATANYTKVTQVVPVKISLDHSKSVNIVPGMNVTVRIHK

Sequences:

>Translated_217_residues
MNQFRRMVIINIITLIVLVGGGIGGYYYYNQAENYLKTDNAKIDGKVIPIASPVAGKLTDWKAEVGKNYNENDKLGAVTV
AAANGEQTVDVTIPQNATVVQSNATTNAFVGAGSPIAYAFDMNNLWVTANIEETDVDDVQKGQDVDVYVDAYPDTTLTGK
VEQVGLTTANTFSMLPSSNATANYTKVTQVVPVKISLDHSKSVNIVPGMNVTVRIHK
>Mature_217_residues
MNQFRRMVIINIITLIVLVGGGIGGYYYYNQAENYLKTDNAKIDGKVIPIASPVAGKLTDWKAEVGKNYNENDKLGAVTV
AAANGEQTVDVTIPQNATVVQSNATTNAFVGAGSPIAYAFDMNNLWVTANIEETDVDDVQKGQDVDVYVDAYPDTTLTGK
VEQVGLTTANTFSMLPSSNATANYTKVTQVVPVKISLDHSKSVNIVPGMNVTVRIHK

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=110, Percent_Identity=34.5454545454545, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789041, Length=109, Percent_Identity=34.8623853211009, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000089
- InterPro:   IPR006143
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 23349; Mature: 23349

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFRRMVIINIITLIVLVGGGIGGYYYYNQAENYLKTDNAKIDGKVIPIASPVAGKLTD
CCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCEECCEEEEECCCCCCCCCC
WKAEVGKNYNENDKLGAVTVAAANGEQTVDVTIPQNATVVQSNATTNAFVGAGSPIAYAF
CHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCEEEECCCCCEEEEECCCCEEEEE
DMNNLWVTANIEETDVDDVQKGQDVDVYVDAYPDTTLTGKVEQVGLTTANTFSMLPSSNA
ECCCEEEEEECCCCCCCHHHCCCCEEEEEECCCCCEECCCEEEEECEECCEEEECCCCCC
TANYTKVTQVVPVKISLDHSKSVNIVPGMNVTVRIHK
CCCEEEEEEEEEEEEEECCCCCEEEECCCEEEEEEEC
>Mature Secondary Structure
MNQFRRMVIINIITLIVLVGGGIGGYYYYNQAENYLKTDNAKIDGKVIPIASPVAGKLTD
CCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCEECCEEEEECCCCCCCCCC
WKAEVGKNYNENDKLGAVTVAAANGEQTVDVTIPQNATVVQSNATTNAFVGAGSPIAYAF
CHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCEEEECCCCCEEEEECCCCEEEEE
DMNNLWVTANIEETDVDDVQKGQDVDVYVDAYPDTTLTGKVEQVGLTTANTFSMLPSSNA
ECCCEEEEEECCCCCCCHHHCCCCEEEEEECCCCCEECCCEEEEECEECCEEEECCCCCC
TANYTKVTQVVPVKISLDHSKSVNIVPGMNVTVRIHK
CCCEEEEEEEEEEEEEECCCCCEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]