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The map label for this gene is moaE [H]

Identifier: 52140780

GI number: 52140780

Start: 4568257

End: 4568721

Strand: Reverse

Name: moaE [H]

Synonym: BCZK4470

Alternate gene names: 52140780

Gene position: 4568721-4568257 (Counterclockwise)

Preceding gene: 52140781

Following gene: 52140784

Centisome position: 86.19

GC content: 41.08

Gene sequence:

>465_bases
ATGACAAATACGTATTATGAAGTAATTGATACAGAAATTTTGGTTGAAGAGGTAGCGAAGAGAGTAATTCGCCGCGAATG
CGGTGCTGTTACAACATTTATTGGAACGGTTAGAGAGTTTACGAAAGGGCGTCGTACATTATACTTAGAATATGTCGCTT
ATAAAACGATGGCAGAAAAGATGCTAGAGAAAATCGGATCAGAAGTGAAAGAGAAATGGCCAGGTACACACGTTGCGATT
ACACATCGCATCGGTACACTGCAAATTTCTGATATTGCGGTTGTTGTGGCCGTTTCAACGCCGCATCGTAAAGCGGCTTA
TGAAGCAAATGAATATATTATGGAACGCATAAAACAAATTGTTCCGATTTGGAAAAAAGAGTTTTGGGAAGATGGAGACT
CTTGGATTGGCGATCAATTAGAAAAAACGCCATATCCGGCGGGAGAGCCTGGGAAGGAGCTATAA

Upstream 100 bases:

>100_bases
ATGATGCTCCTGCAAACTTACGAGAAGAATATAAAGTATTTCATATAACAGAAGAAAAATTGTACATAGACTGGTTTTTA
CAAACGGTAAGGAGTGCGAA

Downstream 100 bases:

>100_bases
GTATGATTCGAGTATTGTTATTTGCGAACTTACAAGAAGAAGCAGGAAGAAGTGAATTACAAATAGAGAAAGAAAGTATT
ACGGTTGCAGAGTTAAAAGA

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTNTYYEVIDTEILVEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGSEVKEKWPGTHVAI
THRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL

Sequences:

>Translated_154_residues
MTNTYYEVIDTEILVEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGSEVKEKWPGTHVAI
THRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
>Mature_153_residues
TNTYYEVIDTEILVEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKMLEKIGSEVKEKWPGTHVAIT
HRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=125, Percent_Identity=42.4, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1787003, Length=113, Percent_Identity=40.7079646017699, Blast_Score=90, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17509279, Length=128, Percent_Identity=35.15625, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356259, Length=131, Percent_Identity=36.6412213740458, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17726; Mature: 17594

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTYYEVIDTEILVEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
MLEKIGSEVKEKWPGTHVAITHRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQI
HHHHHHHHHHHHCCCCEEEEEECCCEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TNTYYEVIDTEILVEEVAKRVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
MLEKIGSEVKEKWPGTHVAITHRIGTLQISDIAVVVAVSTPHRKAAYEANEYIMERIKQI
HHHHHHHHHHHHCCCCEEEEEECCCEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGDSWIGDQLEKTPYPAGEPGKEL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]