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The map label for this gene is gntP [H]

Identifier: 52140661

GI number: 52140661

Start: 4681106

End: 4682431

Strand: Reverse

Name: gntP [H]

Synonym: BCZK4594

Alternate gene names: 52140661

Gene position: 4682431-4681106 (Counterclockwise)

Preceding gene: 52140658

Following gene: 52140660

Centisome position: 88.33

GC content: 36.88

Gene sequence:

>1326_bases
ATGGATATATACTTATTAATCGTCACGTTACTTGCAATTGCGATTGTTATTTTAGGGGTATCATGGTGGAAATGGCATGC
ATTTATTAGTTTAACAGTTGCGAGTTTATTTTTAGCTATTATGTCTGGATTGAATTTAACGAAGATAGTGACTGCCTATG
AATCTGGTGTTGGTAGTGTACTAGGGCATTTAGTTGGTATTTTAGCTCTCGGTACAATTTTAGGAAAAATGATGTCCGAT
TCAGGGGCCGGCATGCAAGTGGCAGATTTCTTTATTCGATTTTTCGGTGTGAAGAAACTACCGTGGGCTATGTTATTTGC
AGGATTTGTTATAGGGATTCCGGTATTTTTTGAAGTGGGGATTGTCATTTTATTACCACTCGTGATTTCCATTCGAAAAA
CGACGAAGCAAAATATATTATTAATTGCATTACCTGTCATTGCTGGATTATCTATTGTTCACGGGCTCGTGCCACCACAT
CCAGGAGCGATGACAGCAATCGGTATTTATAACGCGAACTTAGGAAAGGTACTTTTATATTCATTACTTATCGCGCTACC
AACAGCCATTATCGCAGGACCGATATTTGCAAAGTGGGTACATAAAAGGGTTATACCTGAAAATGAACCAGAGCTTATTC
GAGTTACGACTGTATCAACTGATTTACCGAGTCGTAAAGTTTCATTCTTTATTATTTTATTACCAGTTGTATTGATGATT
TTATCAGTCGTTGCACCATATATTTCATTACCGAAAAAGATGACTGAATTTTTTGTATTTATCGGAAGTCCAGTAATCGC
TTTACTAATTTCATGTTTTGCAGCATTTTATTTACTTGGCATGAGACAAGGTATTAATAAAAAGATGATTAAAAAATTAA
CGGATGAAAGCTTATTACCTGTCGGTTCCATTATTTTAATAATCGGCGCAGGCGGTGGCTTTAAACAAATATTAATTGAA
AGCGGCGTTGGAACGGCGATTGCGCAAATGGCAGAACATATATCGTTATCACCAATCGTATTAGCTTTCATGGTAGCTGG
ATTAATTCGAATTGCAACAGGTTCAGCAACAGTAGCATTAACGACAGCAGCAGGGATTGTTTCACCAGTTATTCAGCACA
TGTCTGGTGTGAATTTAGAAATGCTCGTTATAGCAACCGGTGCAGGCTCATTAATGTTTTCTCACGTAAATGATGCAGGG
TTCTGGCTTGTAAAAGAATATTTAGGTTTGACAGTAAAAGAAACGTTTAAAACGTGGACAGTGCTAGAGACATTGTTATC
ATTTATTGCATTCGGTTTTGCCCTTGTATTGAATATGTTTCTTTAA

Upstream 100 bases:

>100_bases
AGGGCTACTACAATACAGAAATGCAGCATTATGTAGTGAATTATGACGTATAAAAAGAGGGTATTCGCCCTCTTTTTTTA
TAAAGTAAGGGGAATGAGAG

Downstream 100 bases:

>100_bases
AAGATACCTGAATAGGTATCTTTTTTTGATGAAGCCCAATTGCCAAAACAAGCCCGTTTTTAAGTAAGCCAAGCTTCCTA
TTCGCCCTGAAAACATACTA

Product: gluconate permease

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MDIYLLIVTLLAIAIVILGVSWWKWHAFISLTVASLFLAIMSGLNLTKIVTAYESGVGSVLGHLVGILALGTILGKMMSD
SGAGMQVADFFIRFFGVKKLPWAMLFAGFVIGIPVFFEVGIVILLPLVISIRKTTKQNILLIALPVIAGLSIVHGLVPPH
PGAMTAIGIYNANLGKVLLYSLLIALPTAIIAGPIFAKWVHKRVIPENEPELIRVTTVSTDLPSRKVSFFIILLPVVLMI
LSVVAPYISLPKKMTEFFVFIGSPVIALLISCFAAFYLLGMRQGINKKMIKKLTDESLLPVGSIILIIGAGGGFKQILIE
SGVGTAIAQMAEHISLSPIVLAFMVAGLIRIATGSATVALTTAAGIVSPVIQHMSGVNLEMLVIATGAGSLMFSHVNDAG
FWLVKEYLGLTVKETFKTWTVLETLLSFIAFGFALVLNMFL

Sequences:

>Translated_441_residues
MDIYLLIVTLLAIAIVILGVSWWKWHAFISLTVASLFLAIMSGLNLTKIVTAYESGVGSVLGHLVGILALGTILGKMMSD
SGAGMQVADFFIRFFGVKKLPWAMLFAGFVIGIPVFFEVGIVILLPLVISIRKTTKQNILLIALPVIAGLSIVHGLVPPH
PGAMTAIGIYNANLGKVLLYSLLIALPTAIIAGPIFAKWVHKRVIPENEPELIRVTTVSTDLPSRKVSFFIILLPVVLMI
LSVVAPYISLPKKMTEFFVFIGSPVIALLISCFAAFYLLGMRQGINKKMIKKLTDESLLPVGSIILIIGAGGGFKQILIE
SGVGTAIAQMAEHISLSPIVLAFMVAGLIRIATGSATVALTTAAGIVSPVIQHMSGVNLEMLVIATGAGSLMFSHVNDAG
FWLVKEYLGLTVKETFKTWTVLETLLSFIAFGFALVLNMFL
>Mature_441_residues
MDIYLLIVTLLAIAIVILGVSWWKWHAFISLTVASLFLAIMSGLNLTKIVTAYESGVGSVLGHLVGILALGTILGKMMSD
SGAGMQVADFFIRFFGVKKLPWAMLFAGFVIGIPVFFEVGIVILLPLVISIRKTTKQNILLIALPVIAGLSIVHGLVPPH
PGAMTAIGIYNANLGKVLLYSLLIALPTAIIAGPIFAKWVHKRVIPENEPELIRVTTVSTDLPSRKVSFFIILLPVVLMI
LSVVAPYISLPKKMTEFFVFIGSPVIALLISCFAAFYLLGMRQGINKKMIKKLTDESLLPVGSIILIIGAGGGFKQILIE
SGVGTAIAQMAEHISLSPIVLAFMVAGLIRIATGSATVALTTAAGIVSPVIQHMSGVNLEMLVIATGAGSLMFSHVNDAG
FWLVKEYLGLTVKETFKTWTVLETLLSFIAFGFALVLNMFL

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1790716, Length=442, Percent_Identity=39.8190045248869, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI48994935, Length=439, Percent_Identity=40.5466970387244, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI2367370, Length=451, Percent_Identity=36.3636363636364, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1788707, Length=448, Percent_Identity=35.2678571428571, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1790776, Length=425, Percent_Identity=34.3529411764706, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI48994939, Length=412, Percent_Identity=39.0776699029126, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1789097, Length=391, Percent_Identity=34.2710997442455, Blast_Score=221, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47273; Mature: 47273

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIYLLIVTLLAIAIVILGVSWWKWHAFISLTVASLFLAIMSGLNLTKIVTAYESGVGSV
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGHLVGILALGTILGKMMSDSGAGMQVADFFIRFFGVKKLPWAMLFAGFVIGIPVFFEVG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IVILLPLVISIRKTTKQNILLIALPVIAGLSIVHGLVPPHPGAMTAIGIYNANLGKVLLY
HHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHH
SLLIALPTAIIAGPIFAKWVHKRVIPENEPELIRVTTVSTDLPSRKVSFFIILLPVVLMI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
LSVVAPYISLPKKMTEFFVFIGSPVIALLISCFAAFYLLGMRQGINKKMIKKLTDESLLP
HHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
VGSIILIIGAGGGFKQILIESGVGTAIAQMAEHISLSPIVLAFMVAGLIRIATGSATVAL
CCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEE
TTAAGIVSPVIQHMSGVNLEMLVIATGAGSLMFSHVNDAGFWLVKEYLGLTVKETFKTWT
HHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
VLETLLSFIAFGFALVLNMFL
HHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDIYLLIVTLLAIAIVILGVSWWKWHAFISLTVASLFLAIMSGLNLTKIVTAYESGVGSV
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGHLVGILALGTILGKMMSDSGAGMQVADFFIRFFGVKKLPWAMLFAGFVIGIPVFFEVG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IVILLPLVISIRKTTKQNILLIALPVIAGLSIVHGLVPPHPGAMTAIGIYNANLGKVLLY
HHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHH
SLLIALPTAIIAGPIFAKWVHKRVIPENEPELIRVTTVSTDLPSRKVSFFIILLPVVLMI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
LSVVAPYISLPKKMTEFFVFIGSPVIALLISCFAAFYLLGMRQGINKKMIKKLTDESLLP
HHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
VGSIILIIGAGGGFKQILIESGVGTAIAQMAEHISLSPIVLAFMVAGLIRIATGSATVAL
CCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEE
TTAAGIVSPVIQHMSGVNLEMLVIATGAGSLMFSHVNDAGFWLVKEYLGLTVKETFKTWT
HHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
VLETLLSFIAFGFALVLNMFL
HHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]