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The map label for this gene is comA [H]

Identifier: 52140609

GI number: 52140609

Start: 4745549

End: 4745932

Strand: Reverse

Name: comA [H]

Synonym: BCZK4647

Alternate gene names: 52140609

Gene position: 4745932-4745549 (Counterclockwise)

Preceding gene: 52140606

Following gene: 52140611

Centisome position: 89.53

GC content: 38.02

Gene sequence:

>384_bases
ATGGCAAAAACTTTAATGGATTCACTTGGAATTGAGTTGTTAGAGATGACAGAAGATAAGGTAGTTGCTACGATGCCTGT
TGATGAACGTACACATCAGCCGTTTGGTTTTTTACACGGTGGTGCATCTCTTGCGTTAGCAGAAACAGTAGCAAGCGTCG
GTTCATACAATTTAATTGATCAAGAGAAATGCATTTGCTTCGGTCTAGAAATTAATGCAAACCATATTCGCTCAAAGAAA
GATGGAATGGTAACAGCAATCGGAACACCGATACATAGAGGACATTCAACGATGGTTTGGGATGTGCGCATCATTGATGA
GAATGACGATTTATTATGTATTTCAAGATGTACAGTAGCAATTAAAGAAAAACGTGAAAAGTAA

Upstream 100 bases:

>100_bases
TTCATTTAGGTGAAACCTCCTTATATAAGTGTTATACGTAGTTTGAAAGTAAATAGGTAAAATTATACATTTAATTAAAG
TGAGAGAAGGGGGAAACGAT

Downstream 100 bases:

>100_bases
AAAAGAGGCGGCTCAATAGAGCGCCTCTTTTTTATAATTAGAACTGGATTTTCTTCTCTAAGAAACCTTTTAGTTCGCTA
ATTGGCATACGAACTTGTTC

Product: comA operon protein (competence protein)

Products: NA

Alternate protein names: ComA operon protein 2 [H]

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MAKTLMDSLGIELLEMTEDKVVATMPVDERTHQPFGFLHGGASLALAETVASVGSYNLIDQEKCICFGLEINANHIRSKK
DGMVTAIGTPIHRGHSTMVWDVRIIDENDDLLCISRCTVAIKEKREK

Sequences:

>Translated_127_residues
MAKTLMDSLGIELLEMTEDKVVATMPVDERTHQPFGFLHGGASLALAETVASVGSYNLIDQEKCICFGLEINANHIRSKK
DGMVTAIGTPIHRGHSTMVWDVRIIDENDDLLCISRCTVAIKEKREK
>Mature_126_residues
AKTLMDSLGIELLEMTEDKVVATMPVDERTHQPFGFLHGGASLALAETVASVGSYNLIDQEKCICFGLEINANHIRSKKD
GMVTAIGTPIHRGHSTMVWDVRIIDENDDLLCISRCTVAIKEKREK

Specific function: Is not required for competence [H]

COG id: COG2050

COG function: function code Q; Uncharacterized protein, possibly involved in aromatic compounds catabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase PaaI family [H]

Homologues:

Organism=Escherichia coli, GI1787976, Length=118, Percent_Identity=46.6101694915254, Blast_Score=110, Evalue=3e-26,
Organism=Escherichia coli, GI1786813, Length=119, Percent_Identity=39.4957983193277, Blast_Score=97, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003736
- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: NA

Molecular weight: Translated: 14042; Mature: 13911

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTLMDSLGIELLEMTEDKVVATMPVDERTHQPFGFLHGGASLALAETVASVGSYNLID
CCCHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCC
QEKCICFGLEINANHIRSKKDGMVTAIGTPIHRGHSTMVWDVRIIDENDDLLCISRCTVA
CCCEEEEEEEECHHHCCCCCCCEEEEECCCEECCCCEEEEEEEEEECCCCEEEEEHHHEE
IKEKREK
EHHCCCC
>Mature Secondary Structure 
AKTLMDSLGIELLEMTEDKVVATMPVDERTHQPFGFLHGGASLALAETVASVGSYNLID
CCHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCC
QEKCICFGLEINANHIRSKKDGMVTAIGTPIHRGHSTMVWDVRIIDENDDLLCISRCTVA
CCCEEEEEEEECHHHCCCCCCCEEEEECCCEECCCCEEEEEEEEEECCCCEEEEEHHHEE
IKEKREK
EHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2507523; 9274030; 9384377 [H]