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The map label for this gene is gtaB [H]

Identifier: 52140606

GI number: 52140606

Start: 4747461

End: 4748348

Strand: Reverse

Name: gtaB [H]

Synonym: BCZK4650

Alternate gene names: 52140606

Gene position: 4748348-4747461 (Counterclockwise)

Preceding gene: 52140605

Following gene: 52140609

Centisome position: 89.58

GC content: 37.5

Gene sequence:

>888_bases
ATGAAAAGAGTAAGAAAAGCGATAATCCCAGCAGCTGGATTAGGAACACGTTTTTTACCAGCTACAAAAGCAATGCCAAA
AGAAATGTTACCGATTGTTGATAAACCAACTATCCAATACATTGTAGAAGAAGCAGTAAAATCAGGAATCGAAGATATTA
TTATCGTTACTGGTAAAACGAAGCGTTCTATTGAAGATCATTTTGATAATGCATTTGAGTTAGAGCAAAACTTATTAGAA
AAGAAAAAGTATGAGTTACTTGAAAAAGTACAGGCTTCTTCAAAAATGGTAGACATTCACTATATCCGTCAAAAAGAACC
AAAAGGATTAGGTCACGCTGTTTGGTGTGCACGTAAATTCATCGGTGATGAGCCATTTGCTGTTTTATTAGGTGATGATA
TCGTTCAAGCTGAAAAACCATGTTTACGTCAATTAATTGAAGAATATGATAAAACGCTTTCTTCTGTTATTGGTGTACAA
ACGGTTCCAGAAGACGAAACACACCGCTACGGAATTATTGATCCGTTAGAGCAAGAAGGACGTCGTTACCAAGTTCGCAA
TTTCGTTGAGAAACCAGCGGCAGGTACAGCACCTTCAAACTTAGCAATTATGGGACGTTACGTTTTAACACCTGAAATCT
TCATGTTCTTAGAACAACAACATGTTGGTGCTGGTGGTGAAATCCAGTTAACAGATGCTATTCAAAGCTTAAACGAAATT
CAACGTGTATTCGCTTACGATTTCGAAGGAAAGCGCTACGACGTAGGTGAAAAGCTAGGATTCGTTCAAACGACAATCGA
AATGGCACTGCAGCACCCAGAATTACGTGATGACATGGTTACGATGATGAAGAAAATTTTAGAAGAACAAACGAATCAAG
AGTCTTAA

Upstream 100 bases:

>100_bases
AATTTTAAGTAGTAGGAAACAAAAGGGAGCGAAACCTCCCTTTTGTTCTATGTAAGGAAATAATCGTTATTGATTCTGAC
AGAAGAGAGGGTATTTTGTG

Downstream 100 bases:

>100_bases
TATAAAAAAAGAGTTATCTTAACATAGTAAGATAACTCTTTTTTATTATGAAATCGTCGAATGAGAATGCTGATAAGCGG
AACGACGTACAGCATAGTAT

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKRVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAVKSGIEDIIIVTGKTKRSIEDHFDNAFELEQNLLE
KKKYELLEKVQASSKMVDIHYIRQKEPKGLGHAVWCARKFIGDEPFAVLLGDDIVQAEKPCLRQLIEEYDKTLSSVIGVQ
TVPEDETHRYGIIDPLEQEGRRYQVRNFVEKPAAGTAPSNLAIMGRYVLTPEIFMFLEQQHVGAGGEIQLTDAIQSLNEI
QRVFAYDFEGKRYDVGEKLGFVQTTIEMALQHPELRDDMVTMMKKILEEQTNQES

Sequences:

>Translated_295_residues
MKRVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAVKSGIEDIIIVTGKTKRSIEDHFDNAFELEQNLLE
KKKYELLEKVQASSKMVDIHYIRQKEPKGLGHAVWCARKFIGDEPFAVLLGDDIVQAEKPCLRQLIEEYDKTLSSVIGVQ
TVPEDETHRYGIIDPLEQEGRRYQVRNFVEKPAAGTAPSNLAIMGRYVLTPEIFMFLEQQHVGAGGEIQLTDAIQSLNEI
QRVFAYDFEGKRYDVGEKLGFVQTTIEMALQHPELRDDMVTMMKKILEEQTNQES
>Mature_295_residues
MKRVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAVKSGIEDIIIVTGKTKRSIEDHFDNAFELEQNLLE
KKKYELLEKVQASSKMVDIHYIRQKEPKGLGHAVWCARKFIGDEPFAVLLGDDIVQAEKPCLRQLIEEYDKTLSSVIGVQ
TVPEDETHRYGIIDPLEQEGRRYQVRNFVEKPAAGTAPSNLAIMGRYVLTPEIFMFLEQQHVGAGGEIQLTDAIQSLNEI
QRVFAYDFEGKRYDVGEKLGFVQTTIEMALQHPELRDDMVTMMKKILEEQTNQES

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=297, Percent_Identity=47.1380471380471, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1788355, Length=277, Percent_Identity=43.6823104693141, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1788351, Length=231, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790224, Length=269, Percent_Identity=27.5092936802974, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 33551; Mature: 33551

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAVKSGIEDIIIVTGKT
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRSIEDHFDNAFELEQNLLEKKKYELLEKVQASSKMVDIHYIRQKEPKGLGHAVWCARKF
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCHHHHHHHHHH
IGDEPFAVLLGDDIVQAEKPCLRQLIEEYDKTLSSVIGVQTVPEDETHRYGIIDPLEQEG
HCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCC
RRYQVRNFVEKPAAGTAPSNLAIMGRYVLTPEIFMFLEQQHVGAGGEIQLTDAIQSLNEI
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
QRVFAYDFEGKRYDVGEKLGFVQTTIEMALQHPELRDDMVTMMKKILEEQTNQES
HHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAVKSGIEDIIIVTGKT
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRSIEDHFDNAFELEQNLLEKKKYELLEKVQASSKMVDIHYIRQKEPKGLGHAVWCARKF
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCHHHHHHHHHH
IGDEPFAVLLGDDIVQAEKPCLRQLIEEYDKTLSSVIGVQTVPEDETHRYGIIDPLEQEG
HCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCC
RRYQVRNFVEKPAAGTAPSNLAIMGRYVLTPEIFMFLEQQHVGAGGEIQLTDAIQSLNEI
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
QRVFAYDFEGKRYDVGEKLGFVQTTIEMALQHPELRDDMVTMMKKILEEQTNQES
HHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]