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The map label for this gene is ycaK [C]

Identifier: 52140575

GI number: 52140575

Start: 4784423

End: 4785004

Strand: Direct

Name: ycaK [C]

Synonym: BCZK4683

Alternate gene names: 52140575

Gene position: 4784423-4785004 (Clockwise)

Preceding gene: 52140576

Following gene: 52140569

Centisome position: 90.26

GC content: 37.8

Gene sequence:

>582_bases
ATGAAACATGTAATCGTTTATGCACACCCAAATACAGAAAGCTTCAACCATGCGATTTTAGAAACGGTAAAAAGTGAATT
AGAAGAAAAAGGTCATGAAGTACGCGTTCGCGATCTATATGAATTAAACTTCAATCCAGTATTAGGCGCTTCCGATTTCA
TCTCATTTTCTCAAGGAAACACACCAGCAGATATTAAAGAAGAGCAAGAGCATATCTCTTGGGCTGATAGCATTACGTTT
ATTTATCCAGTTTGGTGGGCGGGACTTCCTGCTATTTTAAAAGGATACGTTGACCGTGTATTTAGCCACGGCTTCGCTTA
TGCTTACGGTGAAAATGGCATCGAGAAGTTATTAAGCGGTAAAAAAGGATTATTATTATCTACAATGGGAAATACGAAAG
AGGCATACACAGCAGGCGGTATGTTTGACGCAATGAAAAAAACAGCTGATGTTGGTATTTTTGAATTTACAGGCATTGAA
ACAATTGAGCATACATTCTATACAAGTGTCCCTTCTGTGGATGATAGTGTGCGTAAACAATATCTTGAAGAGGTTAAGGA
TGTTGTGAATCGTGCATTTTAA

Upstream 100 bases:

>100_bases
GCGTCTTTTTATACATATGTATTACTTGACTTTCGTAAAAGAAGTAACAATAATGGTTACAGAGAAACCATTCACATATC
CACAAATAGGAGGAAGAACA

Downstream 100 bases:

>100_bases
TAAAAAAACTCCGGCTTTAACAACCGGAGTTTTTCATTTCATCATCAATTTCGGAATATATCTTTGAAGAATACTTTCTA
ATTCACTCATATCTTCCTGT

Product: NAD(P)H dehydrogenase (quinone)

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKHVIVYAHPNTESFNHAILETVKSELEEKGHEVRVRDLYELNFNPVLGASDFISFSQGNTPADIKEEQEHISWADSITF
IYPVWWAGLPAILKGYVDRVFSHGFAYAYGENGIEKLLSGKKGLLLSTMGNTKEAYTAGGMFDAMKKTADVGIFEFTGIE
TIEHTFYTSVPSVDDSVRKQYLEEVKDVVNRAF

Sequences:

>Translated_193_residues
MKHVIVYAHPNTESFNHAILETVKSELEEKGHEVRVRDLYELNFNPVLGASDFISFSQGNTPADIKEEQEHISWADSITF
IYPVWWAGLPAILKGYVDRVFSHGFAYAYGENGIEKLLSGKKGLLLSTMGNTKEAYTAGGMFDAMKKTADVGIFEFTGIE
TIEHTFYTSVPSVDDSVRKQYLEEVKDVVNRAF
>Mature_193_residues
MKHVIVYAHPNTESFNHAILETVKSELEEKGHEVRVRDLYELNFNPVLGASDFISFSQGNTPADIKEEQEHISWADSITF
IYPVWWAGLPAILKGYVDRVFSHGFAYAYGENGIEKLLSGKKGLLLSTMGNTKEAYTAGGMFDAMKKTADVGIFEFTGIE
TIEHTFYTSVPSVDDSVRKQYLEEVKDVVNRAF

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=157, Percent_Identity=35.031847133758, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4505415, Length=202, Percent_Identity=31.6831683168317, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI70995396, Length=199, Percent_Identity=29.6482412060301, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787129, Length=196, Percent_Identity=27.5510204081633, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786231, Length=150, Percent_Identity=32.6666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789406, Length=147, Percent_Identity=28.5714285714286, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 21710; Mature: 21710

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVIVYAHPNTESFNHAILETVKSELEEKGHEVRVRDLYELNFNPVLGASDFISFSQGN
CCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHEECCCCCCCCHHHHHCCCCCC
TPADIKEEQEHISWADSITFIYPVWWAGLPAILKGYVDRVFSHGFAYAYGENGIEKLLSG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCC
KKGLLLSTMGNTKEAYTAGGMFDAMKKTADVGIFEFTGIETIEHTFYTSVPSVDDSVRKQ
CCCEEEEECCCCCHHHHCCCHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCCHHHHHH
YLEEVKDVVNRAF
HHHHHHHHHHHCC
>Mature Secondary Structure
MKHVIVYAHPNTESFNHAILETVKSELEEKGHEVRVRDLYELNFNPVLGASDFISFSQGN
CCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHEECCCCCCCCHHHHHCCCCCC
TPADIKEEQEHISWADSITFIYPVWWAGLPAILKGYVDRVFSHGFAYAYGENGIEKLLSG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCC
KKGLLLSTMGNTKEAYTAGGMFDAMKKTADVGIFEFTGIETIEHTFYTSVPSVDDSVRKQ
CCCEEEEECCCCCHHHHCCCHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCCHHHHHH
YLEEVKDVVNRAF
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]