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The map label for this gene is resE [H]

Identifier: 52140508

GI number: 52140508

Start: 4843324

End: 4844775

Strand: Reverse

Name: resE [H]

Synonym: BCZK4751

Alternate gene names: 52140508

Gene position: 4844775-4843324 (Counterclockwise)

Preceding gene: 52140505

Following gene: 52140509

Centisome position: 91.4

GC content: 36.16

Gene sequence:

>1452_bases
GTGGAGTGTACAAAATTGATGCAAAGGTTACGGATTAAACAACAGCTAGTAATTGGCTTCTTAATAGTTTTAATTGGTAG
TTTAATACTGACGGTTTTAACGGCGGCTAGTGGTTGGTATTGGCTAACGAAGAGTGGAAAAGTATTTCCTGCAAATTATT
ATGAGCAGAAAATTCCTATGATAAAAGAATACGTAAAAGATAAAGGCGCGCTATTGTTAGACGAGAAAGAGCGATATGAA
TTAGAGAAAGTTGTCCCTAGTGAGGGCATTCAATATCAAATTGTTAATAGGCAAGGAGGTATTTCTTATGGTACATATAA
AAAGAAAGTAATAACAAATGAGAGACCAATTTTGAGTGTTATTAATACAAATATTCATGAGGAAGATGATGATAATGAAG
TTACGACATATCTGCCTTTAGTGGATAAGAATGGAGATTTACAAGGAGCGATAGGGTTTAATTATCATTTGATAATATCA
ACCGCTTCGGCAGTTGATTCCTTTTTTGTAATCTTATTTTTAGCTTCACCCTTTATATACATTACAATTTTATCCTACAT
CGTTTCAAACCGAATGGGAAAAAGAATAAAGAAACCACTCGCTGAATTATCAGAGGCTTCAAAAAGAATTCAAGAGCAGG
ATTTAAATTTTCATTTAGAATACAACGCGCAAAATGAGATTGGTGAATTAGTCAGTTCGTTTGAAAATATGCGCGGAGCA
TTAGCTACTAGTTTGTCACGACAATGGGAGTTAGAAGAAGAAAGAAGAGAATACATTAGAGCTATTTCCCATGATTTGAA
AACACCGCTAACGATTGTGCAAGGTCATGCAGAAGGTCTGCAAAGTGGCTTATGGAAAAATGAAGATTTGTTACATCGTT
ATTTACAAACGATTGAACGAAACACAAACAGAATGACAAAACTTCTTGAGGAGTTCCAAACAGTAAATGAGTTAGAAAGC
TTCGCATTTCAATTACGTTTAAATAGAGTGCATATAAATCCATTCTTTCTAAAAAAGCTAGAAGAATATGAATGTATAGC
TAGGAAAAAAGAAATTGAGTGGGATGTTATCTTTGAAAACAATGAGGATGTACAAAGCTTAGTATTTGACCAAGAGCGGA
TCAGTCAAGTAATGGATAATATCGTAATGAATGCAGTTCGGTTTACCACGGTGTCAGGGAAGGTGCTCGTTAAAGTGTGT
ACTTGGCATGACACAATAGAGTTTCATGTATATGATTCAGGGCCTGGTTTCCAAGAAGGAGATTTGAAAAAAGTATTACA
ACGTTTTTATCAAGGAGATCAGTCACGCTCAGGAAGCAAGGAGCATTTTGGACTCGGTTTATATATTGCTAAGACAATTG
TTGAGAAGCACGGCGGTAAAATACAGGTAGAAAATAGCGAGGTGCGAGGTGGGGCGCATGTTTCGTTTCGGATTCCGAGC
GGGGGAATGTAG

Upstream 100 bases:

>100_bases
TTTCTACTGTAGTTGAGCATATAAAGAAAATTAGAACAAAGCTTAGTGTATATGATAGAGAATATACATATATTCAAACG
GTGTGGGGAATTGGATATAA

Downstream 100 bases:

>100_bases
GAAAGAAGTTGCCGTGAAGGTAACTTCTTTTTATTGTGGTGACGGGATCTGCAAAACAACATAAAAAAAGCTGGAAGAAT
CCTTCCAGCTTACGAGTTAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MECTKLMQRLRIKQQLVIGFLIVLIGSLILTVLTAASGWYWLTKSGKVFPANYYEQKIPMIKEYVKDKGALLLDEKERYE
LEKVVPSEGIQYQIVNRQGGISYGTYKKKVITNERPILSVINTNIHEEDDDNEVTTYLPLVDKNGDLQGAIGFNYHLIIS
TASAVDSFFVILFLASPFIYITILSYIVSNRMGKRIKKPLAELSEASKRIQEQDLNFHLEYNAQNEIGELVSSFENMRGA
LATSLSRQWELEEERREYIRAISHDLKTPLTIVQGHAEGLQSGLWKNEDLLHRYLQTIERNTNRMTKLLEEFQTVNELES
FAFQLRLNRVHINPFFLKKLEEYECIARKKEIEWDVIFENNEDVQSLVFDQERISQVMDNIVMNAVRFTTVSGKVLVKVC
TWHDTIEFHVYDSGPGFQEGDLKKVLQRFYQGDQSRSGSKEHFGLGLYIAKTIVEKHGGKIQVENSEVRGGAHVSFRIPS
GGM

Sequences:

>Translated_483_residues
MECTKLMQRLRIKQQLVIGFLIVLIGSLILTVLTAASGWYWLTKSGKVFPANYYEQKIPMIKEYVKDKGALLLDEKERYE
LEKVVPSEGIQYQIVNRQGGISYGTYKKKVITNERPILSVINTNIHEEDDDNEVTTYLPLVDKNGDLQGAIGFNYHLIIS
TASAVDSFFVILFLASPFIYITILSYIVSNRMGKRIKKPLAELSEASKRIQEQDLNFHLEYNAQNEIGELVSSFENMRGA
LATSLSRQWELEEERREYIRAISHDLKTPLTIVQGHAEGLQSGLWKNEDLLHRYLQTIERNTNRMTKLLEEFQTVNELES
FAFQLRLNRVHINPFFLKKLEEYECIARKKEIEWDVIFENNEDVQSLVFDQERISQVMDNIVMNAVRFTTVSGKVLVKVC
TWHDTIEFHVYDSGPGFQEGDLKKVLQRFYQGDQSRSGSKEHFGLGLYIAKTIVEKHGGKIQVENSEVRGGAHVSFRIPS
GGM
>Mature_483_residues
MECTKLMQRLRIKQQLVIGFLIVLIGSLILTVLTAASGWYWLTKSGKVFPANYYEQKIPMIKEYVKDKGALLLDEKERYE
LEKVVPSEGIQYQIVNRQGGISYGTYKKKVITNERPILSVINTNIHEEDDDNEVTTYLPLVDKNGDLQGAIGFNYHLIIS
TASAVDSFFVILFLASPFIYITILSYIVSNRMGKRIKKPLAELSEASKRIQEQDLNFHLEYNAQNEIGELVSSFENMRGA
LATSLSRQWELEEERREYIRAISHDLKTPLTIVQGHAEGLQSGLWKNEDLLHRYLQTIERNTNRMTKLLEEFQTVNELES
FAFQLRLNRVHINPFFLKKLEEYECIARKKEIEWDVIFENNEDVQSLVFDQERISQVMDNIVMNAVRFTTVSGKVLVKVC
TWHDTIEFHVYDSGPGFQEGDLKKVLQRFYQGDQSRSGSKEHFGLGLYIAKTIVEKHGGKIQVENSEVRGGAHVSFRIPS
GGM

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=282, Percent_Identity=24.468085106383, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=29.3877551020408, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=24.7826086956522, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=393, Percent_Identity=24.4274809160305, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=282, Percent_Identity=23.0496453900709, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=27.1698113207547, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=347, Percent_Identity=23.342939481268, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=255, Percent_Identity=24.7058823529412, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790436, Length=209, Percent_Identity=23.9234449760766, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=26.7241379310345, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=23.3766233766234, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=24.6212121212121, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=25.1063829787234, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=301, Percent_Identity=24.2524916943522, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=209, Percent_Identity=22.488038277512, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55564; Mature: 55564

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECTKLMQRLRIKQQLVIGFLIVLIGSLILTVLTAASGWYWLTKSGKVFPANYYEQKIPM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHCHH
IKEYVKDKGALLLDEKERYELEKVVPSEGIQYQIVNRQGGISYGTYKKKVITNERPILSV
HHHHHHCCCCEEECCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCHHH
INTNIHEEDDDNEVTTYLPLVDKNGDLQGAIGFNYHLIISTASAVDSFFVILFLASPFIY
HCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
ITILSYIVSNRMGKRIKKPLAELSEASKRIQEQDLNFHLEYNAQNEIGELVSSFENMRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
LATSLSRQWELEEERREYIRAISHDLKTPLTIVQGHAEGLQSGLWKNEDLLHRYLQTIER
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHCCCCCHHHHHHHHHHHHH
NTNRMTKLLEEFQTVNELESFAFQLRLNRVHINPFFLKKLEEYECIARKKEIEWDVIFEN
CHHHHHHHHHHHHHHHHHHHHHHHHEECEEECCHHHHHHHHHHHHHHHHHCCCEEEEECC
NEDVQSLVFDQERISQVMDNIVMNAVRFTTVSGKVLVKVCTWHDTIEFHVYDSGPGFQEG
CCHHHHHHHCHHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCEEEEEEEECCCCCCCC
DLKKVLQRFYQGDQSRSGSKEHFGLGLYIAKTIVEKHGGKIQVENSEVRGGAHVSFRIPS
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCC
GGM
CCC
>Mature Secondary Structure
MECTKLMQRLRIKQQLVIGFLIVLIGSLILTVLTAASGWYWLTKSGKVFPANYYEQKIPM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHCHH
IKEYVKDKGALLLDEKERYELEKVVPSEGIQYQIVNRQGGISYGTYKKKVITNERPILSV
HHHHHHCCCCEEECCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCHHH
INTNIHEEDDDNEVTTYLPLVDKNGDLQGAIGFNYHLIISTASAVDSFFVILFLASPFIY
HCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
ITILSYIVSNRMGKRIKKPLAELSEASKRIQEQDLNFHLEYNAQNEIGELVSSFENMRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
LATSLSRQWELEEERREYIRAISHDLKTPLTIVQGHAEGLQSGLWKNEDLLHRYLQTIER
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHCCCCCHHHHHHHHHHHHH
NTNRMTKLLEEFQTVNELESFAFQLRLNRVHINPFFLKKLEEYECIARKKEIEWDVIFEN
CHHHHHHHHHHHHHHHHHHHHHHHHEECEEECCHHHHHHHHHHHHHHHHHCCCEEEEECC
NEDVQSLVFDQERISQVMDNIVMNAVRFTTVSGKVLVKVCTWHDTIEFHVYDSGPGFQEG
CCHHHHHHHCHHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCEEEEEEEECCCCCCCC
DLKKVLQRFYQGDQSRSGSKEHFGLGLYIAKTIVEKHGGKIQVENSEVRGGAHVSFRIPS
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCC
GGM
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]