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The map label for this gene is rpoB

Identifier: 51894220

GI number: 51894220

Start: 3285098

End: 3288850

Strand: Reverse

Name: rpoB

Synonym: STH3085

Alternate gene names: 51894220

Gene position: 3288850-3285098 (Counterclockwise)

Preceding gene: 51894221

Following gene: 51894219

Centisome position: 92.22

GC content: 67.09

Gene sequence:

>3753_bases
ATGCCGAAGATCGTGCAAGCTGGCAGGAGACAGCGGCTGAGCTTCTCCCGGATCGATGAGGTTCTGGAGATGCCGAACCT
GATCGAGCTTCAGCGCAACTCCTATCAGTGGTTCCTGCGTGAGGGCCTGCAGGAGATGTTCCAGGACATCTCGCCCATTC
AGGACTTCACCGGCAACCTGGTGCTGGAGTTCATCGACTACAGCTTGGGCGAACCGAAGTACTCGATCGAGGAGTGCAAG
GAGCGGGATGTCACGTATGCCGCTCCGCTGCGTGTCCGGGTCCGGCTCATCAACAAGGAGACCGGCGAGGTGAAGGAGCA
GGAGGTGTTCATGGGCGACTTCCCGCTCATGACCCCCACCGGCACCTTCATCATCAACGGCGCGGAACGGGTCATCGTCT
CCCAGCTCGTCCGCTCGCCCGGGGTCTACTTCTCCGAGCAGATCGACCCCTCCGGCAAGAAGCTGTTCTTCGCGACCATG
ATCCCCAACCGGGGCGCATGGCTGGAGTTTGAGTCCGACGTCAACGACGTCATCTACGTGCGCGTCGACCGGACCCGCAA
GCTGCCCGCGACCGTCCTGCTGCGCGCCCTCGGCTTCGGCTCCGACCAGGAGATCCTCGACGCCGTGGGCGATTCGGAGT
ACATCCGCCGCACGCTGGAGAAGGACAGCACGGAGTCCGAGGAGGAGGCGCTCATCGAGATCTACAAGCGGCTGCGGCCC
GGTGAGCCGCCGGCTGCGGACAACGCGCGCCAGCTCCTGGAGACGCTGTTCTTCGAGCCGAAGCGGTACGACCTGATGCA
CGTGGGCCGCTACCGGCTGAACAAGAAGCTGGCCCTGAAGCGGCGCATCGTGGGCACGTCCACCGTCGACCGGGTGGTGC
ACCCGGAGACGGGGGAGGTGCTGGCCGAGGCCGGCGTGCAGATCGATAAGCGGCTGGCCGAGAAGATCGACGAGGCCGGC
GTGGACGCGCTGACCGTGCGGCTGCGCGACGGCGGGATCGTGCGCGTGGTCGCCAACGGCAGGCCGGACATCAGGGTGAA
GACCATCGTCCGGCAGGACATCGTCGCCGTCATCAACTACATGGTCAGTCTATTCAAGGGCCTGGGCAGCGTCGACGACA
TCGACCACCTGGGCAACCGGCGCGTGCGCTCCGTCGGCGAGCTGCTGCAGAACCAGTTCCGCATCGGCCTCGCCCGGATG
GAGCGCGTCATCAAGGAGCGCATGACCATCCAGGATGTGGACATCATCACGCCCCAGGCGTTGATCAACATCCGGCCGGT
GGTCGCCGCGGTGAAGGAGTTCTTCGGCTCCTCGCAGCTCAGCCAGTTCATGGACCAGACCAACCCCCTGGCCGAGCTGA
CCAACAAGCGGCGCCTCTCGGCCCTGGGCCCCGGCGGCCTCTCCCGGGAGCGGGCCGGGTACGAGGTGCGCGACGTGCAC
ACCTCCCACTACGGCCGCATGTGCCCCATCGAGACGCCGGAAGGTCCCAACATCGGCCTGATCGGCGCCCTGGCCACCTT
CGCCCGTATCAACGAGTACGGCTTCATCGAGACGCCGTACCGCAAGGTCGACCAGGAGAGCGGCCGGGTCACCGATGAGA
TCGTCTACCTCACCGCGGATGAGGAGGACGAGAACATCATCGCCCAGGCCAACGAGCCGCTCAATCCGGACGGCACCTTC
GCCCGGGACCGGGTCACCTGCCGCTACCGGGACGAGATCCTGCAGGTGCCGCCCAGCCAGGTGGACTACATGGACGTCTC
GCCCAAGCAGGTGGTGTCCATCGCCACGGCGCTCATCCCGTTCCTGGAGAACGACGACGCGTCGCGGGCACTGATGGGCT
CCAACATGCAGCGGCAGGCCGTGCCGCTCCTGCGCACCGAGGCCCCGTACGTGGGCACCGGCATGGAGTATCGCTCCGCC
TGGGACTCGGGCGTCTGCGTCATCGCCGAGAACGACGGCGTCGTGCTGCGGGCGACGGCCTCCGAGGTCGTCGTGCAGTA
CGACGACATGCAGGTGAAGAAGTACAAGCTGACCAAGTTCACCCGGTCCAACCAGGGCACCTGCATGAACCAGAAGCCGA
TCGTGCGCGCCGGCGACCGGGTGCGCAAGGGCGACGTGATCGCGGACGGGCCGTCCACCGACCAGGGTGAACTGGCCCTC
GGCCGCAACGTGCTGGTCGCCTACATGTGCTACGAGGGCTACAACTACGAGGACGCCATCATCATCAACGAGCGGCTCGT
GCGCGAGGACGTCTTCACCTCGATCCACATCGAGGAGCACGAGTGCGAGGCGCGCGACACCAAGCTGGGGCCCGAGGAGA
TCACCCGGGACATCCCCAACGTCGGCGAGGACGTGCTGAAGGACCTGGACGAGCGCGGCATCATCCGCATCGGCGCCGAG
GTGCGGCCGGGCGACATCCTGGTCGGCAAGGTCACGCCCAAGGGCGAGACCGAGCTCACGGCTGAGGAGCGGCTGCTGCG
GGCGATCTTCGGCGAGAAGGCGCGGGAGGTCCGCGACACGTCGCTGCGGGTGCCGCACGGCGAGTCGGGCATCGTCGTGG
ACGTCAAGGTCTTCACCCGTGAGAACGGCGACGAGCTCTCGCCCGGCGTGAACGAGCTGGTGCGGGTCTACATGGCCCAG
AAGCGCAAGATCAGCCAGGGCGACAAGATGGCCGGCCGCCACGGCAACAAGGGCGTCATCTCCGTCATCGTCCCGGAGGA
AGACATGCCCTTCATGCCCGACGGCACGCCGATCGACATCATCCTGACGCCGCTGGGCGTGCCCTCCCGCATGAACATCG
GCCAGATCATGGAGATCCACCTGGGCTGGGCGGCCAAGACCCTGGGCATGTACGTGGCCAGCCCGGTCTTCGACGGCGCC
AACGAGCAGGACATCCGGGAGATGCTGCTGAAGGCCCACCTGCCGCCCAACGGCAAGACGGTGCTCTACGACGGCAAGAC
CGGCGAGCCCTTCGACAACGAGGTCACCGTCGGCTACAAGTACATGCTGAAACTCCACCACCTGGTGGACGACAAGATCC
ACGCCCGGTCCACGGGCCCGTACTCGCTGGTCACCCAGCAGCCCCTGGGCGGCAAGGCGCAGTTCGGCGGCCAGCGCTTC
GGCGAGATGGAGGTGTGGGCGCTGGAGGCCTACGGCGCCGCCTACACGCTGCAGGAGCTGCTCACGGTCAAGTCCGACGA
CGTGGTCGGCCGCGTGAAGACCTACGAGGCCATCGTGAAGGGCGAGAACGTGCCGGAGCCCGGCGTGCCCGAGTCGTTCA
AGGTGCTCATCAAGGAGCTGCAGTCCCTGGCCCTGGACGTCAAGGTGCTCGACGAGAGCGGCAACGAGATCGAGCTGCGC
GAGCTGGACGACGAGATGGACCTGTCCGACCGCGACCTGGAGATCCCGACGCTGGGCGGCGCGGAGCTGGCGAAGCCTGC
GCCCGACGCCCAGGCCGGCGAGGAATCGGGCGAGGCCGGGGAGGAGTCCGAGGGCGAGCCCGAAGAGGAGGACGTGGAGG
AGATCGACGTTCCCCTCGATCCGGAGGAGCTGGAGAAGGTCGCGGGCGCCCTGAAGAACCCCGTGCGCGCGGGCCGCCGC
GGCGCCGGTGGCGGGCTGGCCGACGACGACCAGGAGATGGACGAGGAGGACCTGTTCGACGAGGGCGACGAGGATCTGGC
GGACGACGTCGGTCTCTACCGGGGCCGCAGCCGCCGCCTGGCGGACGACTTCGGCGACGAAGAGGAAGAGTAG

Upstream 100 bases:

>100_bases
GCGGGGGAGTTGATGATACATCGAGCGCTTCCGCGGTGGGCACTTCCAGACGGGGAGCTTCTTGATGGCCACCATACAGG
AGCGAGGAGGCCTAGACCGC

Downstream 100 bases:

>100_bases
GGGAGGGTGCTGAGCGATGCTCGATGTCAATTTCTTTGACTCCATCCAAATCGGCCTGGCCTCTCCCGAACGCATCCGGC
AGTGGTCCCGCGGCGAGGTA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1250; Mature: 1249

Protein sequence:

>1250_residues
MPKIVQAGRRQRLSFSRIDEVLEMPNLIELQRNSYQWFLREGLQEMFQDISPIQDFTGNLVLEFIDYSLGEPKYSIEECK
ERDVTYAAPLRVRVRLINKETGEVKEQEVFMGDFPLMTPTGTFIINGAERVIVSQLVRSPGVYFSEQIDPSGKKLFFATM
IPNRGAWLEFESDVNDVIYVRVDRTRKLPATVLLRALGFGSDQEILDAVGDSEYIRRTLEKDSTESEEEALIEIYKRLRP
GEPPAADNARQLLETLFFEPKRYDLMHVGRYRLNKKLALKRRIVGTSTVDRVVHPETGEVLAEAGVQIDKRLAEKIDEAG
VDALTVRLRDGGIVRVVANGRPDIRVKTIVRQDIVAVINYMVSLFKGLGSVDDIDHLGNRRVRSVGELLQNQFRIGLARM
ERVIKERMTIQDVDIITPQALINIRPVVAAVKEFFGSSQLSQFMDQTNPLAELTNKRRLSALGPGGLSRERAGYEVRDVH
TSHYGRMCPIETPEGPNIGLIGALATFARINEYGFIETPYRKVDQESGRVTDEIVYLTADEEDENIIAQANEPLNPDGTF
ARDRVTCRYRDEILQVPPSQVDYMDVSPKQVVSIATALIPFLENDDASRALMGSNMQRQAVPLLRTEAPYVGTGMEYRSA
WDSGVCVIAENDGVVLRATASEVVVQYDDMQVKKYKLTKFTRSNQGTCMNQKPIVRAGDRVRKGDVIADGPSTDQGELAL
GRNVLVAYMCYEGYNYEDAIIINERLVREDVFTSIHIEEHECEARDTKLGPEEITRDIPNVGEDVLKDLDERGIIRIGAE
VRPGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGESGIVVDVKVFTRENGDELSPGVNELVRVYMAQ
KRKISQGDKMAGRHGNKGVISVIVPEEDMPFMPDGTPIDIILTPLGVPSRMNIGQIMEIHLGWAAKTLGMYVASPVFDGA
NEQDIREMLLKAHLPPNGKTVLYDGKTGEPFDNEVTVGYKYMLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRF
GEMEVWALEAYGAAYTLQELLTVKSDDVVGRVKTYEAIVKGENVPEPGVPESFKVLIKELQSLALDVKVLDESGNEIELR
ELDDEMDLSDRDLEIPTLGGAELAKPAPDAQAGEESGEAGEESEGEPEEEDVEEIDVPLDPEELEKVAGALKNPVRAGRR
GAGGGLADDDQEMDEEDLFDEGDEDLADDVGLYRGRSRRLADDFGDEEEE

Sequences:

>Translated_1250_residues
MPKIVQAGRRQRLSFSRIDEVLEMPNLIELQRNSYQWFLREGLQEMFQDISPIQDFTGNLVLEFIDYSLGEPKYSIEECK
ERDVTYAAPLRVRVRLINKETGEVKEQEVFMGDFPLMTPTGTFIINGAERVIVSQLVRSPGVYFSEQIDPSGKKLFFATM
IPNRGAWLEFESDVNDVIYVRVDRTRKLPATVLLRALGFGSDQEILDAVGDSEYIRRTLEKDSTESEEEALIEIYKRLRP
GEPPAADNARQLLETLFFEPKRYDLMHVGRYRLNKKLALKRRIVGTSTVDRVVHPETGEVLAEAGVQIDKRLAEKIDEAG
VDALTVRLRDGGIVRVVANGRPDIRVKTIVRQDIVAVINYMVSLFKGLGSVDDIDHLGNRRVRSVGELLQNQFRIGLARM
ERVIKERMTIQDVDIITPQALINIRPVVAAVKEFFGSSQLSQFMDQTNPLAELTNKRRLSALGPGGLSRERAGYEVRDVH
TSHYGRMCPIETPEGPNIGLIGALATFARINEYGFIETPYRKVDQESGRVTDEIVYLTADEEDENIIAQANEPLNPDGTF
ARDRVTCRYRDEILQVPPSQVDYMDVSPKQVVSIATALIPFLENDDASRALMGSNMQRQAVPLLRTEAPYVGTGMEYRSA
WDSGVCVIAENDGVVLRATASEVVVQYDDMQVKKYKLTKFTRSNQGTCMNQKPIVRAGDRVRKGDVIADGPSTDQGELAL
GRNVLVAYMCYEGYNYEDAIIINERLVREDVFTSIHIEEHECEARDTKLGPEEITRDIPNVGEDVLKDLDERGIIRIGAE
VRPGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGESGIVVDVKVFTRENGDELSPGVNELVRVYMAQ
KRKISQGDKMAGRHGNKGVISVIVPEEDMPFMPDGTPIDIILTPLGVPSRMNIGQIMEIHLGWAAKTLGMYVASPVFDGA
NEQDIREMLLKAHLPPNGKTVLYDGKTGEPFDNEVTVGYKYMLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRF
GEMEVWALEAYGAAYTLQELLTVKSDDVVGRVKTYEAIVKGENVPEPGVPESFKVLIKELQSLALDVKVLDESGNEIELR
ELDDEMDLSDRDLEIPTLGGAELAKPAPDAQAGEESGEAGEESEGEPEEEDVEEIDVPLDPEELEKVAGALKNPVRAGRR
GAGGGLADDDQEMDEEDLFDEGDEDLADDVGLYRGRSRRLADDFGDEEEE
>Mature_1249_residues
PKIVQAGRRQRLSFSRIDEVLEMPNLIELQRNSYQWFLREGLQEMFQDISPIQDFTGNLVLEFIDYSLGEPKYSIEECKE
RDVTYAAPLRVRVRLINKETGEVKEQEVFMGDFPLMTPTGTFIINGAERVIVSQLVRSPGVYFSEQIDPSGKKLFFATMI
PNRGAWLEFESDVNDVIYVRVDRTRKLPATVLLRALGFGSDQEILDAVGDSEYIRRTLEKDSTESEEEALIEIYKRLRPG
EPPAADNARQLLETLFFEPKRYDLMHVGRYRLNKKLALKRRIVGTSTVDRVVHPETGEVLAEAGVQIDKRLAEKIDEAGV
DALTVRLRDGGIVRVVANGRPDIRVKTIVRQDIVAVINYMVSLFKGLGSVDDIDHLGNRRVRSVGELLQNQFRIGLARME
RVIKERMTIQDVDIITPQALINIRPVVAAVKEFFGSSQLSQFMDQTNPLAELTNKRRLSALGPGGLSRERAGYEVRDVHT
SHYGRMCPIETPEGPNIGLIGALATFARINEYGFIETPYRKVDQESGRVTDEIVYLTADEEDENIIAQANEPLNPDGTFA
RDRVTCRYRDEILQVPPSQVDYMDVSPKQVVSIATALIPFLENDDASRALMGSNMQRQAVPLLRTEAPYVGTGMEYRSAW
DSGVCVIAENDGVVLRATASEVVVQYDDMQVKKYKLTKFTRSNQGTCMNQKPIVRAGDRVRKGDVIADGPSTDQGELALG
RNVLVAYMCYEGYNYEDAIIINERLVREDVFTSIHIEEHECEARDTKLGPEEITRDIPNVGEDVLKDLDERGIIRIGAEV
RPGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGESGIVVDVKVFTRENGDELSPGVNELVRVYMAQK
RKISQGDKMAGRHGNKGVISVIVPEEDMPFMPDGTPIDIILTPLGVPSRMNIGQIMEIHLGWAAKTLGMYVASPVFDGAN
EQDIREMLLKAHLPPNGKTVLYDGKTGEPFDNEVTVGYKYMLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFG
EMEVWALEAYGAAYTLQELLTVKSDDVVGRVKTYEAIVKGENVPEPGVPESFKVLIKELQSLALDVKVLDESGNEIELRE
LDDEMDLSDRDLEIPTLGGAELAKPAPDAQAGEESGEAGEESEGEPEEEDVEEIDVPLDPEELEKVAGALKNPVRAGRRG
AGGGLADDDQEMDEEDLFDEGDEDLADDVGLYRGRSRRLADDFGDEEEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI4505941, Length=418, Percent_Identity=32.2966507177034, Blast_Score=183, Evalue=9e-46,
Organism=Homo sapiens, GI238908505, Length=408, Percent_Identity=31.6176470588235, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI238908503, Length=408, Percent_Identity=31.6176470588235, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI212286172, Length=427, Percent_Identity=29.5081967213115, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI33469941, Length=427, Percent_Identity=29.5081967213115, Blast_Score=155, Evalue=2e-37,
Organism=Escherichia coli, GI1790419, Length=952, Percent_Identity=48.4243697478992, Blast_Score=842, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=418, Percent_Identity=32.5358851674641, Blast_Score=187, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI25144348, Length=437, Percent_Identity=30.8924485125858, Blast_Score=182, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17506623, Length=184, Percent_Identity=41.8478260869565, Blast_Score=130, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324725, Length=413, Percent_Identity=31.9612590799031, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6324781, Length=425, Percent_Identity=28.7058823529412, Blast_Score=171, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6325267, Length=360, Percent_Identity=33.6111111111111, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17136444, Length=419, Percent_Identity=30.5489260143198, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17647877, Length=420, Percent_Identity=30.7142857142857, Blast_Score=171, Evalue=4e-42,
Organism=Drosophila melanogaster, GI17136446, Length=425, Percent_Identity=30.1176470588235, Blast_Score=124, Evalue=5e-28,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_SYMTH (Q67JT3)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076911.1
- ProteinModelPortal:   Q67JT3
- SMR:   Q67JT3
- GeneID:   2979369
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH3085
- NMPDR:   fig|292459.1.peg.2956
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- BioCyc:   STHE292459:STH3085-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 139534; Mature: 139403

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIVQAGRRQRLSFSRIDEVLEMPNLIELQRNSYQWFLREGLQEMFQDISPIQDFTGNL
CCCHHHHHHHHCCCHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
VLEFIDYSLGEPKYSIEECKERDVTYAAPLRVRVRLINKETGEVKEQEVFMGDFPLMTPT
HHHHHHHHCCCCCCCHHHHHHCCCEEECCEEEEEEEECCCCCCCCHHHEEECCCCCCCCC
GTFIINGAERVIVSQLVRSPGVYFSEQIDPSGKKLFFATMIPNRGAWLEFESDVNDVIYV
CCEEECCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCEEEEE
RVDRTRKLPATVLLRALGFGSDQEILDAVGDSEYIRRTLEKDSTESEEEALIEIYKRLRP
EECCCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
GEPPAADNARQLLETLFFEPKRYDLMHVGRYRLNKKLALKRRIVGTSTVDRVVHPETGEV
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
LAEAGVQIDKRLAEKIDEAGVDALTVRLRDGGIVRVVANGRPDIRVKTIVRQDIVAVINY
HHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
MVSLFKGLGSVDDIDHLGNRRVRSVGELLQNQFRIGLARMERVIKERMTIQDVDIITPQA
HHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHH
LINIRPVVAAVKEFFGSSQLSQFMDQTNPLAELTNKRRLSALGPGGLSRERAGYEVRDVH
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCEECC
TSHYGRMCPIETPEGPNIGLIGALATFARINEYGFIETPYRKVDQESGRVTDEIVYLTAD
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEEEEEEC
EEDENIIAQANEPLNPDGTFARDRVTCRYRDEILQVPPSQVDYMDVSPKQVVSIATALIP
CCCCCEEEECCCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
FLENDDASRALMGSNMQRQAVPLLRTEAPYVGTGMEYRSAWDSGVCVIAENDGVVLRATA
HHCCCCHHHHHHCCCCHHHCCCHHCCCCCCCCCCCHHHHCCCCCEEEEECCCCEEEEEEC
SEVVVQYDDMQVKKYKLTKFTRSNQGTCMNQKPIVRAGDRVRKGDVIADGPSTDQGELAL
CCEEEEECCCEEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEC
GRNVLVAYMCYEGYNYEDAIIINERLVREDVFTSIHIEEHECEARDTKLGPEEITRDIPN
CCCEEEEEEEECCCCCCCEEEECHHHHHHHHHHEEEEEHHHCCCCCCCCCHHHHHHHCCC
VGEDVLKDLDERGIIRIGAEVRPGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDT
CHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
SLRVPHGESGIVVDVKVFTRENGDELSPGVNELVRVYMAQKRKISQGDKMAGRHGNKGVI
CEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEE
SVIVPEEDMPFMPDGTPIDIILTPLGVPSRMNIGQIMEIHLGWAAKTLGMYVASPVFDGA
EEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCC
NEQDIREMLLKAHLPPNGKTVLYDGKTGEPFDNEVTVGYKYMLKLHHLVDDKIHARSTGP
CHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCHHHCCCCCC
YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQELLTVKSDDVVGRVKTYEAIVK
EEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GENVPEPGVPESFKVLIKELQSLALDVKVLDESGNEIELRELDDEMDLSDRDLEIPTLGG
CCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCC
AELAKPAPDAQAGEESGEAGEESEGEPEEEDVEEIDVPLDPEELEKVAGALKNPVRAGRR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
GAGGGLADDDQEMDEEDLFDEGDEDLADDVGLYRGRSRRLADDFGDEEEE
CCCCCCCCCHHHCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
PKIVQAGRRQRLSFSRIDEVLEMPNLIELQRNSYQWFLREGLQEMFQDISPIQDFTGNL
CCHHHHHHHHCCCHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
VLEFIDYSLGEPKYSIEECKERDVTYAAPLRVRVRLINKETGEVKEQEVFMGDFPLMTPT
HHHHHHHHCCCCCCCHHHHHHCCCEEECCEEEEEEEECCCCCCCCHHHEEECCCCCCCCC
GTFIINGAERVIVSQLVRSPGVYFSEQIDPSGKKLFFATMIPNRGAWLEFESDVNDVIYV
CCEEECCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCEEEEE
RVDRTRKLPATVLLRALGFGSDQEILDAVGDSEYIRRTLEKDSTESEEEALIEIYKRLRP
EECCCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
GEPPAADNARQLLETLFFEPKRYDLMHVGRYRLNKKLALKRRIVGTSTVDRVVHPETGEV
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
LAEAGVQIDKRLAEKIDEAGVDALTVRLRDGGIVRVVANGRPDIRVKTIVRQDIVAVINY
HHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
MVSLFKGLGSVDDIDHLGNRRVRSVGELLQNQFRIGLARMERVIKERMTIQDVDIITPQA
HHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHH
LINIRPVVAAVKEFFGSSQLSQFMDQTNPLAELTNKRRLSALGPGGLSRERAGYEVRDVH
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCEECC
TSHYGRMCPIETPEGPNIGLIGALATFARINEYGFIETPYRKVDQESGRVTDEIVYLTAD
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEEEEEEC
EEDENIIAQANEPLNPDGTFARDRVTCRYRDEILQVPPSQVDYMDVSPKQVVSIATALIP
CCCCCEEEECCCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
FLENDDASRALMGSNMQRQAVPLLRTEAPYVGTGMEYRSAWDSGVCVIAENDGVVLRATA
HHCCCCHHHHHHCCCCHHHCCCHHCCCCCCCCCCCHHHHCCCCCEEEEECCCCEEEEEEC
SEVVVQYDDMQVKKYKLTKFTRSNQGTCMNQKPIVRAGDRVRKGDVIADGPSTDQGELAL
CCEEEEECCCEEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEC
GRNVLVAYMCYEGYNYEDAIIINERLVREDVFTSIHIEEHECEARDTKLGPEEITRDIPN
CCCEEEEEEEECCCCCCCEEEECHHHHHHHHHHEEEEEHHHCCCCCCCCCHHHHHHHCCC
VGEDVLKDLDERGIIRIGAEVRPGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDT
CHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
SLRVPHGESGIVVDVKVFTRENGDELSPGVNELVRVYMAQKRKISQGDKMAGRHGNKGVI
CEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEE
SVIVPEEDMPFMPDGTPIDIILTPLGVPSRMNIGQIMEIHLGWAAKTLGMYVASPVFDGA
EEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCC
NEQDIREMLLKAHLPPNGKTVLYDGKTGEPFDNEVTVGYKYMLKLHHLVDDKIHARSTGP
CHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCHHHCCCCCC
YSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQELLTVKSDDVVGRVKTYEAIVK
EEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GENVPEPGVPESFKVLIKELQSLALDVKVLDESGNEIELRELDDEMDLSDRDLEIPTLGG
CCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCC
AELAKPAPDAQAGEESGEAGEESEGEPEEEDVEEIDVPLDPEELEKVAGALKNPVRAGRR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
GAGGGLADDDQEMDEEDLFDEGDEDLADDVGLYRGRSRRLADDFGDEEEE
CCCCCCCCCHHHCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA