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The map label for this gene is flhF [H]

Identifier: 51894122

GI number: 51894122

Start: 3206873

End: 3208309

Strand: Reverse

Name: flhF [H]

Synonym: STH2986

Alternate gene names: 51894122

Gene position: 3208309-3206873 (Counterclockwise)

Preceding gene: 51894123

Following gene: 51894121

Centisome position: 89.97

GC content: 72.3

Gene sequence:

>1437_bases
GTGAAGAAGTACATGGCCCCCACGTACGCGGAGGCCCTGATTCTGGCAAAGAACGAACTCGGCACCGACGCCGTCATCGT
CGACAGCCGCAAGGTGCGGGTGGGCGGCATTTTCGGCCTCTTCGGCCGCGTGATGACCGAACTCACCGTCGCGGCCGATC
AGCGGCCGCAGCCTTACCGGGGCGCGCGCCCGGCGGCACGCCCGCGCGGCGCAACCGCACCGTCCGGGGCGCCGGCTTCC
GCGCAGCCCGCGCCCACGGTGCCGCAGGGGATCTCTGCTGATGCGGCGCCTGCGGTGGTGCACGGGGGCCCTGCTCCTGC
GGCTGCTGCGGTGCCGCAGGGGGTCTCTGCTGCTGCGCCTGTGGCGCCGCAGGGGGTCTCTGCCGCTGCTGTTCCGCAGC
CTGTCGCCGGCGCAGCCGCTTCTGCGAGCCCGGCCTCCGGCCCCGCGCCCGCGCCGGAACCGGCAGCGGCTCCGGCGGCA
GCCGTCTGGCCGGCGCTGTCGGATGCCGTCCCGGCGTCGCCTCTCTCCGGCATCCCGCTGCCCGGCAGCCCCGCCTCTGC
GGCCCTGGCCCCCGGCAGCGCGGATCTGGCCGGCCTGCGCCGGGAGATGGCCGACCTGCGGCAGGCGGTGACCCGGCTGG
TGGAGGCCCGGCCTGACCCCGCCGCTCTGCTGGAGCTGAAGGGCTACGCCCGCAAGGTCTACGAGCGGCTGCTGGACGCC
GGCGTGGCGGAAGGGCTGGCCCTGGCGATCAGCCGGAAGGTCGGCACCCACGCGACGAAGGGCAGGGCCCTTCTCCGGGC
GGAGCTGAACCAGCTCATGGGCCCCGGCGCGCCGATCCAGGCGGAGGCCGGCCGCCGGAGGGTGGTTGCGCTCATCGGCC
CCACCGGCGTGGGCAAGACCACGACGCTGGCCAAGCTGGCCGCGCACTTTGCCCTGGAGCGCGGGCTGAAGGTGGGGCTC
ATCACCGCCGACACCTTCCGCATCGCCGCCGTGGATCAGCTGCGCACGTACGCGGACATCCTGGCCATTCCCCTCTACAC
CGTGGAACGGCCGACCGACGTCCACCAGGCTCTGGCCCACAATGCGGACGCCGATCTGGTGCTCATGGACACCGGCGGCC
GGAGCCACAAGGACGAAGAGCGCATGGCGGAGCTGCAGGAACTTCTGGCGGAGGCGCAGCCCGACGAGGTGCACCTGGTG
GTCTCCCTGAATACCAACCCGCGGGACGTCCGCCGCATGCTGGAGCGCTACCTGCCGCTGGGCGTCAACCGCTTCATCTT
CACCAAGGCCGACGAGACCTCTGCCCCCGGACTGATGCTGAACATCCGGGCACAGTGGGACCTGCCGATCTCCTACGTGA
CCGACGGTCAGTCCGTGCCCGACGATCTGAGGCCCGCAGACAGCGTCGACTACTCCAAACTCTTCATGGGGGCGTAG

Upstream 100 bases:

>100_bases
TCGCCCAGCACACCTATCCGCGGCTGATCGTGCTCTCGTACGCGGAGCTTGATCCCAGGCTTGAGATCGAGTCGGTGGGG
GTGATCCGTGCATGATGCAG

Downstream 100 bases:

>100_bases
CCCGATGTTCGATCAAGCCAGCCGTCTGCGCGAACTGGCCGCTGCCTACCGGAATCAGGCCGCGGGCCGGGCGCCCCGTC
GCTTTGAGGCCATCGCGGTC

Product: flagellar GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MKKYMAPTYAEALILAKNELGTDAVIVDSRKVRVGGIFGLFGRVMTELTVAADQRPQPYRGARPAARPRGATAPSGAPAS
AQPAPTVPQGISADAAPAVVHGGPAPAAAAVPQGVSAAAPVAPQGVSAAAVPQPVAGAAASASPASGPAPAPEPAAAPAA
AVWPALSDAVPASPLSGIPLPGSPASAALAPGSADLAGLRREMADLRQAVTRLVEARPDPAALLELKGYARKVYERLLDA
GVAEGLALAISRKVGTHATKGRALLRAELNQLMGPGAPIQAEAGRRRVVALIGPTGVGKTTTLAKLAAHFALERGLKVGL
ITADTFRIAAVDQLRTYADILAIPLYTVERPTDVHQALAHNADADLVLMDTGGRSHKDEERMAELQELLAEAQPDEVHLV
VSLNTNPRDVRRMLERYLPLGVNRFIFTKADETSAPGLMLNIRAQWDLPISYVTDGQSVPDDLRPADSVDYSKLFMGA

Sequences:

>Translated_478_residues
MKKYMAPTYAEALILAKNELGTDAVIVDSRKVRVGGIFGLFGRVMTELTVAADQRPQPYRGARPAARPRGATAPSGAPAS
AQPAPTVPQGISADAAPAVVHGGPAPAAAAVPQGVSAAAPVAPQGVSAAAVPQPVAGAAASASPASGPAPAPEPAAAPAA
AVWPALSDAVPASPLSGIPLPGSPASAALAPGSADLAGLRREMADLRQAVTRLVEARPDPAALLELKGYARKVYERLLDA
GVAEGLALAISRKVGTHATKGRALLRAELNQLMGPGAPIQAEAGRRRVVALIGPTGVGKTTTLAKLAAHFALERGLKVGL
ITADTFRIAAVDQLRTYADILAIPLYTVERPTDVHQALAHNADADLVLMDTGGRSHKDEERMAELQELLAEAQPDEVHLV
VSLNTNPRDVRRMLERYLPLGVNRFIFTKADETSAPGLMLNIRAQWDLPISYVTDGQSVPDDLRPADSVDYSKLFMGA
>Mature_478_residues
MKKYMAPTYAEALILAKNELGTDAVIVDSRKVRVGGIFGLFGRVMTELTVAADQRPQPYRGARPAARPRGATAPSGAPAS
AQPAPTVPQGISADAAPAVVHGGPAPAAAAVPQGVSAAAPVAPQGVSAAAVPQPVAGAAASASPASGPAPAPEPAAAPAA
AVWPALSDAVPASPLSGIPLPGSPASAALAPGSADLAGLRREMADLRQAVTRLVEARPDPAALLELKGYARKVYERLLDA
GVAEGLALAISRKVGTHATKGRALLRAELNQLMGPGAPIQAEAGRRRVVALIGPTGVGKTTTLAKLAAHFALERGLKVGL
ITADTFRIAAVDQLRTYADILAIPLYTVERPTDVHQALAHNADADLVLMDTGGRSHKDEERMAELQELLAEAQPDEVHLV
VSLNTNPRDVRRMLERYLPLGVNRFIFTKADETSAPGLMLNIRAQWDLPISYVTDGQSVPDDLRPADSVDYSKLFMGA

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=223, Percent_Identity=28.6995515695067, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4507215, Length=269, Percent_Identity=27.1375464684015, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1789874, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788963, Length=180, Percent_Identity=31.6666666666667, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539958, Length=226, Percent_Identity=27.8761061946903, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325345, Length=271, Percent_Identity=26.1992619926199, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17647949, Length=210, Percent_Identity=32.8571428571429, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 49468; Mature: 49468

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYMAPTYAEALILAKNELGTDAVIVDSRKVRVGGIFGLFGRVMTELTVAADQRPQPYR
CCCCCCCHHHHEEEEECCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
GARPAARPRGATAPSGAPASAQPAPTVPQGISADAAPAVVHGGPAPAAAAVPQGVSAAAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCC
VAPQGVSAAAVPQPVAGAAASASPASGPAPAPEPAAAPAAAVWPALSDAVPASPLSGIPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
PGSPASAALAPGSADLAGLRREMADLRQAVTRLVEARPDPAALLELKGYARKVYERLLDA
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GVAEGLALAISRKVGTHATKGRALLRAELNQLMGPGAPIQAEAGRRRVVALIGPTGVGKT
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCH
TTLAKLAAHFALERGLKVGLITADTFRIAAVDQLRTYADILAIPLYTVERPTDVHQALAH
HHHHHHHHHHHHHCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHC
NADADLVLMDTGGRSHKDEERMAELQELLAEAQPDEVHLVVSLNTNPRDVRRMLERYLPL
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHCCC
GVNRFIFTKADETSAPGLMLNIRAQWDLPISYVTDGQSVPDDLRPADSVDYSKLFMGA
CCCEEEEEECCCCCCCCEEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKKYMAPTYAEALILAKNELGTDAVIVDSRKVRVGGIFGLFGRVMTELTVAADQRPQPYR
CCCCCCCHHHHEEEEECCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
GARPAARPRGATAPSGAPASAQPAPTVPQGISADAAPAVVHGGPAPAAAAVPQGVSAAAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCC
VAPQGVSAAAVPQPVAGAAASASPASGPAPAPEPAAAPAAAVWPALSDAVPASPLSGIPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
PGSPASAALAPGSADLAGLRREMADLRQAVTRLVEARPDPAALLELKGYARKVYERLLDA
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GVAEGLALAISRKVGTHATKGRALLRAELNQLMGPGAPIQAEAGRRRVVALIGPTGVGKT
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCH
TTLAKLAAHFALERGLKVGLITADTFRIAAVDQLRTYADILAIPLYTVERPTDVHQALAH
HHHHHHHHHHHHHCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHC
NADADLVLMDTGGRSHKDEERMAELQELLAEAQPDEVHLVVSLNTNPRDVRRMLERYLPL
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHCCC
GVNRFIFTKADETSAPGLMLNIRAQWDLPISYVTDGQSVPDDLRPADSVDYSKLFMGA
CCCEEEEEECCCCCCCCEEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168127; 9403685 [H]