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The map label for this gene is fliD [H]

Identifier: 51894113

GI number: 51894113

Start: 3198980

End: 3200410

Strand: Reverse

Name: fliD [H]

Synonym: STH2977

Alternate gene names: 51894113

Gene position: 3200410-3198980 (Counterclockwise)

Preceding gene: 51894114

Following gene: 51894112

Centisome position: 89.74

GC content: 61.5

Gene sequence:

>1431_bases
GTGAGCATGCGACTCGGCGGGCTCATCTCCGGCGCCGACACCGAGACGCTGATCTCGGCCCTGTTGGAGCTGGAACGGGT
CCGGATCTACCGGCAGGAGGAGAAGCAGGAACAGCTCGAGGCCAAGCAGAAGGCCTGGCGGGACGTCCGTTCGGCGCTCA
CCAACATCCAGTCCAAGCTGGACCAACTGCGCTTCCCGACGCTCTTCCGCTCCCGCAAGGTGGAGCTGAGTGACAATTCG
GTAGCGACCGTCACGGCCGACGCGGGTGCCGCCCAGACCAGCTACACCCTGCAGGTCGTGAAGCTGGCGCAGAGCCATGT
GATCACCACCCAGTCGGAGGCGGCCTACAAGGCGGCCGACGAGCAGCTGGGCTGGGCCGGCACGTTCGACATCGGGACGG
ATCCGAATGCGCTGAAGACCATCACCGTGGAGGAGACCGATACCCTGAGCTCCCTCGCGGCGAAGATCAACGCCGCCGAC
AGCGGCGTGCTGGCCCATGTCGTGATGGTGAGCGAAGGCAAGTTCCGGTTGGTACTCACCGCAGCCAAGTCCGGGTCGGC
GAACGTGATTCGGCTTGAAAATGAGGTTCCCGGGCAGCCGCCACAGGGGCAGACCTACGGCAACCTGCTGGAGGACATTC
TCGGCCTGACCGGTGCGAATCAACTGGTGCTTTCAGAGGCGCAGGATGCAGAAATCATTTTGAACGGTGAACCTTACAAG
AGTTCAACAAACACCTTTGACAACATCCTGCCGGGCATCAAGATTACCGTGAAGAAGCCCAGTGGGGACGATGTCGTCTC
CATGACCGTGTCCAGCGACATCGACAAGATCGTGCAGGTCGTCAAGGACTGGGTGAACGCGGTCAACTCGCTGCAGGACC
TGCTGAAGAAACTGAGCGCCTACGATGTGGAAAAGAAGACCGGGGCGGCCCTGACCGGCGAGAGCCTGGTGCGTTCGATC
CAGTCCCGCATGCGGCAGTTCTTCTCTACGGAAGTCGCCGGCATGCCGGCGTCGATGAAGATGCTCAGCCAGATCGGGGT
GTCCACCGGGGCCTACGGTACGGCCGACTTCGGCAAGATCGTCGTCGACGAGGAGAAGCTGAGGGAAGTGCTCCAGCGGG
ACCCGGAAGGCGTAGCCCGGCTGTTTGGACTGAACGAGGACGGCCAAAAAGGCATTGCCGTTCAGATGAATGACTACATC
AAGTCGCTTCTCGACAGTCAGTCGGGGGCACTTGAGGTTCGGGACAAAAGCCTGAGCCAGCAGATCGACCGAATCAGAGA
CACGATCGAGCGCATCGAGGTGCAGCTGGAGCAGCGGGAAAAAGTGTTGAGGCTCCAATTCGCCCGCATGGAAGAGGCGA
TGGCTAGGCTGCAAGGCCAGGGCAATTACCTCGCCCTGATGCTCCTGGGTCGTTCCCAGTCGCAGTCCTGA

Upstream 100 bases:

>100_bases
TGCTGCGGGAGTTCCCGCCGGAGCGGCTGCTGGAGGCGCTGCTGGCGATGGAGCGGTCCCTCGGCCTGCTGATTGACGAG
AAGGTCTAGGGGGTGGTCCC

Downstream 100 bases:

>100_bases
TGGAGGGAAGCGGGGATCACCATGGTGAGCGGGTTGAACCAGTACAAGGCGTATCAAGTGCAAACCACAGCCCCTGAGGA
TCAGGTGGCCCTGCTCTACG

Product: flagellar hook-associated protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSMRLGGLISGADTETLISALLELERVRIYRQEEKQEQLEAKQKAWRDVRSALTNIQSKLDQLRFPTLFRSRKVELSDNS
VATVTADAGAAQTSYTLQVVKLAQSHVITTQSEAAYKAADEQLGWAGTFDIGTDPNALKTITVEETDTLSSLAAKINAAD
SGVLAHVVMVSEGKFRLVLTAAKSGSANVIRLENEVPGQPPQGQTYGNLLEDILGLTGANQLVLSEAQDAEIILNGEPYK
SSTNTFDNILPGIKITVKKPSGDDVVSMTVSSDIDKIVQVVKDWVNAVNSLQDLLKKLSAYDVEKKTGAALTGESLVRSI
QSRMRQFFSTEVAGMPASMKMLSQIGVSTGAYGTADFGKIVVDEEKLREVLQRDPEGVARLFGLNEDGQKGIAVQMNDYI
KSLLDSQSGALEVRDKSLSQQIDRIRDTIERIEVQLEQREKVLRLQFARMEEAMARLQGQGNYLALMLLGRSQSQS

Sequences:

>Translated_476_residues
MSMRLGGLISGADTETLISALLELERVRIYRQEEKQEQLEAKQKAWRDVRSALTNIQSKLDQLRFPTLFRSRKVELSDNS
VATVTADAGAAQTSYTLQVVKLAQSHVITTQSEAAYKAADEQLGWAGTFDIGTDPNALKTITVEETDTLSSLAAKINAAD
SGVLAHVVMVSEGKFRLVLTAAKSGSANVIRLENEVPGQPPQGQTYGNLLEDILGLTGANQLVLSEAQDAEIILNGEPYK
SSTNTFDNILPGIKITVKKPSGDDVVSMTVSSDIDKIVQVVKDWVNAVNSLQDLLKKLSAYDVEKKTGAALTGESLVRSI
QSRMRQFFSTEVAGMPASMKMLSQIGVSTGAYGTADFGKIVVDEEKLREVLQRDPEGVARLFGLNEDGQKGIAVQMNDYI
KSLLDSQSGALEVRDKSLSQQIDRIRDTIERIEVQLEQREKVLRLQFARMEEAMARLQGQGNYLALMLLGRSQSQS
>Mature_475_residues
SMRLGGLISGADTETLISALLELERVRIYRQEEKQEQLEAKQKAWRDVRSALTNIQSKLDQLRFPTLFRSRKVELSDNSV
ATVTADAGAAQTSYTLQVVKLAQSHVITTQSEAAYKAADEQLGWAGTFDIGTDPNALKTITVEETDTLSSLAAKINAADS
GVLAHVVMVSEGKFRLVLTAAKSGSANVIRLENEVPGQPPQGQTYGNLLEDILGLTGANQLVLSEAQDAEIILNGEPYKS
STNTFDNILPGIKITVKKPSGDDVVSMTVSSDIDKIVQVVKDWVNAVNSLQDLLKKLSAYDVEKKTGAALTGESLVRSIQ
SRMRQFFSTEVAGMPASMKMLSQIGVSTGAYGTADFGKIVVDEEKLREVLQRDPEGVARLFGLNEDGQKGIAVQMNDYIK
SLLDSQSGALEVRDKSLSQQIDRIRDTIERIEVQLEQREKVLRLQFARMEEAMARLQGQGNYLALMLLGRSQSQS

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=494, Percent_Identity=26.7206477732794, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010810
- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07196 Flagellin_IN; PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 52045; Mature: 51914

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRLGGLISGADTETLISALLELERVRIYRQEEKQEQLEAKQKAWRDVRSALTNIQSKL
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLRFPTLFRSRKVELSDNSVATVTADAGAAQTSYTLQVVKLAQSHVITTQSEAAYKAAD
HHHCCCHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHH
EQLGWAGTFDIGTDPNALKTITVEETDTLSSLAAKINAADSGVLAHVVMVSEGKFRLVLT
HCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEE
AAKSGSANVIRLENEVPGQPPQGQTYGNLLEDILGLTGANQLVLSEAQDAEIILNGEPYK
ECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCC
SSTNTFDNILPGIKITVKKPSGDDVVSMTVSSDIDKIVQVVKDWVNAVNSLQDLLKKLSA
CCCCCHHHHCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDVEKKTGAALTGESLVRSIQSRMRQFFSTEVAGMPASMKMLSQIGVSTGAYGTADFGKI
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEE
VVDEEKLREVLQRDPEGVARLFGLNEDGQKGIAVQMNDYIKSLLDSQSGALEVRDKSLSQ
EECHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEHHHHHHH
QIDRIRDTIERIEVQLEQREKVLRLQFARMEEAMARLQGQGNYLALMLLGRSQSQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
SMRLGGLISGADTETLISALLELERVRIYRQEEKQEQLEAKQKAWRDVRSALTNIQSKL
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLRFPTLFRSRKVELSDNSVATVTADAGAAQTSYTLQVVKLAQSHVITTQSEAAYKAAD
HHHCCCHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHH
EQLGWAGTFDIGTDPNALKTITVEETDTLSSLAAKINAADSGVLAHVVMVSEGKFRLVLT
HCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEE
AAKSGSANVIRLENEVPGQPPQGQTYGNLLEDILGLTGANQLVLSEAQDAEIILNGEPYK
ECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCC
SSTNTFDNILPGIKITVKKPSGDDVVSMTVSSDIDKIVQVVKDWVNAVNSLQDLLKKLSA
CCCCCHHHHCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDVEKKTGAALTGESLVRSIQSRMRQFFSTEVAGMPASMKMLSQIGVSTGAYGTADFGKI
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEE
VVDEEKLREVLQRDPEGVARLFGLNEDGQKGIAVQMNDYIKSLLDSQSGALEVRDKSLSQ
EECHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEHHHHHHH
QIDRIRDTIERIEVQLEQREKVLRLQFARMEEAMARLQGQGNYLALMLLGRSQSQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8195064; 9384377 [H]