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The map label for this gene is fnr [H]

Identifier: 51894083

GI number: 51894083

Start: 3171159

End: 3171830

Strand: Reverse

Name: fnr [H]

Synonym: STH2947

Alternate gene names: 51894083

Gene position: 3171830-3171159 (Counterclockwise)

Preceding gene: 51894085

Following gene: 51894082

Centisome position: 88.94

GC content: 69.2

Gene sequence:

>672_bases
GTGCCCGATCTGGACTTCCTGCGGAGCCTTTCGCTCTTCCAAGGCTTGTCGGACGAGGAACTGGCCCGCATCGCCGCCAT
CGCGCGCGAGCGGCACTACCGCAAGGGGACGATTCTGTTCAACGAGGGCGACCCCGGCGAGGCCATCTACTTCATCAAGA
AGGGCCGCGTCCGCGTGTCGCGCCTTGCGGCGAACGGCCAGGAACAGGTGCTCCGGGTCTGGGGGCCGGGCCACGAGGTC
GGCCTGGTGGTGCTGGCCGACAAGGCGCCGTACCCGGCCACCGCGCAGGTCACCGAGGATTCGGTGCTCATCGCCTTCCG
GGTGGACGATCTGGTGCAGCTCCTGCCCGAGAGCCGAACGCTCGCGGCCAACGCCTTCTGCCTGGTGGGCCGCCGGCTGC
GGCTCGCGCGCGACACCGCCCACGAGCTGGCCGTGCACAACACCCACGGACGGCTGGCCGCCCTGCTGCTCCGGATGAAG
GCAGAGCAGGGGAGCGACGTCATCAACCTCGGCATGACCCACCAGGAGATCGCCGGAATGATCGGCACCAGTCGCGAGAC
CGTCACCCGGGTGCTGGGCGACTTCCGGCGCACGGGCTGCATTGCCGTGCAGGGCGAGTCGGTGGTCATCCGGGACGAGC
GCAAGCTGCGGGAGTGGATGGGAGAAAGCTGA

Upstream 100 bases:

>100_bases
ATAATGGATGGGGATCGCGGCCGCAATTGTGGGCAGCAGGGGCGCGGCGGCCCGCCGTCGTACCTATACAATCTGTTCCT
TTCCAGGAGGTGAGGCCGGC

Downstream 100 bases:

>100_bases
TCGGGCGGCGCAGGCGCGCCGCCCGTTTCCGTTGGTGACGGATATCACCGCGAACCGGCGCGCCGCGGCACGGGCGCGAC
GGCGGGCCGCGGGTACACTG

Product: putative cyclic nucleotide-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MPDLDFLRSLSLFQGLSDEELARIAAIARERHYRKGTILFNEGDPGEAIYFIKKGRVRVSRLAANGQEQVLRVWGPGHEV
GLVVLADKAPYPATAQVTEDSVLIAFRVDDLVQLLPESRTLAANAFCLVGRRLRLARDTAHELAVHNTHGRLAALLLRMK
AEQGSDVINLGMTHQEIAGMIGTSRETVTRVLGDFRRTGCIAVQGESVVIRDERKLREWMGES

Sequences:

>Translated_223_residues
MPDLDFLRSLSLFQGLSDEELARIAAIARERHYRKGTILFNEGDPGEAIYFIKKGRVRVSRLAANGQEQVLRVWGPGHEV
GLVVLADKAPYPATAQVTEDSVLIAFRVDDLVQLLPESRTLAANAFCLVGRRLRLARDTAHELAVHNTHGRLAALLLRMK
AEQGSDVINLGMTHQEIAGMIGTSRETVTRVLGDFRRTGCIAVQGESVVIRDERKLREWMGES
>Mature_222_residues
PDLDFLRSLSLFQGLSDEELARIAAIARERHYRKGTILFNEGDPGEAIYFIKKGRVRVSRLAANGQEQVLRVWGPGHEVG
LVVLADKAPYPATAQVTEDSVLIAFRVDDLVQLLPESRTLAANAFCLVGRRLRLARDTAHELAVHNTHGRLAALLLRMKA
EQGSDVINLGMTHQEIAGMIGTSRETVTRVLGDFRRTGCIAVQGESVVIRDERKLREWMGES

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=217, Percent_Identity=27.6497695852535, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789756, Length=190, Percent_Identity=24.7368421052632, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 24753; Mature: 24622

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLDFLRSLSLFQGLSDEELARIAAIARERHYRKGTILFNEGDPGEAIYFIKKGRVRVS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCEEEE
RLAANGQEQVLRVWGPGHEVGLVVLADKAPYPATAQVTEDSVLIAFRVDDLVQLLPESRT
HHHCCCHHHEEEEECCCCEEEEEEEECCCCCCCEEEECCCCEEEEEEHHHHHHHCCCCCC
LAANAFCLVGRRLRLARDTAHELAVHNTHGRLAALLLRMKAEQGSDVINLGMTHQEIAGM
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
IGTSRETVTRVLGDFRRTGCIAVQGESVVIRDERKLREWMGES
HCCCHHHHHHHHHHHHHCCEEEEECCEEEEECHHHHHHHCCCC
>Mature Secondary Structure 
PDLDFLRSLSLFQGLSDEELARIAAIARERHYRKGTILFNEGDPGEAIYFIKKGRVRVS
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCEEEE
RLAANGQEQVLRVWGPGHEVGLVVLADKAPYPATAQVTEDSVLIAFRVDDLVQLLPESRT
HHHCCCHHHEEEEECCCCEEEEEEEECCCCCCCEEEECCCCEEEEEEHHHHHHHCCCCCC
LAANAFCLVGRRLRLARDTAHELAVHNTHGRLAALLLRMKAEQGSDVINLGMTHQEIAGM
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
IGTSRETVTRVLGDFRRTGCIAVQGESVVIRDERKLREWMGES
HCCCHHHHHHHHHHHHHCCEEEEECCEEEEECHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]