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The map label for this gene is selA [H]

Identifier: 51893729

GI number: 51893729

Start: 2778508

End: 2779908

Strand: Reverse

Name: selA [H]

Synonym: STH2591

Alternate gene names: 51893729

Gene position: 2779908-2778508 (Counterclockwise)

Preceding gene: 51893731

Following gene: 51893728

Centisome position: 77.95

GC content: 73.95

Gene sequence:

>1401_bases
ATGAAGCCATGGCAGCAGTCGGCGCTGCGCGCCATCCCGCCGGTCAACGAGATTCTGGAGACGCCCACCGGCCAGCGGCT
GCTGGCCGAGCGCGCCCGCGCCCTGGTGGTGGACGCGGTGGGCGAGGCCCTGGACGCCCTGCGCAGGAAGATCGCGGCCG
CGGCCAGCGAGGAGGAGCTGGCCGTCCTGGACCGCAGCCCCGAGGGGCTGGCGGCCGACGCCGCGGCGCGCCTCAGCCGG
AGGCTGAGGCCCCGGCTGCGCCGGGTGATCAACGCGACCGGCGTGGTGATTCACACCAACATGGGCCGGGCGCCCCTGGC
GGAGGAGGCGGTGGCGGCCATCGTCGACATCGCGGGGCGGTACAACAACCTGGAGCTGGACCTCTCCACCGGCGAGCGGG
GCTCCCGCTACGCCCACGTGGAGGCGCTGCTGGCCGAGCTTACCGGCGCCGAGGCGGCCATGGTGGTGAACAACAACGCC
GCCGCGGTGCTGCTCATGCTCTCCGCCCTGGCGGCGGGGAAGGAGGTCGTCGTCTCCCGCGGCGAGCTGGTGGAGATCGG
CGGCTCCTTCCGGGTGCCGGACGTGATGAAGCAGGGCGGCGCCCGGCTGGTGGAGGTGGGCACCACCAACAAGACCCACC
CCCGGGACTACGAGGAGGCCATCGGTCCGGAGACCTGCGCGCTGCTGAAGGTGCACCGGTCCAACTTCCGGCTGGAGGGC
TTCACCGCCGAGGTCTCGGTGGCGGAGCTGGCCCGGATCGCCCACCGGCACGGGCTGCCGTGCCTGGTGGACTGGGGCTC
GGGGGTCATGCTGGACCTCTCCCGCTACGGGCTGCCGCACGAGGCGACCATGCCCGAGCTCATCGCCGCCGGCGCCGACC
TGGTCACCTTCTCCGGGGACAAGCTGCTGGGCGCGCCCCAGGGCGGCTTCATCGTCGGCCGGCGGGACCTGGTGGAGCGG
TGCCGCAGGCACCCGCTCACCCGCGCCGTGCGGGTGGACAAGCTGACGCTGGCCGGTATAGAGGCCACCCTGAAGCTGTA
CCTGGAGCCTGAGCGGGCCGCGGAACGGATTCCGGCGGTGCGCATGCTCACCGCCTCCCGGGAGCAGATCGCCCCCCGGG
CCGAGGCCCTGGCCGGCAAGCTGAGGGCGGCCGGCATCGCCTGCGAGGTCATCGACGGCGTCTCCCGGGCCGGCGGCGGC
GCCCTGCCGGGCGTCGACCTGCCCACCCGCCTGGTGGCGGTCGCCCACCCGGCGCCGCAGGAGGTGGAGGCCCGCCTGCG
CGCCTTCGACCCGCCGGTGATGGTGCGCATCCAGGCGGGGCTCCTGCTCCTCGATCCGCGCACGCTCTGGGACGACGAAC
TGGACGTGGTGGTATCTGCCCTGCGGTCCGCCATCGTCTAA

Upstream 100 bases:

>100_bases
TTTCTTCCTCTTTCCAACCAGACTTGGCCCCTGCACATGCAACAGCTTATAATTGGAGGCGACCTGAACTTCAGATGCCG
GGCGATCGGAGGAACGGAAC

Downstream 100 bases:

>100_bases
CTGCTGGGGAGGTGAACCCGATGCGGCTGACCGGTCCCGACGACACCATCCGGCTGACCCAGTACACCGCCAAGTCCGGC
TGAGGCTGCAAGATAGGTCC

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKPWQQSALRAIPPVNEILETPTGQRLLAERARALVVDAVGEALDALRRKIAAAASEEELAVLDRSPEGLAADAAARLSR
RLRPRLRRVINATGVVIHTNMGRAPLAEEAVAAIVDIAGRYNNLELDLSTGERGSRYAHVEALLAELTGAEAAMVVNNNA
AAVLLMLSALAAGKEVVVSRGELVEIGGSFRVPDVMKQGGARLVEVGTTNKTHPRDYEEAIGPETCALLKVHRSNFRLEG
FTAEVSVAELARIAHRHGLPCLVDWGSGVMLDLSRYGLPHEATMPELIAAGADLVTFSGDKLLGAPQGGFIVGRRDLVER
CRRHPLTRAVRVDKLTLAGIEATLKLYLEPERAAERIPAVRMLTASREQIAPRAEALAGKLRAAGIACEVIDGVSRAGGG
ALPGVDLPTRLVAVAHPAPQEVEARLRAFDPPVMVRIQAGLLLLDPRTLWDDELDVVVSALRSAIV

Sequences:

>Translated_466_residues
MKPWQQSALRAIPPVNEILETPTGQRLLAERARALVVDAVGEALDALRRKIAAAASEEELAVLDRSPEGLAADAAARLSR
RLRPRLRRVINATGVVIHTNMGRAPLAEEAVAAIVDIAGRYNNLELDLSTGERGSRYAHVEALLAELTGAEAAMVVNNNA
AAVLLMLSALAAGKEVVVSRGELVEIGGSFRVPDVMKQGGARLVEVGTTNKTHPRDYEEAIGPETCALLKVHRSNFRLEG
FTAEVSVAELARIAHRHGLPCLVDWGSGVMLDLSRYGLPHEATMPELIAAGADLVTFSGDKLLGAPQGGFIVGRRDLVER
CRRHPLTRAVRVDKLTLAGIEATLKLYLEPERAAERIPAVRMLTASREQIAPRAEALAGKLRAAGIACEVIDGVSRAGGG
ALPGVDLPTRLVAVAHPAPQEVEARLRAFDPPVMVRIQAGLLLLDPRTLWDDELDVVVSALRSAIV
>Mature_466_residues
MKPWQQSALRAIPPVNEILETPTGQRLLAERARALVVDAVGEALDALRRKIAAAASEEELAVLDRSPEGLAADAAARLSR
RLRPRLRRVINATGVVIHTNMGRAPLAEEAVAAIVDIAGRYNNLELDLSTGERGSRYAHVEALLAELTGAEAAMVVNNNA
AAVLLMLSALAAGKEVVVSRGELVEIGGSFRVPDVMKQGGARLVEVGTTNKTHPRDYEEAIGPETCALLKVHRSNFRLEG
FTAEVSVAELARIAHRHGLPCLVDWGSGVMLDLSRYGLPHEATMPELIAAGADLVTFSGDKLLGAPQGGFIVGRRDLVER
CRRHPLTRAVRVDKLTLAGIEATLKLYLEPERAAERIPAVRMLTASREQIAPRAEALAGKLRAAGIACEVIDGVSRAGGG
ALPGVDLPTRLVAVAHPAPQEVEARLRAFDPPVMVRIQAGLLLLDPRTLWDDELDVVVSALRSAIV

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=461, Percent_Identity=44.9023861171367, Blast_Score=317, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 49832; Mature: 49832

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPWQQSALRAIPPVNEILETPTGQRLLAERARALVVDAVGEALDALRRKIAAAASEEEL
CCCHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
AVLDRSPEGLAADAAARLSRRLRPRLRRVINATGVVIHTNMGRAPLAEEAVAAIVDIAGR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCC
YNNLELDLSTGERGSRYAHVEALLAELTGAEAAMVVNNNAAAVLLMLSALAAGKEVVVSR
CCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCHHEECC
GELVEIGGSFRVPDVMKQGGARLVEVGTTNKTHPRDYEEAIGPETCALLKVHRSNFRLEG
CCEEEECCCCCCCHHHHCCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHEEHHCCEEEEC
FTAEVSVAELARIAHRHGLPCLVDWGSGVMLDLSRYGLPHEATMPELIAAGADLVTFSGD
EEEHHHHHHHHHHHHHCCCCEEEECCCCEEEEHHHCCCCCCCCCHHHHHCCCCEEEECCC
KLLGAPQGGFIVGRRDLVERCRRHPLTRAVRVDKLTLAGIEATLKLYLEPERAAERIPAV
EEECCCCCCEEECCHHHHHHHHHCCHHHHHHHHHEEEHHHEEEEEEEECCHHHHHHCCHH
RMLTASREQIAPRAEALAGKLRAAGIACEVIDGVSRAGGGALPGVDLPTRLVAVAHPAPQ
HHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEECCCCCH
EVEARLRAFDPPVMVRIQAGLLLLDPRTLWDDELDVVVSALRSAIV
HHHHHHHHCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPWQQSALRAIPPVNEILETPTGQRLLAERARALVVDAVGEALDALRRKIAAAASEEEL
CCCHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
AVLDRSPEGLAADAAARLSRRLRPRLRRVINATGVVIHTNMGRAPLAEEAVAAIVDIAGR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCC
YNNLELDLSTGERGSRYAHVEALLAELTGAEAAMVVNNNAAAVLLMLSALAAGKEVVVSR
CCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCHHEECC
GELVEIGGSFRVPDVMKQGGARLVEVGTTNKTHPRDYEEAIGPETCALLKVHRSNFRLEG
CCEEEECCCCCCCHHHHCCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHEEHHCCEEEEC
FTAEVSVAELARIAHRHGLPCLVDWGSGVMLDLSRYGLPHEATMPELIAAGADLVTFSGD
EEEHHHHHHHHHHHHHCCCCEEEECCCCEEEEHHHCCCCCCCCCHHHHHCCCCEEEECCC
KLLGAPQGGFIVGRRDLVERCRRHPLTRAVRVDKLTLAGIEATLKLYLEPERAAERIPAV
EEECCCCCCEEECCHHHHHHHHHCCHHHHHHHHHEEEHHHEEEEEEEECCHHHHHHCCHH
RMLTASREQIAPRAEALAGKLRAAGIACEVIDGVSRAGGGALPGVDLPTRLVAVAHPAPQ
HHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEECCCCCH
EVEARLRAFDPPVMVRIQAGLLLLDPRTLWDDELDVVVSALRSAIV
HHHHHHHHCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA