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The map label for this gene is selD1 [H]

Identifier: 51893728

GI number: 51893728

Start: 2777420

End: 2778391

Strand: Reverse

Name: selD1 [H]

Synonym: STH2590

Alternate gene names: 51893728

Gene position: 2778391-2777420 (Counterclockwise)

Preceding gene: 51893729

Following gene: 51893727

Centisome position: 77.91

GC content: 70.37

Gene sequence:

>972_bases
GTGCTCCGGCACCTGCCTCCGTCCCTGACCAACGCCGACGTCATCGTCGGCCTCGACACGCCGGATGACGCCGGGGTCTA
CCGCATCACCGACGACCTGGCCCTGGTGCAGACGGCGGACTTCTTTACGCCCATCGTCGACGATCCCTACTGGTTCGGCG
CCATCGCCGCAGCCAACAGCCTGTCGGACATCTACGCGATGGGCGGGCGGCCGGTCACGGCGCTCAACCTCGTCAGCTTC
CCCGTCAGCAAGCTGGACAAGCGCATCCTCGCGGAGATCCTGCGGGGCGGTGCGGAGAAGGTGGCTGAGGCGGGCGCGGT
GCTCATCGGCGGCCACTCCATCGACGGCCCCGAGCCCACCTACGGGCTGGCGGTCACCGGGCTCGTCCACCCGGACCGGG
TGGGGGCGAAGGCCGGCGTGCGGCCGGGGGACCGGCTGATCCTGACCAAGCCCATCGGGGTCGGCGTCATTACCACGGCC
ATCAAGCGGGGGCTCGCCCGGCCGGCGGACGTCGACGAGGTGACGCAGGTCATGGCGAAGCTGAACAACGTGGTGGACGT
ACTCGCGCCCTTCGACATCCGCGGCATGACCGACATCACCGGCTTCGGCCTCCTGGGCCACGCCTCGGAGATGGCCCGCA
CCAGCGGCGTGGGGCTGCGCCTCTCGGCCGGCGCCGTGCCGGTGCTGCCGTCGACCTATGACTACGCCGAACAGGGCGCC
TTCCCCGGCGGCTCCAAGGCCAACTTCCGGTTCCTGACCGGCGAGGGGCACGTGGAGTTCGCCGAGTCGGTGCCTGAGCT
GGTGCGGATGATCCTTTGCGACGCGGTCACCTCCGGCGGCCTGCTGATCGCGGTGGAGGCCGCGCGGGCCGCGGATCTGG
CTTCAGCCCTTACAGCACACGGGACGCTGGCCGCTGCCGTCATCGGCGAGGCGGTGGCCGAGCATCCCGGGAAGATCATG
GTGATAGACTGA

Upstream 100 bases:

>100_bases
CCCGATGCGGCTGACCGGTCCCGACGACACCATCCGGCTGACCCAGTACACCGCCAAGTCCGGCTGAGGCTGCAAGATAG
GTCCGGCGGACCTATCCGAG

Downstream 100 bases:

>100_bases
TGCATATTGAACGGGTGCCGGGTATTGCCCTGAGCCCCAGCGGCGCGGTTGCGGCCTACCTGGGCGACTGGGCGCGCGTG
GCTCCTGCGTATGAGTACGA

Product: selenophosphate synthetase

Products: NA

Alternate protein names: Selenium donor protein 1; Selenophosphate synthase 1 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MLRHLPPSLTNADVIVGLDTPDDAGVYRITDDLALVQTADFFTPIVDDPYWFGAIAAANSLSDIYAMGGRPVTALNLVSF
PVSKLDKRILAEILRGGAEKVAEAGAVLIGGHSIDGPEPTYGLAVTGLVHPDRVGAKAGVRPGDRLILTKPIGVGVITTA
IKRGLARPADVDEVTQVMAKLNNVVDVLAPFDIRGMTDITGFGLLGHASEMARTSGVGLRLSAGAVPVLPSTYDYAEQGA
FPGGSKANFRFLTGEGHVEFAESVPELVRMILCDAVTSGGLLIAVEAARAADLASALTAHGTLAAAVIGEAVAEHPGKIM
VID

Sequences:

>Translated_323_residues
MLRHLPPSLTNADVIVGLDTPDDAGVYRITDDLALVQTADFFTPIVDDPYWFGAIAAANSLSDIYAMGGRPVTALNLVSF
PVSKLDKRILAEILRGGAEKVAEAGAVLIGGHSIDGPEPTYGLAVTGLVHPDRVGAKAGVRPGDRLILTKPIGVGVITTA
IKRGLARPADVDEVTQVMAKLNNVVDVLAPFDIRGMTDITGFGLLGHASEMARTSGVGLRLSAGAVPVLPSTYDYAEQGA
FPGGSKANFRFLTGEGHVEFAESVPELVRMILCDAVTSGGLLIAVEAARAADLASALTAHGTLAAAVIGEAVAEHPGKIM
VID
>Mature_323_residues
MLRHLPPSLTNADVIVGLDTPDDAGVYRITDDLALVQTADFFTPIVDDPYWFGAIAAANSLSDIYAMGGRPVTALNLVSF
PVSKLDKRILAEILRGGAEKVAEAGAVLIGGHSIDGPEPTYGLAVTGLVHPDRVGAKAGVRPGDRLILTKPIGVGVITTA
IKRGLARPADVDEVTQVMAKLNNVVDVLAPFDIRGMTDITGFGLLGHASEMARTSGVGLRLSAGAVPVLPSTYDYAEQGA
FPGGSKANFRFLTGEGHVEFAESVPELVRMILCDAVTSGGLLIAVEAARAADLASALTAHGTLAAAVIGEAVAEHPGKIM
VID

Specific function: Synthesizes selenophosphate from selenide and ATP [H]

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily [H]

Homologues:

Organism=Homo sapiens, GI24797148, Length=288, Percent_Identity=30.2083333333333, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI15011844, Length=288, Percent_Identity=30.2083333333333, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1788062, Length=315, Percent_Identity=44.1269841269841, Blast_Score=248, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI17543426, Length=301, Percent_Identity=30.2325581395349, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653602, Length=298, Percent_Identity=30.8724832214765, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24653604, Length=298, Percent_Identity=30.8724832214765, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574119, Length=229, Percent_Identity=27.9475982532751, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574118, Length=206, Percent_Identity=30.5825242718447, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.9.3 [H]

Molecular weight: Translated: 33421; Mature: 33421

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRHLPPSLTNADVIVGLDTPDDAGVYRITDDLALVQTADFFTPIVDDPYWFGAIAAANS
CCCCCCCCCCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LSDIYAMGGRPVTALNLVSFPVSKLDKRILAEILRGGAEKVAEAGAVLIGGHSIDGPEPT
HHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCCC
YGLAVTGLVHPDRVGAKAGVRPGDRLILTKPIGVGVITTAIKRGLARPADVDEVTQVMAK
CCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
LNNVVDVLAPFDIRGMTDITGFGLLGHASEMARTSGVGLRLSAGAVPVLPSTYDYAEQGA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHCC
FPGGSKANFRFLTGEGHVEFAESVPELVRMILCDAVTSGGLLIAVEAARAADLASALTAH
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHH
GTLAAAVIGEAVAEHPGKIMVID
HHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MLRHLPPSLTNADVIVGLDTPDDAGVYRITDDLALVQTADFFTPIVDDPYWFGAIAAANS
CCCCCCCCCCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LSDIYAMGGRPVTALNLVSFPVSKLDKRILAEILRGGAEKVAEAGAVLIGGHSIDGPEPT
HHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCCC
YGLAVTGLVHPDRVGAKAGVRPGDRLILTKPIGVGVITTAIKRGLARPADVDEVTQVMAK
CCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
LNNVVDVLAPFDIRGMTDITGFGLLGHASEMARTSGVGLRLSAGAVPVLPSTYDYAEQGA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHCC
FPGGSKANFRFLTGEGHVEFAESVPELVRMILCDAVTSGGLLIAVEAARAADLASALTAH
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHH
GTLAAAVIGEAVAEHPGKIMVID
HHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11041351 [H]