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The map label for this gene is ttdA [C]

Identifier: 51893674

GI number: 51893674

Start: 2720510

End: 2721352

Strand: Reverse

Name: ttdA [C]

Synonym: STH2536

Alternate gene names: 51893674

Gene position: 2721352-2720510 (Counterclockwise)

Preceding gene: 51893675

Following gene: 51893673

Centisome position: 76.31

GC content: 67.97

Gene sequence:

>843_bases
GTGCGGGAGATTCACGTGGACCAGGTGGCCGACGCCGTCGCCCGCCTGGTGCAGGAGGCGAATTTCAAGCTTTCGGATGA
CGTGGTCCGGGCCCTCTCGCAGGCGCAGTCGCTGGAGGAGGCCCCCGTGGGCCAGACGGTGCTCCTGCAGATCGTCGAGA
ACTACACCATCGCCGAGACCGAGCAGGTGCCGATGTGCCAGGACACCGGCGTGGCCCTGGTCTTCCTGGAGATCGGGCAG
GACGTGCACCTGGTGGGCGGGGACCTGTACGAGGCGATCAACCGGGGCGTCGCCCGGGGCTACACCGAGGGCAGGCTCCG
CATGTCGATGCTGAACGACCCGATCAAGCGGGTCAACACCCGGGACAATACCCCGGCGATGATCTACGTCGACATCGTGC
CCGGCGACCAGCTCAGAATCAAGGTCGACACCAAGGGCGGCGGGTCCGAGAACATGAGCCAGCTGAAGATGCTGCCGCCT
TCCGCCGGATGGGAGGGCGCGAAGCGGTTCATCGTGGAGACCGTGGCCGCAGCCGGCCCCAATGCCTGCCCGCCGCTGGT
GGTCGGCGTGGGCATCGGCGGCAACTTCGACAAGTGCGCCCTGCTGGCCAAGAAGGCGCTGCTGCGTGAGGTGGGCGCGC
CGAATCCCGATCCCGAGTGGGCCGCCCGGGAGCAGGAGCTGCTCACGGAGATCAACAAGCTGGGCGTCGGCCCGATGGGG
CTCGGCGGTACCGTGACCGCCCTGGCCGTGCACATTGAGGTCATGGGCTGCCACATCACCGCCCTGCCCGTGGCCGTGAA
CATCGAGTGCCACAGCCACCGGCACAAGGAGGTGACGCTCTGA

Upstream 100 bases:

>100_bases
AGGGCTGACTTGTGTGACCCGATTTGCTACAGTGGGGGTAGGTAGAATTCGCCCCTCTGTATATCCTGGGGTAGACCGGG
CGCATGAGGAGGAGGAAGCT

Downstream 100 bases:

>100_bases
TGGCCCGCGTCCACATCACCACGCCCGTCACCCCGGAGCAGGTGCGCCAGATCCGGGCCGGCGACGAGGTGATCATCACC
GGCGAGATCTACACGGCCCG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MREIHVDQVADAVARLVQEANFKLSDDVVRALSQAQSLEEAPVGQTVLLQIVENYTIAETEQVPMCQDTGVALVFLEIGQ
DVHLVGGDLYEAINRGVARGYTEGRLRMSMLNDPIKRVNTRDNTPAMIYVDIVPGDQLRIKVDTKGGGSENMSQLKMLPP
SAGWEGAKRFIVETVAAAGPNACPPLVVGVGIGGNFDKCALLAKKALLREVGAPNPDPEWAAREQELLTEINKLGVGPMG
LGGTVTALAVHIEVMGCHITALPVAVNIECHSHRHKEVTL

Sequences:

>Translated_280_residues
MREIHVDQVADAVARLVQEANFKLSDDVVRALSQAQSLEEAPVGQTVLLQIVENYTIAETEQVPMCQDTGVALVFLEIGQ
DVHLVGGDLYEAINRGVARGYTEGRLRMSMLNDPIKRVNTRDNTPAMIYVDIVPGDQLRIKVDTKGGGSENMSQLKMLPP
SAGWEGAKRFIVETVAAAGPNACPPLVVGVGIGGNFDKCALLAKKALLREVGAPNPDPEWAAREQELLTEINKLGVGPMG
LGGTVTALAVHIEVMGCHITALPVAVNIECHSHRHKEVTL
>Mature_280_residues
MREIHVDQVADAVARLVQEANFKLSDDVVRALSQAQSLEEAPVGQTVLLQIVENYTIAETEQVPMCQDTGVALVFLEIGQ
DVHLVGGDLYEAINRGVARGYTEGRLRMSMLNDPIKRVNTRDNTPAMIYVDIVPGDQLRIKVDTKGGGSENMSQLKMLPP
SAGWEGAKRFIVETVAAAGPNACPPLVVGVGIGGNFDKCALLAKKALLREVGAPNPDPEWAAREQELLTEINKLGVGPMG
LGGTVTALAVHIEVMGCHITALPVAVNIECHSHRHKEVTL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=273, Percent_Identity=33.3333333333333, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790564, Length=286, Percent_Identity=32.5174825174825, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787897, Length=247, Percent_Identity=33.6032388663968, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30082; Mature: 30082

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIHVDQVADAVARLVQEANFKLSDDVVRALSQAQSLEEAPVGQTVLLQIVENYTIAET
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
EQVPMCQDTGVALVFLEIGQDVHLVGGDLYEAINRGVARGYTEGRLRMSMLNDPIKRVNT
CCCCCCCCCCEEEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCEEHHHHHCHHHHCCC
RDNTPAMIYVDIVPGDQLRIKVDTKGGGSENMSQLKMLPPSAGWEGAKRFIVETVAAAGP
CCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHCCC
NACPPLVVGVGIGGNFDKCALLAKKALLREVGAPNPDPEWAAREQELLTEINKLGVGPMG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
LGGTVTALAVHIEVMGCHITALPVAVNIECHSHRHKEVTL
CCHHHHHHEEEEEEEEEEEEEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MREIHVDQVADAVARLVQEANFKLSDDVVRALSQAQSLEEAPVGQTVLLQIVENYTIAET
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
EQVPMCQDTGVALVFLEIGQDVHLVGGDLYEAINRGVARGYTEGRLRMSMLNDPIKRVNT
CCCCCCCCCCEEEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCEEHHHHHCHHHHCCC
RDNTPAMIYVDIVPGDQLRIKVDTKGGGSENMSQLKMLPPSAGWEGAKRFIVETVAAAGP
CCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHCCC
NACPPLVVGVGIGGNFDKCALLAKKALLREVGAPNPDPEWAAREQELLTEINKLGVGPMG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
LGGTVTALAVHIEVMGCHITALPVAVNIECHSHRHKEVTL
CCHHHHHHEEEEEEEEEEEEEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]