Click here to switch to the map view.

The map label for this gene is dagK [H]

Identifier: 51893562

GI number: 51893562

Start: 2608672

End: 2609556

Strand: Reverse

Name: dagK [H]

Synonym: STH2424

Alternate gene names: 51893562

Gene position: 2609556-2608672 (Counterclockwise)

Preceding gene: 51893563

Following gene: 51893561

Centisome position: 73.18

GC content: 72.66

Gene sequence:

>885_bases
ATGGCCTTCCGGCGCATTGCGGTCATCTACAATCCGGCCTCCGGGCGGCCCCGGGAGCGGGAGGAGCCGCTGGCCCGGCT
GGCGGCGCCCCTGCGCGCAGCCGGCTGCGAGGTGGCCATCTGCCCCACGGCGCGGCCCGGCCACGCGACCGAGATCGCGC
AGGCGAGGGCCGGGGAAGGGTACGACCTGATCCTCGCCCACGGCGGCGACGGCACCATGAACGAGGCGCTGCAGGGGGTG
ATGGGCACCGGGGCGGCTCTGGGCTTCTGGCCCGGCGGCACCGCGAACGTGCTGGCCGCCGAGCTGCACCTTCCGCACCG
GCCGGAGGAGATGGCCAGGCGGATCCGCGACGGGCGGACCGCGGAGGTGACGGTGGGCCGGGCCAACGACCGGTACTTCC
TGCTGATGGCCGGGGTCGGCCTGGACGCGGCGGTGGCCGGTTCGGTGGATCCCGAGCTCAAGCGCCGGTTTGGGAAGGCG
GCCTTCTTCGTGGCCGCCATGCAGTTCATCTGGCGGTGGGAGCTGGCGCCGTTCGTCGTGCACCTGGACGGCGAGCCGCC
GGTGGAGGGCCGGTTCGTGGTGGCGGGCAACGCCCGCTCCTACGGTGGCGGCTTCCAGTTCACGCCGGACGCCTCCCTCA
CCGACCCTGACCTGGACGTCTGCATCTTCACCGCAGAGGCGGTGGGAGACTACCTGCGCTACGTCTCGGCCGCGCTGGTG
GGGCTGCACCGGAACCTGCCCGGGGTGATCTACCGCAAGGCGCGCAGGGTGTCGATTACGGCGGCCGCCGAACACGCCCC
CCTCACCCAGGTGGACGGCGAGGTCATCGGCAGCCTGCCGGTGACCCTGGAGTCGATTCCGCGGGCCCTGAGACTTTTGG
TTTAG

Upstream 100 bases:

>100_bases
CCCCAACGACCCGCAGGCGTACGTGGAGCGGGTCGAGGAGCTGGCCCGGCGGAAGGTCGCGGAGCTCAGGCTGCTCTACG
GCGAGTAGGGGGTGGCGCGC

Downstream 100 bases:

>100_bases
GGTATTGACAGCCCGTGGCCAGAGAAGTAGAATCCAGGATCAAAGGCGATGACAGGGAGCAGGGCTCCGCACGGGCCCCC
TGCAGAGAGCCGGCCCTCAG

Product: hypothetical protein

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAFRRIAVIYNPASGRPREREEPLARLAAPLRAAGCEVAICPTARPGHATEIAQARAGEGYDLILAHGGDGTMNEALQGV
MGTGAALGFWPGGTANVLAAELHLPHRPEEMARRIRDGRTAEVTVGRANDRYFLLMAGVGLDAAVAGSVDPELKRRFGKA
AFFVAAMQFIWRWELAPFVVHLDGEPPVEGRFVVAGNARSYGGGFQFTPDASLTDPDLDVCIFTAEAVGDYLRYVSAALV
GLHRNLPGVIYRKARRVSITAAAEHAPLTQVDGEVIGSLPVTLESIPRALRLLV

Sequences:

>Translated_294_residues
MAFRRIAVIYNPASGRPREREEPLARLAAPLRAAGCEVAICPTARPGHATEIAQARAGEGYDLILAHGGDGTMNEALQGV
MGTGAALGFWPGGTANVLAAELHLPHRPEEMARRIRDGRTAEVTVGRANDRYFLLMAGVGLDAAVAGSVDPELKRRFGKA
AFFVAAMQFIWRWELAPFVVHLDGEPPVEGRFVVAGNARSYGGGFQFTPDASLTDPDLDVCIFTAEAVGDYLRYVSAALV
GLHRNLPGVIYRKARRVSITAAAEHAPLTQVDGEVIGSLPVTLESIPRALRLLV
>Mature_293_residues
AFRRIAVIYNPASGRPREREEPLARLAAPLRAAGCEVAICPTARPGHATEIAQARAGEGYDLILAHGGDGTMNEALQGVM
GTGAALGFWPGGTANVLAAELHLPHRPEEMARRIRDGRTAEVTVGRANDRYFLLMAGVGLDAAVAGSVDPELKRRFGKAA
FFVAAMQFIWRWELAPFVVHLDGEPPVEGRFVVAGNARSYGGGFQFTPDASLTDPDLDVCIFTAEAVGDYLRYVSAALVG
LHRNLPGVIYRKARRVSITAAAEHAPLTQVDGEVIGSLPVTLESIPRALRLLV

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=279, Percent_Identity=25.4480286738351, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 31473; Mature: 31342

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRRIAVIYNPASGRPREREEPLARLAAPLRAAGCEVAICPTARPGHATEIAQARAGEG
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCC
YDLILAHGGDGTMNEALQGVMGTGAALGFWPGGTANVLAAELHLPHRPEEMARRIRDGRT
EEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHEEEEEECCCCCHHHHHHHHHCCCE
AEVTVGRANDRYFLLMAGVGLDAAVAGSVDPELKRRFGKAAFFVAAMQFIWRWELAPFVV
EEEEEECCCCEEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
HLDGEPPVEGRFVVAGNARSYGGGFQFTPDASLTDPDLDVCIFTAEAVGDYLRYVSAALV
EECCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
GLHRNLPGVIYRKARRVSITAAAEHAPLTQVDGEVIGSLPVTLESIPRALRLLV
HHHCCCCHHHHHHCCEEEEEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AFRRIAVIYNPASGRPREREEPLARLAAPLRAAGCEVAICPTARPGHATEIAQARAGEG
CCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCC
YDLILAHGGDGTMNEALQGVMGTGAALGFWPGGTANVLAAELHLPHRPEEMARRIRDGRT
EEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHEEEEEECCCCCHHHHHHHHHCCCE
AEVTVGRANDRYFLLMAGVGLDAAVAGSVDPELKRRFGKAAFFVAAMQFIWRWELAPFVV
EEEEEECCCCEEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
HLDGEPPVEGRFVVAGNARSYGGGFQFTPDASLTDPDLDVCIFTAEAVGDYLRYVSAALV
EECCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
GLHRNLPGVIYRKARRVSITAAAEHAPLTQVDGEVIGSLPVTLESIPRALRLLV
HHHCCCCHHHHHHCCEEEEEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]