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The map label for this gene is yhaO [H]

Identifier: 51893445

GI number: 51893445

Start: 2491067

End: 2492188

Strand: Reverse

Name: yhaO [H]

Synonym: STH2307

Alternate gene names: 51893445

Gene position: 2492188-2491067 (Counterclockwise)

Preceding gene: 51893446

Following gene: 51893444

Centisome position: 69.88

GC content: 73.89

Gene sequence:

>1122_bases
GTGCGCATCCTGCACCTGGCCGACCTGCATCTGGGATGGAGGCCGGCCTTCATGGCCCGGGAACAGGCGGAGGAGCGGCG
CCGGCGGCGGGACGGCCTGCTGGCCCGGGCCGTGGACCTCGCCCTGGACCCCGGCCGGCGGATCGGGCTCGTGGTCATCG
CCGGCGACCTGTTCGAGACCCACTGCCCCGAGGAGCCCCTGGTCGCCGCGGCCGTCGCCCAGCTCCGCCGGCTGGAGCAG
GCCGGGATCCCCGTGGTGACGGTCCCGGGCAATCACGACGAGATCACCTATCCCAACTCGGTCTACCAGAGGCGCCGGGA
CGGCTGGCCGGGGCTGCTGGTGACCAACCCGCACCCGGCCCACGTGGCCACCATCGAGGCGCAGGGCGAGACCGTGCACC
TGTACAGCCTGGCCTACACCGGCGGCGTCACCCAGACCCGGCCCGCCATCCGTCAGTTCCCCCGCCTCGACCAGCCGGGC
CTGCACGTGGCGATCTTCCACGGCACCCTCGGCGAGGGGCTGGGCGACCGGTCCCTGCCGCTGGATCCGGACGCCCTCGG
GCGGGCCGGCTACGATTACATCGCCCTGGGCCACATCCACAAGCCGTCCGAGGTGCGGCTGGGCCGCGGACTCGCGGTAT
ACCCCGGCACGGTCGAGGGCAAGGGGTTTGACGACCCTGGCACCCGTCAGTTCACCATCGCCTCCGTGGAGCCGGGGGGC
GTGACGCTGGAGCGGGTCCCTGACCCCGCCGCGCAGAAGGTGGCGGTGCACGACCTGGACGTCTCCCCGCTGCCGGGGGC
CGCCCGGGTGGAGGCGGCCGTGGCGGCCCTGGCGGATCCCGAGGCCATCGTCCGGGTACGGCTCACCGGCACGGCGCCGG
AACTGCTGGACGCCGAGGCCATCGAAGCTGCCTGCGCGCACCGGTTCTTCCACCTGGAGGTGGTGGACGAGACCGACGCG
CTCTCCCCGGCGCTCCTGGACCGCTGGGCGGCGGAGCGGACCATCCTGGGCGAGTTCATCCGGCGCATGCGGAGGCGGAT
GGAAGAGGAGCAGGACGAGGACGAGCGGGCCGTCCTGGAGGAGGCGCTGCGCCGCGGGGTGCAGGCCATGCGGAGGAGGT
GA

Upstream 100 bases:

>100_bases
AGGAATTCGTTGGCCCACCGGCCAATTGGTGCAGCAGACCATCTGGGCGGTCCGGTTGCGGGCCGCCGACACGTTCGCGA
AAGGGGGGCCGCGTCCCGTG

Downstream 100 bases:

>100_bases
GGGCGGTGGCCGGCGTGATCTGGCATTCGGTGTCGCTGACCGGCTTCGGCCCGTACGCCCGCAAGGTGACCTATACCTTC
CCCGCCGGCCTGGGGGTGCT

Product: putative phosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRILHLADLHLGWRPAFMAREQAEERRRRRDGLLARAVDLALDPGRRIGLVVIAGDLFETHCPEEPLVAAAVAQLRRLEQ
AGIPVVTVPGNHDEITYPNSVYQRRRDGWPGLLVTNPHPAHVATIEAQGETVHLYSLAYTGGVTQTRPAIRQFPRLDQPG
LHVAIFHGTLGEGLGDRSLPLDPDALGRAGYDYIALGHIHKPSEVRLGRGLAVYPGTVEGKGFDDPGTRQFTIASVEPGG
VTLERVPDPAAQKVAVHDLDVSPLPGAARVEAAVAALADPEAIVRVRLTGTAPELLDAEAIEAACAHRFFHLEVVDETDA
LSPALLDRWAAERTILGEFIRRMRRRMEEEQDEDERAVLEEALRRGVQAMRRR

Sequences:

>Translated_373_residues
MRILHLADLHLGWRPAFMAREQAEERRRRRDGLLARAVDLALDPGRRIGLVVIAGDLFETHCPEEPLVAAAVAQLRRLEQ
AGIPVVTVPGNHDEITYPNSVYQRRRDGWPGLLVTNPHPAHVATIEAQGETVHLYSLAYTGGVTQTRPAIRQFPRLDQPG
LHVAIFHGTLGEGLGDRSLPLDPDALGRAGYDYIALGHIHKPSEVRLGRGLAVYPGTVEGKGFDDPGTRQFTIASVEPGG
VTLERVPDPAAQKVAVHDLDVSPLPGAARVEAAVAALADPEAIVRVRLTGTAPELLDAEAIEAACAHRFFHLEVVDETDA
LSPALLDRWAAERTILGEFIRRMRRRMEEEQDEDERAVLEEALRRGVQAMRRR
>Mature_373_residues
MRILHLADLHLGWRPAFMAREQAEERRRRRDGLLARAVDLALDPGRRIGLVVIAGDLFETHCPEEPLVAAAVAQLRRLEQ
AGIPVVTVPGNHDEITYPNSVYQRRRDGWPGLLVTNPHPAHVATIEAQGETVHLYSLAYTGGVTQTRPAIRQFPRLDQPG
LHVAIFHGTLGEGLGDRSLPLDPDALGRAGYDYIALGHIHKPSEVRLGRGLAVYPGTVEGKGFDDPGTRQFTIASVEPGG
VTLERVPDPAAQKVAVHDLDVSPLPGAARVEAAVAALADPEAIVRVRLTGTAPELLDAEAIEAACAHRFFHLEVVDETDA
LSPALLDRWAAERTILGEFIRRMRRRMEEEQDEDERAVLEEALRRGVQAMRRR

Specific function: Sbccd Cleaves DNA Hairpin Structures. These Structures Can Inhibit DNA Replication And Are Intermediates In Certain DNA Recombination Reactions. The Complex Acts As A 3'->5' Double Strand Exonuclease That Can Open Hairpins. It Also Has A 5' Single-Strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR014576 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 41017; Mature: 41017

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILHLADLHLGWRPAFMAREQAEERRRRRDGLLARAVDLALDPGRRIGLVVIAGDLFET
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEEEECCHHHH
HCPEEPLVAAAVAQLRRLEQAGIPVVTVPGNHDEITYPNSVYQRRRDGWPGLLVTNPHPA
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCC
HVATIEAQGETVHLYSLAYTGGVTQTRPAIRQFPRLDQPGLHVAIFHGTLGEGLGDRSLP
EEEEEEECCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCC
LDPDALGRAGYDYIALGHIHKPSEVRLGRGLAVYPGTVEGKGFDDPGTRQFTIASVEPGG
CCHHHHCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCC
VTLERVPDPAAQKVAVHDLDVSPLPGAARVEAAVAALADPEAIVRVRLTGTAPELLDAEA
EEEECCCCCHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
IEAACAHRFFHLEVVDETDALSPALLDRWAAERTILGEFIRRMRRRMEEEQDEDERAVLE
HHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EALRRGVQAMRRR
HHHHHHHHHHHCC
>Mature Secondary Structure
MRILHLADLHLGWRPAFMAREQAEERRRRRDGLLARAVDLALDPGRRIGLVVIAGDLFET
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEEEECCHHHH
HCPEEPLVAAAVAQLRRLEQAGIPVVTVPGNHDEITYPNSVYQRRRDGWPGLLVTNPHPA
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCC
HVATIEAQGETVHLYSLAYTGGVTQTRPAIRQFPRLDQPGLHVAIFHGTLGEGLGDRSLP
EEEEEEECCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCC
LDPDALGRAGYDYIALGHIHKPSEVRLGRGLAVYPGTVEGKGFDDPGTRQFTIASVEPGG
CCHHHHCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCC
VTLERVPDPAAQKVAVHDLDVSPLPGAARVEAAVAALADPEAIVRVRLTGTAPELLDAEA
EEEECCCCCHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
IEAACAHRFFHLEVVDETDALSPALLDRWAAERTILGEFIRRMRRRMEEEQDEDERAVLE
HHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EALRRGVQAMRRR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]