Click here to switch to the map view.

The map label for this gene is sorA [H]

Identifier: 51893080

GI number: 51893080

Start: 2083864

End: 2084607

Strand: Reverse

Name: sorA [H]

Synonym: STH1942

Alternate gene names: 51893080

Gene position: 2084607-2083864 (Counterclockwise)

Preceding gene: 51893082

Following gene: 51893079

Centisome position: 58.46

GC content: 65.99

Gene sequence:

>744_bases
TTGACGTATGGCATTGGGATTGCACTGCTCCTGGGAATCATCGCGTACATTGCGGTCGTGATGAATCTGGGTGCCAGCGT
CTTCTGGCACGAGGCGCTCATCGTCGGCGCGGTTACGGGACTCATCGTCGGAGATGTGCAGATGGGCCTCACGATCGGCG
CGACGCTGACCCTCATGTCCCTCGGCATGTGGACTTACGGCGGTGCGACGATCCCCGACTTCATGACCGGCGCCATCCTC
GGCACCGCGTTCGGCGCACTGCCGGGCGTGGGGGTCGAGGGCGGCCTCGCCATCGCGGTGCCGGCGGCGCTGCTCATGAC
CCAGCTGGACGTGCTGGGCCGCGCCACCACGACGCTGTTCATCCACGGCGCCGACAAGGCGGTCGCCGAAGGCAACGTGC
GCGCGGTCACCTGGTGGCACCTGCTGGGCCAGCTGCCCTGGGGCCTCACACGGTTCTTCCCGGTCTTCCTTGCGGTCTGG
CTGGGCGCAGAGCCCGTGCAGAACTTCATCAACTGGATGCCGGACCACGTCATGAACGCCATGCGGGTCACCGGCGCCGT
CCTGCCGGCCCTCGGTTTCGCCCTACTGCTGACCATGATGCCGCTGAAGAAGTACTGGCCGTTCGCCCTGCTGGGCTACG
TCCTGTTCGCTTACCTGAAGGTGCCCATGATCGGCATCGCGCTCACCGCTGTCGCCGTCGGCATCCTCTACCTCAACCTG
AAGGAGGTGCGGGCTCGTGGCTAA

Upstream 100 bases:

>100_bases
ACACACCCGCCGGGCAGCGCCTGGGAAAGGAGGGAAGCGCGGCCTCGGCCCGGCGACGTGTCCATCTGGAGGATCAAACT
AGGACCGGAGGTGTGTTGCG

Downstream 100 bases:

>100_bases
CACGCAGGTAGACCAGAGCCAGGTATTGCCGGAGTACGGCCCGGTAACCCCCGCTGACCTCAGGAAGGCCGCCTGGCGGC
ACAACCTGACGCTCCAGTGG

Product: PTS system fructose/mannose-specific IIC component

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTYGIGIALLLGIIAYIAVVMNLGASVFWHEALIVGAVTGLIVGDVQMGLTIGATLTLMSLGMWTYGGATIPDFMTGAIL
GTAFGALPGVGVEGGLAIAVPAALLMTQLDVLGRATTTLFIHGADKAVAEGNVRAVTWWHLLGQLPWGLTRFFPVFLAVW
LGAEPVQNFINWMPDHVMNAMRVTGAVLPALGFALLLTMMPLKKYWPFALLGYVLFAYLKVPMIGIALTAVAVGILYLNL
KEVRARG

Sequences:

>Translated_247_residues
MTYGIGIALLLGIIAYIAVVMNLGASVFWHEALIVGAVTGLIVGDVQMGLTIGATLTLMSLGMWTYGGATIPDFMTGAIL
GTAFGALPGVGVEGGLAIAVPAALLMTQLDVLGRATTTLFIHGADKAVAEGNVRAVTWWHLLGQLPWGLTRFFPVFLAVW
LGAEPVQNFINWMPDHVMNAMRVTGAVLPALGFALLLTMMPLKKYWPFALLGYVLFAYLKVPMIGIALTAVAVGILYLNL
KEVRARG
>Mature_246_residues
TYGIGIALLLGIIAYIAVVMNLGASVFWHEALIVGAVTGLIVGDVQMGLTIGATLTLMSLGMWTYGGATIPDFMTGAILG
TAFGALPGVGVEGGLAIAVPAALLMTQLDVLGRATTTLFIHGADKAVAEGNVRAVTWWHLLGQLPWGLTRFFPVFLAVWL
GAEPVQNFINWMPDHVMNAMRVTGAVLPALGFALLLTMMPLKKYWPFALLGYVLFAYLKVPMIGIALTAVAVGILYLNLK
EVRARG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=239, Percent_Identity=28.8702928870293, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789528, Length=221, Percent_Identity=29.8642533936652, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 26214; Mature: 26083

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCC
>Mature Secondary Structure 
TYGIGIALLLGIIAYIAVVMNLGASVFWHEALIVGAVTGLIVGDVQMGLTIGATLTLMS
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMWTYGGATIPDFMTGAILGTAFGALPGVGVEGGLAIAVPAALLMTQLDVLGRATTTLF
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
IHGADKAVAEGNVRAVTWWHLLGQLPWGLTRFFPVFLAVWLGAEPVQNFINWMPDHVMNA
EECCCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHH
MRVTGAVLPALGFALLLTMMPLKKYWPFALLGYVLFAYLKVPMIGIALTAVAVGILYLNL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEVRARG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]