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The map label for this gene is manX [H]

Identifier: 51893078

GI number: 51893078

Start: 2082553

End: 2082951

Strand: Reverse

Name: manX [H]

Synonym: STH1940

Alternate gene names: 51893078

Gene position: 2082951-2082553 (Counterclockwise)

Preceding gene: 51893079

Following gene: 51893077

Centisome position: 58.41

GC content: 71.68

Gene sequence:

>399_bases
GTGATCGGCATCGTGCTGATCAGCCATGGTCCCTTGGCATCGGGCCTTCTGCAGGCCGCCGAGATGATCGCGGGGGAGCA
GTCCCAGGTGGCCGTCTTGGAGCTGCAGCCGGCCCAGGAGATGGACCAGTTCCGCGAGGCGATGGAGCAGGCGGTGGCCC
GGGTGGATTCCGGCGACGGCGTGCTGATCGTGGCGGACCTGTTCGGCGGCAGCCCCGCCAACACGTCCGCGTACCTGCTG
CGCCCCGGCGTGGAGGTGGTCTGCGGCGCCAACCTGCCGATGCTGCTGGAGGTCCTGACCCTGCGCGACGGCCAGACGCT
TTCGGAGCTGGCGCAGACCGCCGTGCAGGCGGGCGCCTCCGGTGCCCTGCGCCTGGCCGACGTGCTCGGCCGGGGTTGA

Upstream 100 bases:

>100_bases
TCGCCTTCGCCTGCAGCTATCTGGGCATCCTGTAATGCACGGCACCGGGGGGGCGGGGACCTGACCCCGCCCCCCGCCGC
CACGTAAGGGGGTGAGACCG

Downstream 100 bases:

>100_bases
TCAGATCTCACGATCGGGAGGAGAGAGACGTATGCCCGTGGTCCACATGCGCATCGACAACCGCCTGATCCACGGTCAGG
TCACGGTCGCGTGGGCGAGC

Product: PTS system mannose/fructose-specific IIA component

Products: NA

Alternate protein names: EIIAB-Man; Mannose-specific phosphotransferase enzyme IIA component; EIII-Man; PTS system mannose-specific EIIA component; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MIGIVLISHGPLASGLLQAAEMIAGEQSQVAVLELQPAQEMDQFREAMEQAVARVDSGDGVLIVADLFGGSPANTSAYLL
RPGVEVVCGANLPMLLEVLTLRDGQTLSELAQTAVQAGASGALRLADVLGRG

Sequences:

>Translated_132_residues
MIGIVLISHGPLASGLLQAAEMIAGEQSQVAVLELQPAQEMDQFREAMEQAVARVDSGDGVLIVADLFGGSPANTSAYLL
RPGVEVVCGANLPMLLEVLTLRDGQTLSELAQTAVQAGASGALRLADVLGRG
>Mature_132_residues
MIGIVLISHGPLASGLLQAAEMIAGEQSQVAVLELQPAQEMDQFREAMEQAVARVDSGDGVLIVADLFGGSPANTSAYLL
RPGVEVVCGANLPMLLEVLTLRDGQTLSELAQTAVQAGASGALRLADVLGRG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788120, Length=123, Percent_Identity=36.5853658536585, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004701
- InterPro:   IPR013789
- InterPro:   IPR004720
- InterPro:   IPR018455 [H]

Pfam domain/function: PF03610 EIIA-man; PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 13582; Mature: 13582

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIVLISHGPLASGLLQAAEMIAGEQSQVAVLELQPAQEMDQFREAMEQAVARVDSGDG
CEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
VLIVADLFGGSPANTSAYLLRPGVEVVCGANLPMLLEVLTLRDGQTLSELAQTAVQAGAS
EEEEEECCCCCCCCCCEEEECCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC
GALRLADVLGRG
CHHHHHHHHCCC
>Mature Secondary Structure
MIGIVLISHGPLASGLLQAAEMIAGEQSQVAVLELQPAQEMDQFREAMEQAVARVDSGDG
CEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
VLIVADLFGGSPANTSAYLLRPGVEVVCGANLPMLLEVLTLRDGQTLSELAQTAVQAGAS
EEEEEECCCCCCCCCCEEEECCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC
GALRLADVLGRG
CHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]