Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 51892411

GI number: 51892411

Start: 1409232

End: 1410851

Strand: Reverse

Name: xylB [H]

Synonym: STH1273

Alternate gene names: 51892411

Gene position: 1410851-1409232 (Counterclockwise)

Preceding gene: 51892412

Following gene: 51892410

Centisome position: 39.56

GC content: 74.14

Gene sequence:

>1620_bases
ATGGCCCAGCAGTACGTCCTGGCGCTGGATCTGGGCACGTCGGCCCTGAAGGCGGCCCTGGTCTCCTTCACCGGCGCCGT
CGCCGGCCTGGAGACCGAGCCCGTCCCGCTCACGGTGCTGCCCGGCGGCGGGGCCGAGCAGAACCCCGAAGACTGGTGGA
ACGCCCTGGTCACCGCCACCCGCAGGCTCATGGCCCGGGGCATCGCGGGGCCGGACCGGGTGGCCGCCGTCTGCTGCACG
GCCCAGTGGTCCGCCACCGTGGCCGTCGACCGCGCCGGCCGCCCGCTGATGCCCGCCATCAGCTGGATGGACACCCGCGG
CGCGCCGGACGTCGCCCGGCTGACCGGCGGGCCGGTCTCGGTGGCCGGCTACGGCGTGGACAAGCTGTGGCGCTGGATCC
GCCGGACCGGGGGCATCCCCGGAAAGGCGGGCAAGGACTCGCTGGCCCACATCCTCTACATCCGCCGGGCGCACCCCTGG
GTGTACGAGGCCGCGCACAAGTTCCTGGAGCCGAAGGACTACCTGAACCTCCGCCTCACCGGCGAGTTCGCCTCGACCTA
CGAGGCCATCACGCTGCACTGGGTCACCGACAACCGGGATCCCTACCACATCCGCTACGACCCCGACCTGCTGGCCGCCG
CGGGCCTGGAGCGGGCCCAGCTGCCGGACCTGCTCCCCGCGACGGCGGTCCTCGGCCGGCTGCGCCCCGCCGCGGCGGAG
GAGCTGGGGCTGCGGCCGGAGACCCACGTGATCGCCGGCACGCCGGACATCCACGCGGCCGCCATCGGCTCCGGCGGCAC
GCGCGACCTGGATCCCCACCTGTACGTGGGCACCTCCTCCTGGCTGTCGGCGCACGTGCCCTACCTGAAGACCGACCTGC
TGCACAACATGGCCTCCATCCCGGCGGCCATCCCCGGCCGCTACCTGGTGGCCAACGAGCAGGAGACCGCCGGCGCGTGC
CTGCTCCACCTGCGGGACCTGCTCGCAGACCCCTCCGGCCGGACGCCCCGGACCCAGACCCTTTCGGATGGGCGCGGGGC
CTCCACGGACGAGGAGGCGCCCGACGAGATGACGCGGCTGATCAACCTCGCTGCCGGGGTTCCGGCAGGCAGCGACGGGC
TCCTCTTCACCCCCTGGCTCGCGGGCGAACGGACGCCCGTCGAGGACCCCTGGGTGCGGGGCGGGTTCCACAACCTCACG
CTGCGCACCACCCGCGGCCACCTGGTGCGGGCCGTGCTGGAGGGGGTCGCCCTAAACGCCCGGTGGCTGGCCGAGGCGGT
GGACCGGTTCGTCGGCCGGCGGCTGGAGCCCGTCCGGCTGATCGGCGGCGGCGCCCGTTCGGAGCTCTGGTGCCAGATCT
ACGCCGACGTCCTGGACCGGGCGGTCCACCAGATGGAACGGCCCCTGGAGGCGAGTGCGCGCGGCGCCGGCCTCCTCGCG
CTGGTAGGCCTGGGCGAACTGAACTTCGCCGACGTGCCGGAGCTGGTCGCCGCCGCCCGCACCTTCGAACCCACCCCCGC
CCACCGCCGGATCTACGCCGAGCTGTCCGCCGCGTTCCGGGAACTCTACCGGCGACAACGGGGCGTCTACGCCCGTCTAA
ACAGGCGGACGGCCCGGTGA

Upstream 100 bases:

>100_bases
GGATGGCCCCGGTCTACGGCATGGCCGCCGCCGCGCCGCCGGAGCTGGTCCGGCAGGTGCTCACCGGCTTCATCGACCTG
CTGTACGAGGTGTGACCGCC

Downstream 100 bases:

>100_bases
CGAGGACCACCGGGCCGAAGACATGCATAAGGGGAGATCCGTATGAGACAGACCCTGCGCTGGGCGGCCGTAGACTCGAC
GGAAACCGAGGAACTGGTGC

Product: xylulose kinase

Products: ADP; D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MAQQYVLALDLGTSALKAALVSFTGAVAGLETEPVPLTVLPGGGAEQNPEDWWNALVTATRRLMARGIAGPDRVAAVCCT
AQWSATVAVDRAGRPLMPAISWMDTRGAPDVARLTGGPVSVAGYGVDKLWRWIRRTGGIPGKAGKDSLAHILYIRRAHPW
VYEAAHKFLEPKDYLNLRLTGEFASTYEAITLHWVTDNRDPYHIRYDPDLLAAAGLERAQLPDLLPATAVLGRLRPAAAE
ELGLRPETHVIAGTPDIHAAAIGSGGTRDLDPHLYVGTSSWLSAHVPYLKTDLLHNMASIPAAIPGRYLVANEQETAGAC
LLHLRDLLADPSGRTPRTQTLSDGRGASTDEEAPDEMTRLINLAAGVPAGSDGLLFTPWLAGERTPVEDPWVRGGFHNLT
LRTTRGHLVRAVLEGVALNARWLAEAVDRFVGRRLEPVRLIGGGARSELWCQIYADVLDRAVHQMERPLEASARGAGLLA
LVGLGELNFADVPELVAAARTFEPTPAHRRIYAELSAAFRELYRRQRGVYARLNRRTAR

Sequences:

>Translated_539_residues
MAQQYVLALDLGTSALKAALVSFTGAVAGLETEPVPLTVLPGGGAEQNPEDWWNALVTATRRLMARGIAGPDRVAAVCCT
AQWSATVAVDRAGRPLMPAISWMDTRGAPDVARLTGGPVSVAGYGVDKLWRWIRRTGGIPGKAGKDSLAHILYIRRAHPW
VYEAAHKFLEPKDYLNLRLTGEFASTYEAITLHWVTDNRDPYHIRYDPDLLAAAGLERAQLPDLLPATAVLGRLRPAAAE
ELGLRPETHVIAGTPDIHAAAIGSGGTRDLDPHLYVGTSSWLSAHVPYLKTDLLHNMASIPAAIPGRYLVANEQETAGAC
LLHLRDLLADPSGRTPRTQTLSDGRGASTDEEAPDEMTRLINLAAGVPAGSDGLLFTPWLAGERTPVEDPWVRGGFHNLT
LRTTRGHLVRAVLEGVALNARWLAEAVDRFVGRRLEPVRLIGGGARSELWCQIYADVLDRAVHQMERPLEASARGAGLLA
LVGLGELNFADVPELVAAARTFEPTPAHRRIYAELSAAFRELYRRQRGVYARLNRRTAR
>Mature_538_residues
AQQYVLALDLGTSALKAALVSFTGAVAGLETEPVPLTVLPGGGAEQNPEDWWNALVTATRRLMARGIAGPDRVAAVCCTA
QWSATVAVDRAGRPLMPAISWMDTRGAPDVARLTGGPVSVAGYGVDKLWRWIRRTGGIPGKAGKDSLAHILYIRRAHPWV
YEAAHKFLEPKDYLNLRLTGEFASTYEAITLHWVTDNRDPYHIRYDPDLLAAAGLERAQLPDLLPATAVLGRLRPAAAEE
LGLRPETHVIAGTPDIHAAAIGSGGTRDLDPHLYVGTSSWLSAHVPYLKTDLLHNMASIPAAIPGRYLVANEQETAGACL
LHLRDLLADPSGRTPRTQTLSDGRGASTDEEAPDEMTRLINLAAGVPAGSDGLLFTPWLAGERTPVEDPWVRGGFHNLTL
RTTRGHLVRAVLEGVALNARWLAEAVDRFVGRRLEPVRLIGGGARSELWCQIYADVLDRAVHQMERPLEASARGAGLLAL
VGLGELNFADVPELVAAARTFEPTPAHRRIYAELSAAFRELYRRQRGVYARLNRRTAR

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789987, Length=534, Percent_Identity=27.3408239700375, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1789168, Length=497, Percent_Identity=26.3581488933602, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790005, Length=545, Percent_Identity=24.4036697247706, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787789, Length=546, Percent_Identity=23.992673992674, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790361, Length=521, Percent_Identity=23.2245681381958, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71986147, Length=177, Percent_Identity=29.3785310734463, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71986140, Length=177, Percent_Identity=29.3785310734463, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357867, Length=534, Percent_Identity=23.9700374531835, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656367, Length=528, Percent_Identity=23.8636363636364, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656372, Length=326, Percent_Identity=26.0736196319018, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24657106, Length=493, Percent_Identity=21.9066937119675, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24657102, Length=493, Percent_Identity=21.9066937119675, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: 2.7.1.17

Molecular weight: Translated: 58485; Mature: 58354

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQQYVLALDLGTSALKAALVSFTGAVAGLETEPVPLTVLPGGGAEQNPEDWWNALVTAT
CCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RRLMARGIAGPDRVAAVCCTAQWSATVAVDRAGRPLMPAISWMDTRGAPDVARLTGGPVS
HHHHHHCCCCHHHHEEEEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCHHHHCCCCEE
VAGYGVDKLWRWIRRTGGIPGKAGKDSLAHILYIRRAHPWVYEAAHKFLEPKDYLNLRLT
EECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHEEEEEE
GEFASTYEAITLHWVTDNRDPYHIRYDPDLLAAAGLERAQLPDLLPATAVLGRLRPAAAE
CCHHCCEEEEEEEEEECCCCCEEEEECCHHHHHCCCCHHCCCCHHHHHHHHHHCCCHHHH
ELGLRPETHVIAGTPDIHAAAIGSGGTRDLDPHLYVGTSSWLSAHVPYLKTDLLHNMASI
HHCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEECCCHHHHHCCCHHHHHHHHHHHHC
PAAIPGRYLVANEQETAGACLLHLRDLLADPSGRTPRTQTLSDGRGASTDEEAPDEMTRL
CCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
INLAAGVPAGSDGLLFTPWLAGERTPVEDPWVRGGFHNLTLRTTRGHLVRAVLEGVALNA
HHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCH
RWLAEAVDRFVGRRLEPVRLIGGGARSELWCQIYADVLDRAVHQMERPLEASARGAGLLA
HHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEE
LVGLGELNFADVPELVAAARTFEPTPAHRRIYAELSAAFRELYRRQRGVYARLNRRTAR
EEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure 
AQQYVLALDLGTSALKAALVSFTGAVAGLETEPVPLTVLPGGGAEQNPEDWWNALVTAT
CCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RRLMARGIAGPDRVAAVCCTAQWSATVAVDRAGRPLMPAISWMDTRGAPDVARLTGGPVS
HHHHHHCCCCHHHHEEEEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCHHHHCCCCEE
VAGYGVDKLWRWIRRTGGIPGKAGKDSLAHILYIRRAHPWVYEAAHKFLEPKDYLNLRLT
EECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHEEEEEE
GEFASTYEAITLHWVTDNRDPYHIRYDPDLLAAAGLERAQLPDLLPATAVLGRLRPAAAE
CCHHCCEEEEEEEEEECCCCCEEEEECCHHHHHCCCCHHCCCCHHHHHHHHHHCCCHHHH
ELGLRPETHVIAGTPDIHAAAIGSGGTRDLDPHLYVGTSSWLSAHVPYLKTDLLHNMASI
HHCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEECCCHHHHHCCCHHHHHHHHHHHHC
PAAIPGRYLVANEQETAGACLLHLRDLLADPSGRTPRTQTLSDGRGASTDEEAPDEMTRL
CCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
INLAAGVPAGSDGLLFTPWLAGERTPVEDPWVRGGFHNLTLRTTRGHLVRAVLEGVALNA
HHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCH
RWLAEAVDRFVGRRLEPVRLIGGGARSELWCQIYADVLDRAVHQMERPLEASARGAGLLA
HHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEE
LVGLGELNFADVPELVAAARTFEPTPAHRRIYAELSAAFRELYRRQRGVYARLNRRTAR
EEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-xylulose

Specific reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA