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The map label for this gene is udk [H]

Identifier: 51892184

GI number: 51892184

Start: 1163762

End: 1164397

Strand: Reverse

Name: udk [H]

Synonym: STH1046

Alternate gene names: 51892184

Gene position: 1164397-1163762 (Counterclockwise)

Preceding gene: 51892195

Following gene: 51892183

Centisome position: 32.65

GC content: 65.88

Gene sequence:

>636_bases
ATGCCAGCCCCGAGGGCAGTGATCGCGATCGCCGGGGGCACGGGCTCCGGGAAGACCACCATCGCCAACTACATCTCGGC
CGCGTTCCCGGACGACGTGGCGCTGCTGCCCCACGATGCCTACTACAAGGACAACCGGAACCTCACCTACGAAGAGCGGA
GCCAGCTCAACTACGACCACCCCGACGCCTTCGACAACGACCTGTTCATCGCCCACCTGAAGGCACTGAAGGCTGGCCAG
GCGGTGGAGCGGCCGGTGTACAACTTCTCGACCCACCTGCGGGAGCACCAGACCCTGCGGGTGGAGCCGGCGGCGATCAT
CGTCGTGGAAGGCGTACTGGTGCTGGCGCATCCGGAGCTGCGCGCCCTGTACGACCTCAGCGTGTTCGTGGACACCGACG
CCGACGTGCGCATCCTGCGCCGGATCGTGCGTGACATCCACGAGCGCGGGCGCACCCTGGATTCGGTGATCAACCAGTAC
CTGTCCACCGTCAAGCCCATGCATGAGGCCTTCGTCGAGCCGAGCAAGCGGTACGCCAACGTCATCATTCCCGAGGGGGC
CCACAACAAACCGGGGCTCGAGGTCCTGATCGCGCAGGTCCGCCACCTGATCGCCCAGCATGAACCCTCAGCCTGA

Upstream 100 bases:

>100_bases
CCGCGCGCAGCCCTTGCGCACGTCCACCCCCTGGGGGATAATCGAACGGGGACTTCTGGACTCTGCAAGCGCCAGCGCAT
GTTCTAAGGAGGGTATCTCT

Downstream 100 bases:

>100_bases
GTGGCTTTTCACGCCTGCGCCCCTATGGTACACTTAAGCTGTCGTGTGCCCAAAGTTTTGGTGCCTGCCACGGGCACCGA
TTCGGGGGTGAGAATGCATG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MPAPRAVIAIAGGTGSGKTTIANYISAAFPDDVALLPHDAYYKDNRNLTYEERSQLNYDHPDAFDNDLFIAHLKALKAGQ
AVERPVYNFSTHLREHQTLRVEPAAIIVVEGVLVLAHPELRALYDLSVFVDTDADVRILRRIVRDIHERGRTLDSVINQY
LSTVKPMHEAFVEPSKRYANVIIPEGAHNKPGLEVLIAQVRHLIAQHEPSA

Sequences:

>Translated_211_residues
MPAPRAVIAIAGGTGSGKTTIANYISAAFPDDVALLPHDAYYKDNRNLTYEERSQLNYDHPDAFDNDLFIAHLKALKAGQ
AVERPVYNFSTHLREHQTLRVEPAAIIVVEGVLVLAHPELRALYDLSVFVDTDADVRILRRIVRDIHERGRTLDSVINQY
LSTVKPMHEAFVEPSKRYANVIIPEGAHNKPGLEVLIAQVRHLIAQHEPSA
>Mature_210_residues
PAPRAVIAIAGGTGSGKTTIANYISAAFPDDVALLPHDAYYKDNRNLTYEERSQLNYDHPDAFDNDLFIAHLKALKAGQA
VERPVYNFSTHLREHQTLRVEPAAIIVVEGVLVLAHPELRALYDLSVFVDTDADVRILRRIVRDIHERGRTLDSVINQYL
STVKPMHEAFVEPSKRYANVIIPEGAHNKPGLEVLIAQVRHLIAQHEPSA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=211, Percent_Identity=39.3364928909953, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI57863312, Length=209, Percent_Identity=39.7129186602871, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI301129207, Length=209, Percent_Identity=39.7129186602871, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI13899253, Length=224, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI209863022, Length=161, Percent_Identity=40.3726708074534, Blast_Score=111, Evalue=6e-25,
Organism=Escherichia coli, GI87082034, Length=202, Percent_Identity=43.5643564356436, Blast_Score=194, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17539892, Length=201, Percent_Identity=38.8059701492537, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17539894, Length=201, Percent_Identity=38.8059701492537, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71981181, Length=197, Percent_Identity=36.0406091370558, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6324339, Length=150, Percent_Identity=34.6666666666667, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45550449, Length=204, Percent_Identity=43.6274509803922, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28573516, Length=204, Percent_Identity=43.6274509803922, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28573514, Length=204, Percent_Identity=43.6274509803922, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28573512, Length=204, Percent_Identity=43.6274509803922, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI221458995, Length=212, Percent_Identity=37.7358490566038, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24649624, Length=213, Percent_Identity=37.5586854460094, Blast_Score=157, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23557; Mature: 23426

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00227 TUBULIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPRAVIAIAGGTGSGKTTIANYISAAFPDDVALLPHDAYYKDNRNLTYEERSQLNYDH
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCC
PDAFDNDLFIAHLKALKAGQAVERPVYNFSTHLREHQTLRVEPAAIIVVEGVLVLAHPEL
CCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCEEEECCEEEEEEECEEEEECCHH
RALYDLSVFVDTDADVRILRRIVRDIHERGRTLDSVINQYLSTVKPMHEAFVEPSKRYAN
HHHEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCE
VIIPEGAHNKPGLEVLIAQVRHLIAQHEPSA
EEECCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PAPRAVIAIAGGTGSGKTTIANYISAAFPDDVALLPHDAYYKDNRNLTYEERSQLNYDH
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCC
PDAFDNDLFIAHLKALKAGQAVERPVYNFSTHLREHQTLRVEPAAIIVVEGVLVLAHPEL
CCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCEEEECCEEEEEEECEEEEECCHH
RALYDLSVFVDTDADVRILRRIVRDIHERGRTLDSVINQYLSTVKPMHEAFVEPSKRYAN
HHHEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCE
VIIPEGAHNKPGLEVLIAQVRHLIAQHEPSA
EEECCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]