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The map label for this gene is appC [H]

Identifier: 51892174

GI number: 51892174

Start: 1153426

End: 1154349

Strand: Reverse

Name: appC [H]

Synonym: STH1036

Alternate gene names: 51892174

Gene position: 1154349-1153426 (Counterclockwise)

Preceding gene: 51892175

Following gene: 51892173

Centisome position: 32.37

GC content: 66.67

Gene sequence:

>924_bases
GTGGCGATCTCCCGTCCTACACCGGACCCGATTCCGACCCAGTTCGACGGCCTGACGGCGCAGGAGACCTCGTACGCCCG
GCTGGTGCTGCGGCGGTTCCTCCGGAACCGCATGGCCGTCGCCGGGGCGACGATCCTCCTCATCCTGATCCTCATCTCCG
CCTTCGCGCCGGTCATCACCCAGGCCACCCTCGGCTGGGGACGCGACGAAATCGACATCCAGTACATCCGGGCAGCGCCC
TCCGCCCGCCACCCGCTCGGCACCGACAGCGCCGGTCGAGACAACCTCACCCGCCTGCTGTACGGCGGCCGGGTGTCGCT
GTCGATCGCCTTGGGATCCGTCATCGTGTACATGGTCCTGGGCATCGTCATCGGCTCGGTCGCGGGCTACTTCGGCGGCT
GGATCGACAACGTGCTCATGCGGCTGGTGGACGTGATCCAGTCCTTCCCGTTCCTGATGTTCGCCCTGACCATCGTCGCG
ATCCGAGGCCCGTCGGTTTCCAATCTGGTGTTCGCGATCGTCTTCCTTAGCTGGCCAGTGCCGGCCCGCCTCGTGCGGGG
AGAGTTCCTCTCCCTGCGGGAGAGGGATTTCATCGAAGCGGCCCGGGCCGCGGGAGTCGGCACGTTCCGCATGATCGTGC
GCCACCTCCTGCCCAACGCCATGGCGCCGCTGATCGTGAACGCCACCCTGGAAGTCGCGGGGATCATCCTCGCGGAGGCG
GGGCTCAGCTACCTGGGGTTCGGCGTGAACCAGCCAGTCCCCACGTGGGGGAACATGCTGAGTGAGGCAAACAACATGGC
CGTGCTGCAGACCAGACCGTGGACGTGGATCCCGCCGGGCCTGATGATCTTCCTGACGGTGCTTTCCATCAACTTCATCG
GGGACGGGCTGCGCGATGCGCTCGACCCGCGCCTGAAACAGTAG

Upstream 100 bases:

>100_bases
CATGTTCTTCGCCCTGCTGGTCATCCTGGGTAACCTCATCGCCGACATCCTCTATGCCGTCGCTGACCCCCGCATCCGGT
ATGCGTAAGGAGGTACAGCC

Downstream 100 bases:

>100_bases
CGGACAGAGGGGGATACCTGTGAGGAGACGCAAGATCCTGATCTGGGCAGCAGCGGCGCTGCTGGCCGTGCTGGTGGCCG
GCTGCGGCAAGTACGCGGAC

Product: oligopeptide ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAISRPTPDPIPTQFDGLTAQETSYARLVLRRFLRNRMAVAGATILLILILISAFAPVITQATLGWGRDEIDIQYIRAAP
SARHPLGTDSAGRDNLTRLLYGGRVSLSIALGSVIVYMVLGIVIGSVAGYFGGWIDNVLMRLVDVIQSFPFLMFALTIVA
IRGPSVSNLVFAIVFLSWPVPARLVRGEFLSLRERDFIEAARAAGVGTFRMIVRHLLPNAMAPLIVNATLEVAGIILAEA
GLSYLGFGVNQPVPTWGNMLSEANNMAVLQTRPWTWIPPGLMIFLTVLSINFIGDGLRDALDPRLKQ

Sequences:

>Translated_307_residues
MAISRPTPDPIPTQFDGLTAQETSYARLVLRRFLRNRMAVAGATILLILILISAFAPVITQATLGWGRDEIDIQYIRAAP
SARHPLGTDSAGRDNLTRLLYGGRVSLSIALGSVIVYMVLGIVIGSVAGYFGGWIDNVLMRLVDVIQSFPFLMFALTIVA
IRGPSVSNLVFAIVFLSWPVPARLVRGEFLSLRERDFIEAARAAGVGTFRMIVRHLLPNAMAPLIVNATLEVAGIILAEA
GLSYLGFGVNQPVPTWGNMLSEANNMAVLQTRPWTWIPPGLMIFLTVLSINFIGDGLRDALDPRLKQ
>Mature_306_residues
AISRPTPDPIPTQFDGLTAQETSYARLVLRRFLRNRMAVAGATILLILILISAFAPVITQATLGWGRDEIDIQYIRAAPS
ARHPLGTDSAGRDNLTRLLYGGRVSLSIALGSVIVYMVLGIVIGSVAGYFGGWIDNVLMRLVDVIQSFPFLMFALTIVAI
RGPSVSNLVFAIVFLSWPVPARLVRGEFLSLRERDFIEAARAAGVGTFRMIVRHLLPNAMAPLIVNATLEVAGIILAEAG
LSYLGFGVNQPVPTWGNMLSEANNMAVLQTRPWTWIPPGLMIFLTVLSINFIGDGLRDALDPRLKQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=38.768115942029, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1787498, Length=306, Percent_Identity=37.9084967320261, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789964, Length=227, Percent_Identity=46.6960352422907, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1789889, Length=246, Percent_Identity=37.8048780487805, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787760, Length=267, Percent_Identity=34.0823970037453, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=34.2222222222222, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787549, Length=285, Percent_Identity=31.2280701754386, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33453; Mature: 33322

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISRPTPDPIPTQFDGLTAQETSYARLVLRRFLRNRMAVAGATILLILILISAFAPVIT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QATLGWGRDEIDIQYIRAAPSARHPLGTDSAGRDNLTRLLYGGRVSLSIALGSVIVYMVL
HHHHCCCCCCCCHHEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHH
GIVIGSVAGYFGGWIDNVLMRLVDVIQSFPFLMFALTIVAIRGPSVSNLVFAIVFLSWPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
PARLVRGEFLSLRERDFIEAARAAGVGTFRMIVRHLLPNAMAPLIVNATLEVAGIILAEA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GLSYLGFGVNQPVPTWGNMLSEANNMAVLQTRPWTWIPPGLMIFLTVLSINFIGDGLRDA
CHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHH
LDPRLKQ
CCCCCCC
>Mature Secondary Structure 
AISRPTPDPIPTQFDGLTAQETSYARLVLRRFLRNRMAVAGATILLILILISAFAPVIT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]