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The map label for this gene is 51891952

Identifier: 51891952

GI number: 51891952

Start: 914282

End: 915037

Strand: Reverse

Name: 51891952

Synonym: STH814

Alternate gene names: NA

Gene position: 915037-914282 (Counterclockwise)

Preceding gene: 51891953

Following gene: 51891948

Centisome position: 25.66

GC content: 74.21

Gene sequence:

>756_bases
ATGGCCGCCGGGGTAGGTTCACCTGGCGCTGGGCACCCCGGGCTCCGGCACCCCGGGACCGGGGCTCCCGAGACCGCGTA
TTCCGGGACCGGTGACTTCGACCGGCTGATCCTGCACGAGACGCCCTACGGGAAGGTGGAACAGCGGGGCCCCGTGCTCA
TGCGGACGGCGGAGGCCGACCCCCGGGCCCTGATCTACGCAGCCAAGGCGGCGGGCGCGTCCGCCGTTCTGGCCGCGGCG
CGGGTCGAACCGGTCAGCCCCCTCCTGGAGCCGGGCGACCTGGTCGTCCCGGTGGACGTGATCGACCTCACCCGCCTGCT
CCCCCCGACCTTCTTCGTGGGGAAGGGCTACGGGTTCATCCGGCTCGACCCGCCGTTCTGCCCGGAGCTGTCGGCGGCCT
TGTATGCCGCGGGGCGCGAAAAGACCCCCCGGGCGTTCCGGGGGGCGACGTACGTGGGGCTGGACGGATCCCGGGAGGCG
ACGCCGGCCGAGCGGCGGATGTACCGCGCCTGGGGCGCGGACGTCGTCGGTTCCGGGCTGGTGCCGGAGGCGTTTCTCGC
CCGGGAGCTGGAGCTGTGCTACGCCGCGCTGACGGTGGTCAGGGAGGCGCAGGCAGACGTACTGGCTGTTCTGGAGCGGG
CCGCGCAGCTGGCCCCGGTCCGGCGAAGCTGCAGCTGCGGGCGGGCGATGGCCGGCGCCCGGGCGCAGGGGCTGATTGGC
GAGGACTGGCGGGAGTGGGTGCGGGGCAACATGTGA

Upstream 100 bases:

>100_bases
GGGCCGGAGGTGGGACAGCTAATGTTCCGGATCATGCTGCGGCTGCTGGAGGAGGAGGCGAATGCATATGGGTGAGGTGC
TGTTCATCCTGCCGGAGGCG

Downstream 100 bases:

>100_bases
CAGCTGATAGCAGTAGCACTACGGCATGGGAACGTCGCTAGTTCTTGGGGAACCAGAACTATCACCGATAGACAACCCAC
TTATCGCCACGCTTCGTAAC

Product: methylthioadenosine phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAAGVGSPGAGHPGLRHPGTGAPETAYSGTGDFDRLILHETPYGKVEQRGPVLMRTAEADPRALIYAAKAAGASAVLAAA
RVEPVSPLLEPGDLVVPVDVIDLTRLLPPTFFVGKGYGFIRLDPPFCPELSAALYAAGREKTPRAFRGATYVGLDGSREA
TPAERRMYRAWGADVVGSGLVPEAFLARELELCYAALTVVREAQADVLAVLERAAQLAPVRRSCSCGRAMAGARAQGLIG
EDWREWVRGNM

Sequences:

>Translated_251_residues
MAAGVGSPGAGHPGLRHPGTGAPETAYSGTGDFDRLILHETPYGKVEQRGPVLMRTAEADPRALIYAAKAAGASAVLAAA
RVEPVSPLLEPGDLVVPVDVIDLTRLLPPTFFVGKGYGFIRLDPPFCPELSAALYAAGREKTPRAFRGATYVGLDGSREA
TPAERRMYRAWGADVVGSGLVPEAFLARELELCYAALTVVREAQADVLAVLERAAQLAPVRRSCSCGRAMAGARAQGLIG
EDWREWVRGNM
>Mature_250_residues
AAGVGSPGAGHPGLRHPGTGAPETAYSGTGDFDRLILHETPYGKVEQRGPVLMRTAEADPRALIYAAKAAGASAVLAAAR
VEPVSPLLEPGDLVVPVDVIDLTRLLPPTFFVGKGYGFIRLDPPFCPELSAALYAAGREKTPRAFRGATYVGLDGSREAT
PAERRMYRAWGADVVGSGLVPEAFLARELELCYAALTVVREAQADVLAVLERAAQLAPVRRSCSCGRAMAGARAQGLIGE
DWREWVRGNM

Specific function: Unknown

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=146, Percent_Identity=31.5068493150685, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71980569, Length=146, Percent_Identity=28.7671232876712, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323045, Length=155, Percent_Identity=29.6774193548387, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221459247, Length=154, Percent_Identity=32.4675324675325, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20130079, Length=148, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: NA

Molecular weight: Translated: 26568; Mature: 26436

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGVGSPGAGHPGLRHPGTGAPETAYSGTGDFDRLILHETPYGKVEQRGPVLMRTAEAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCC
PRALIYAAKAAGASAVLAAARVEPVSPLLEPGDLVVPVDVIDLTRLLPPTFFVGKGYGFI
CCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEECCEEEE
RLDPPFCPELSAALYAAGREKTPRAFRGATYVGLDGSREATPAERRMYRAWGADVVGSGL
EECCCCCCHHHHHHHHCCCCCCCHHHCCCEEEECCCCCCCCHHHHHHHHHHCCHHHCCCC
VPEAFLARELELCYAALTVVREAQADVLAVLERAAQLAPVRRSCSCGRAMAGARAQGLIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
EDWREWVRGNM
HHHHHHHCCCC
>Mature Secondary Structure 
AAGVGSPGAGHPGLRHPGTGAPETAYSGTGDFDRLILHETPYGKVEQRGPVLMRTAEAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCC
PRALIYAAKAAGASAVLAAARVEPVSPLLEPGDLVVPVDVIDLTRLLPPTFFVGKGYGFI
CCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEECCEEEE
RLDPPFCPELSAALYAAGREKTPRAFRGATYVGLDGSREATPAERRMYRAWGADVVGSGL
EECCCCCCHHHHHHHHCCCCCCCHHHCCCEEEECCCCCCCCHHHHHHHHHHCCHHHCCCC
VPEAFLARELELCYAALTVVREAQADVLAVLERAAQLAPVRRSCSCGRAMAGARAQGLIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
EDWREWVRGNM
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]