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The map label for this gene is asnC [H]

Identifier: 51598364

GI number: 51598364

Start: 98636

End: 100024

Strand: Direct

Name: asnC [H]

Synonym: BG0102

Alternate gene names: 51598364

Gene position: 98636-100024 (Clockwise)

Preceding gene: 51598349

Following gene: 51598365

Centisome position: 10.91

GC content: 30.74

Gene sequence:

>1389_bases
ATGTTTTCAAGCATTAAAGATATTTTAGAAAATCCAATTTTAAACAGCAATGTTACAATAAACGGCTGGATTAGAACTAA
GAGAAGTAATGGTAAGATTGGATTTATAGAAATTAATGATGGCTCAACGCTTAAAGGAATTCAAGCTGTCATAAATGAAG
AAGAAAATCAATTTACTGAAAAAGATCTGAAAAAACTAACAACAGGGGCAAGTATATCGTTAACGGGCCTATTAGTGGAA
AGTCCTGCAAAAGGACAAAATTATGAAATAAAAATATATAGTTTTAATGTAATCGGAGAAGCAGATTCAAAAACTTACCC
ATTGCAAAAAAAGAGACATACTTTTGAATTCTTAAGAGAAATACCTCATTTAAGAATAAGAACCAATACATTTGGAGCCA
TTGCTAGGGTAAGAAATAAAATTTCATACAAGATTCATGAATATTTCCAAAAAAATGGTTTTTTTTATATTAATACACCA
ATAATTACATCAAATGATGGGGAAGGTGCTGGGGAAATGTTTAGAGTTTCCACACTAAAATTTAATAAACCAAACAATTC
GCTTAGCAATATTGATTTCAAGGACGATTTTTTTGGAAAAGAAGCTTTTCTCTCTGTCACCGGTCAATTGCACGGAGAAG
CGTATGCAATGGCTTTATCTAAAATATATACATTCGGACCAACATTTCGAGCAGAAAATTCTAACACCACACGCCACGCT
TCAGAATTTTGGATGATAGAACCGGAAATGGCTTTTTACAAGCTTAACGACAATATTAGCCTAGCAGAAGATCTCTTAAA
ATACCTTTTAAGTTCAATTTTAAACGAATGCTCACAAGATATGGATTTCTTAGAAAATTACATTGAAAAAGGTTTAATTA
AAAAACTAGAAAACGTAATAAATTCCAATTTTGAAGTTATTACCTATACTAAAGCAATTGAAATTCTTGAAAGTTCAAAA
AAAAATTTTGAAATAAAACCTTGCTGGGGAATAGATTTGCAAACAGATCACGAAAGATACTTAACAGAGGAGATTTTTAA
AAAACCAATAGCAGTCATTGATTATCCAAAAAATTTCAAAGCATTTTACATGAAAATAAACAAAGACAATAAAACCGTCA
AAGGAATGGACATACTTGTTCCAAGAATTGGAGAGATTATAGGAGGAAGCGAAAGAGAAGATGACTTGCAAAAATTAGAA
AATAGAATAAAAGAATTAAACCTAAACATTGAGCATCTAAACTGGTATCTTGATCTAAGAAGATTTGGTTCTACTCCCCA
TTCTGGTTTTGGACTTGGACTTGAAAGATTGGTGCAATACACAACGGGAATATCTAATATAAGAGATTCAATACCATTCC
CAAGAACTCCTAAAAATCTTTATTTTTAA

Upstream 100 bases:

>100_bases
TTAAAATAATAAAAATTGTTGAATGTTTTTTTAAAAAAGGTTTTAAGGTATAATAAAATTGATTTAGTAATATTAATAAG
TATTTAAGGTGATAAATAAA

Downstream 100 bases:

>100_bases
TAAAATAAAAGGAAATGAGATTAATAAAACTCTACAAATTAATGCTACTCTTTCTTTTTTTAACAAGATTATTTCCAGTA
AAAGATGAAAAATCAAACAA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MFSSIKDILENPILNSNVTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFTEKDLKKLTTGASISLTGLLVE
SPAKGQNYEIKIYSFNVIGEADSKTYPLQKKRHTFEFLREIPHLRIRTNTFGAIARVRNKISYKIHEYFQKNGFFYINTP
IITSNDGEGAGEMFRVSTLKFNKPNNSLSNIDFKDDFFGKEAFLSVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHA
SEFWMIEPEMAFYKLNDNISLAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVINSNFEVITYTKAIEILESSK
KNFEIKPCWGIDLQTDHERYLTEEIFKKPIAVIDYPKNFKAFYMKINKDNKTVKGMDILVPRIGEIIGGSEREDDLQKLE
NRIKELNLNIEHLNWYLDLRRFGSTPHSGFGLGLERLVQYTTGISNIRDSIPFPRTPKNLYF

Sequences:

>Translated_462_residues
MFSSIKDILENPILNSNVTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFTEKDLKKLTTGASISLTGLLVE
SPAKGQNYEIKIYSFNVIGEADSKTYPLQKKRHTFEFLREIPHLRIRTNTFGAIARVRNKISYKIHEYFQKNGFFYINTP
IITSNDGEGAGEMFRVSTLKFNKPNNSLSNIDFKDDFFGKEAFLSVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHA
SEFWMIEPEMAFYKLNDNISLAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVINSNFEVITYTKAIEILESSK
KNFEIKPCWGIDLQTDHERYLTEEIFKKPIAVIDYPKNFKAFYMKINKDNKTVKGMDILVPRIGEIIGGSEREDDLQKLE
NRIKELNLNIEHLNWYLDLRRFGSTPHSGFGLGLERLVQYTTGISNIRDSIPFPRTPKNLYF
>Mature_462_residues
MFSSIKDILENPILNSNVTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFTEKDLKKLTTGASISLTGLLVE
SPAKGQNYEIKIYSFNVIGEADSKTYPLQKKRHTFEFLREIPHLRIRTNTFGAIARVRNKISYKIHEYFQKNGFFYINTP
IITSNDGEGAGEMFRVSTLKFNKPNNSLSNIDFKDDFFGKEAFLSVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHA
SEFWMIEPEMAFYKLNDNISLAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVINSNFEVITYTKAIEILESSK
KNFEIKPCWGIDLQTDHERYLTEEIFKKPIAVIDYPKNFKAFYMKINKDNKTVKGMDILVPRIGEIIGGSEREDDLQKLE
NRIKELNLNIEHLNWYLDLRRFGSTPHSGFGLGLERLVQYTTGISNIRDSIPFPRTPKNLYF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=447, Percent_Identity=43.4004474272931, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI4758762, Length=456, Percent_Identity=26.5350877192982, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI45439306, Length=342, Percent_Identity=28.3625730994152, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1787161, Length=462, Percent_Identity=52.8138528138528, Blast_Score=524, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI17556372, Length=438, Percent_Identity=32.1917808219178, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=452, Percent_Identity=27.4336283185841, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17551876, Length=342, Percent_Identity=28.3625730994152, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319872, Length=469, Percent_Identity=40.724946695096, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6321807, Length=460, Percent_Identity=28.695652173913, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6323011, Length=351, Percent_Identity=27.6353276353276, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19922416, Length=468, Percent_Identity=34.4017094017094, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI19921528, Length=448, Percent_Identity=25.4464285714286, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=25.9475218658892, Blast_Score=115, Evalue=9e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53167; Mature: 53167

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSSIKDILENPILNSNVTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFTE
CCCHHHHHHHCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHH
KDLKKLTTGASISLTGLLVESPAKGQNYEIKIYSFNVIGEADSKTYPLQKKRHTFEFLRE
HHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IPHLRIRTNTFGAIARVRNKISYKIHEYFQKNGFFYINTPIITSNDGEGAGEMFRVSTLK
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCCCEEEEEEEE
FNKPNNSLSNIDFKDDFFGKEAFLSVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHA
ECCCCCCCCCCCCCCCCCCCHHEEEEHHHHCCHHHHHHHHHHHHCCCCEECCCCCCCCCC
SEFWMIEPEMAFYKLNDNISLAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVI
CEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSNFEVITYTKAIEILESSKKNFEIKPCWGIDLQTDHERYLTEEIFKKPIAVIDYPKNFK
CCCCEEEEHHHHHHHHHCCCCCEEECCEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCE
AFYMKINKDNKTVKGMDILVPRIGEIIGGSEREDDLQKLENRIKELNLNIEHLNWYLDLR
EEEEEECCCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHEEEHH
RFGSTPHSGFGLGLERLVQYTTGISNIRDSIPFPRTPKNLYF
HHCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFSSIKDILENPILNSNVTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFTE
CCCHHHHHHHCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHH
KDLKKLTTGASISLTGLLVESPAKGQNYEIKIYSFNVIGEADSKTYPLQKKRHTFEFLRE
HHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
IPHLRIRTNTFGAIARVRNKISYKIHEYFQKNGFFYINTPIITSNDGEGAGEMFRVSTLK
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCCCEEEEEEEE
FNKPNNSLSNIDFKDDFFGKEAFLSVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHA
ECCCCCCCCCCCCCCCCCCCHHEEEEHHHHCCHHHHHHHHHHHHCCCCEECCCCCCCCCC
SEFWMIEPEMAFYKLNDNISLAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVI
CEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSNFEVITYTKAIEILESSKKNFEIKPCWGIDLQTDHERYLTEEIFKKPIAVIDYPKNFK
CCCCEEEEHHHHHHHHHCCCCCEEECCEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCE
AFYMKINKDNKTVKGMDILVPRIGEIIGGSEREDDLQKLENRIKELNLNIEHLNWYLDLR
EEEEEECCCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHEEEHH
RFGSTPHSGFGLGLERLVQYTTGISNIRDSIPFPRTPKNLYF
HHCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]