Click here to switch to the map view.

The map label for this gene is dppA

Identifier: 51598132

GI number: 51598132

Start: 4587661

End: 4589268

Strand: Reverse

Name: dppA

Synonym: YPTB3842

Alternate gene names: 51598132

Gene position: 4589268-4587661 (Counterclockwise)

Preceding gene: 51598133

Following gene: 51598131

Centisome position: 96.72

GC content: 48.69

Gene sequence:

>1608_bases
ATGACGATTTCCTTGAGAAGAACAGGGATACTGAAATTCGGTATTGGGCTGGTTGCACTGACTATAGCGGCCAGTGTACA
GGCAAAAACGCTAGTATATTGTTCTGAGGGGTCACCGGAAGGTTTCAACCCACAACTCTTTACTTCTGGCACAACTTATG
ACGCAAGCTCGGTACCTATTTACAATCGTTTAGTGGAGTTCAAAATCGGGACTACCGAAATTGAACCCAGCCTGGCGGAG
CGGTGGGAAGTGAGCGAAGATGGTAAAACCTACACTTTCTACCTGCGTAAGGGTGTGAAATGGCAGGATAATAAAGATTT
CAAACCCACCCGCGATTTCAATGCTGATGATGTTATCTATTCATTCATGCGTCAGAAAGATGATAAAAACCCGTACCATA
AAGTTTCTGGTGGCAGCTATGAATACTTCCAGGGTATGGGAATGGGCGACTTAATCACCAATGTGGTGAAAGTTGACGAC
AATACCGTTCGCTTTGAACTGACCCGTCCGGAATCGCCATTCTTGGCAGACCTGGCGATGGATTTCGCCTCTATCCTGTC
CGCTGAATACGCCGACAATATGCTGAAAGCAGGCACCCCGGAAAAAGTGGATTTGAACCCAATCGGTACCGGCCCATTCC
AACTGCAACAGTACCAAAAAGACTCCCGTATTCTGTATAAAGCGTTTCCTGGTTTCTGGGGCACCAAACCAAAAATTGAT
CGCCTGGTCTTCTCTATCACCCCAGATGCCTCCGTTCGCTATGCTAAATTGCAGAAAAACGAATGTCAGGTTATGCCTTA
CCCGAACCCGGCTGACATCGCCCGGATGAAAGAAGACAAAACGATTAACCTGATGGAGCAACCGGGTCTGAACGTCGGTT
ACCTCTCCTTCAACATTGAGAAGAAACCACTCGATAACCTTAAGGTCCGTCAGGCACTGACCATGGCGGTTAACAAAGAC
GCGATTATTGATGCGGTTTATCAAGGCGCGGGGCAAGCGGCCAAAAACCTGATCCCACCAACGATGTGGGGCTACAACGA
TGATGTGAAAGATTACGCTTACGATCCCGCTAAAGCGAAAGAACTGCTGAAAGAAGCGGGTCTGCCAGATGGCTTCTCCA
TCGACCTGTGGGCCATGCCGGTTCAACGTCCGTATAACCCAAATGCGCGTCGTATGGCGGAAATGATCCAGTCTGATTGG
GCGAAAATTGGTGTGAAAGCCAAGATCGTGACCTATGAGTGGGGCGAATACCTCAAGCGTGCCAAAGATGGCGAACATGA
AACTGTGATGATGGGTTGGACCGGGGACAATGGGGACCCAGACAACTTCTTCGCTACGCTGTTCAGTTGTGATGCGGCCA
AGCAGGGTTCTAACTACTCTAAATGGTGTTATAAGCCGTTTGAAGATTTGATCCAACCAGCCCGTGCTGAAGCTGACCAT
GACAAACGTGTCGCACTTTACAAACAAGCTCAGGTTGTGATGAACGAGCAGGCCCCGGCGCTGATCATTGCTCACTCAAC
GGTATACGAGCCAGTGCGTAAAGAAGTGAAAGGCTATGTTGTGGACCCATTGGGTAAACATCATTTCGATAACGTGTCCC
TGGATTAA

Upstream 100 bases:

>100_bases
TCCCTGTGTTCAACGGGCCAAAACGGCACAGTCCATGGACTAAAAAATTATAGAGTCTGGCCGTATACACAACACACATC
ACCATAATGGAGCACAAGCG

Downstream 100 bases:

>100_bases
TTTTACCCTTATACCGGACCGGTGTGCGTATCAACGTTCATCGGTCTATTTATTTAGGTTAAAACAGATACAGATGTGAG
CCATATAACCTCTCCCGGTA

Product: ABC transporter, periplasmic dipeptide binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MTISLRRTGILKFGIGLVALTIAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPIYNRLVEFKIGTTEIEPSLAE
RWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIYSFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDD
NTVRFELTRPESPFLADLAMDFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKID
RLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIEKKPLDNLKVRQALTMAVNKD
AIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAKELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDW
AKIGVKAKIVTYEWGEYLKRAKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADH
DKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLD

Sequences:

>Translated_535_residues
MTISLRRTGILKFGIGLVALTIAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPIYNRLVEFKIGTTEIEPSLAE
RWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIYSFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDD
NTVRFELTRPESPFLADLAMDFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKID
RLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIEKKPLDNLKVRQALTMAVNKD
AIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAKELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDW
AKIGVKAKIVTYEWGEYLKRAKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADH
DKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLD
>Mature_534_residues
TISLRRTGILKFGIGLVALTIAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPIYNRLVEFKIGTTEIEPSLAER
WEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIYSFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDDN
TVRFELTRPESPFLADLAMDFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKIDR
LVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIEKKPLDNLKVRQALTMAVNKDA
IIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAKELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDWA
KIGVKAKIVTYEWGEYLKRAKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADHD
KRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLD

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=535, Percent_Identity=85.0467289719626, Blast_Score=976, Evalue=0.0,
Organism=Escherichia coli, GI1787551, Length=509, Percent_Identity=35.5599214145383, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1787052, Length=548, Percent_Identity=28.8321167883212, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787762, Length=532, Percent_Identity=26.5037593984962, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1789887, Length=556, Percent_Identity=26.0791366906475, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1789397, Length=507, Percent_Identity=27.0216962524655, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787495, Length=479, Percent_Identity=23.7995824634656, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081878, Length=466, Percent_Identity=23.175965665236, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60313; Mature: 60182

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISLRRTGILKFGIGLVALTIAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPI
CEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCH
YNRLVEFKIGTTEIEPSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIY
HHEEEEEEECCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
SFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDDNTVRFELTRPESPFLADLAM
HHHHHCCCCCCCEECCCCCCHHHHCCCHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHH
DFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKID
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCC
RLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIE
EEEEEECCCCCEEEEEECCCCCEEECCCCHHHHHHHCCCCEEEHHHCCCCEEEEEEEEEC
KKPLDNLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAK
CCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHCCCHHHHH
ELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDWAKIGVKAKIVTYEWGEYLKR
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHH
AKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADH
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
DKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLD
CCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TISLRRTGILKFGIGLVALTIAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPI
EEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCH
YNRLVEFKIGTTEIEPSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIY
HHEEEEEEECCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
SFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDDNTVRFELTRPESPFLADLAM
HHHHHCCCCCCCEECCCCCCHHHHCCCHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHH
DFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKID
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCC
RLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIE
EEEEEECCCCCEEEEEECCCCCEEECCCCHHHHHHHCCCCEEEHHHCCCCEEEEEEEEEC
KKPLDNLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAK
CCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHCCCHHHHH
ELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDWAKIGVKAKIVTYEWGEYLKR
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHH
AKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADH
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
DKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLD
CCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]