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The map label for this gene is malP [H]

Identifier: 51598065

GI number: 51598065

Start: 4480263

End: 4482668

Strand: Reverse

Name: malP [H]

Synonym: YPTB3775

Alternate gene names: 51598065

Gene position: 4482668-4480263 (Counterclockwise)

Preceding gene: 51598070

Following gene: 51598064

Centisome position: 94.48

GC content: 49.58

Gene sequence:

>2406_bases
ATGTCACAGCCTATGCTTAAAAAGGACGATTTTCTGGCCGCCCTGACTCGCCAGTGGCAGCGCTTTGGCTTAACCTCCGC
TCAGCAAATGACCCCGTATCAATGGTGGGAAGCTGTCAGCGCTGCGTTAGCCGAACAGTTATCTGCTCAGCCCGCACCGA
GCAAACCAAAAAATGTACAACGCCATGTCAACTACATTTCGATGGAGTTTTTAATTGGTCGTTTGACAGCTAATAACCTA
ATTAATCTGGGTTGGTATGACACGGTGGACGCGCTGTTAGCGGAGCAGCAGGTTAAGCTGAGTGATTTGTTAGAGCAAGA
AACGGACCCAGCATTGGGCAACGGGGGCTTAGGGCGTTTGGCGGCTTGTTTTCTTGACTCAATGGCAACCGTTGAGCAAC
CGGCAACGGGCTATGGGCTGAATTATCAATATGGCCTGTTCCGCCAGTCTTTCCGTGAATGTAAACAGCAAGAAGCGCCG
GATAATTGGCAGCGGGAGAGTTACCCGTGGTTTCGCCACAATGCGGCATTGGCCGTTGATGTGGGGTTTGGCGGTAATCT
GGTCAAGCAAGCCGATGGCCGCCAATTATGGCGTCCGGCCTTTACCTTGCGCGGTGAAGCGTGGGATTTACCGGTGTTGG
GTTTCCGTAACGGCGTGACACAACCGCTACGTTTGTGGCAGGCGACGCACCAGCATCCGTTTGATTTAACCCTTTTTAAC
GATGGCAAATTCTTGCTGGCGGAACAAAATGGTGTTGAAGCAGAAAAACTGACCAAAGTACTGTACCCGAATGATAACCA
TCTGGCCGGCAAACGCCTGCGCCTGATGCAGCAATATTTCCAGTGTGCCTGTTCGGTCGCCGATATTTTGCGGAAGCACC
ATTTGGCGGGCCGTAAACTGGCTGAACTGCCGGACTATGAAGTTATTCAGCTCAACGATACCCACCCAACAATCGCTATC
CCGGAAATGCTGCGGGTCCTGCTGGATGAGCATCAACTCAGTTGGGATGCCGCTTGGGCGATTACCAGCAAAACATTCGC
TTATACCAATCATACGTTGATGCCAGAAGCCCTTGAATGCTGGGATGAAAAACTGGTACGCAGTTTGTTGCCACGCCATT
TTGTCATCATCAAGCAGATCAATGCGCAGTTTAAAAAGCTGGTGAACAAACAGTGGCCAGGCAATGACGAGGTGTGGGCC
AAACTGGCGGTACATCATAATAAACAGGTGCGGATGGCGAATCTGTGTGTGGTCAGCGGCTTTGCTGTCAACGGCGTCGC
CCAGTTGCATTCGGATCTCATTATCAAAGATCTGTTCCCTGAGTATTACCAATTGTGGCCAAATAAATTCCACAATGTAA
CGAATGGTATTACGCCGCGCCGTTGGTTGAAACAATGTAACCCGGCACTCTCTGGTTTGATTGATGACACCTTGAAGGTG
GAATGGGCCAACGATCTGGATGTTTTGCAAGACTTGGAACCCTACGCTGAGGATCCGGCTTTCCGTCAGCGTTATCAGCA
GATTAAGTATGATAACAAGGTTAAATTAGCGCATTACGTCAAGCGCGTTATGGGGCTGGTTATCAATCCCGACGCTATTT
TTGACGTACAGATTAAACGGCTACATGAATATAAACGTCAGCATTTGAATTTGTTGCATATCTTGTCGTTGTATCGCCAG
ATCCGTGACAACCCGGCACTGGATATCGCACCACGGGTGTTCCTGTTTGGTGCCAAAGCTGCACCAGGCTATTATTTAGC
CAAGAATATTATTTATGCGATTAATCAGGTTGCCGACAAGATCAACAATGATCCGATCGTTAAAGATCGTCTGAAAGTGG
TGTTTATCCCCGACTATCGTGTTTCTGTCGCCGAATTGATGATCCCCGCAGCAGATGTATCTGAACAGATATCCACAGCA
GGCAAAGAAGCCTCGGGTACCGGCAACATGAAAATGGCGCTAAATGGGGCGTTGACGGTCGGGACGCTGGACGGTGCTAA
CGTTGAAATCGCCGAGCAAGTGGGCGATGAGAATATCTTTATCTTTGGTCACACGGTTGATCAAGTGAAAGCCATTCTGG
CGAAGGGGTATCAGCCAAAGAAATACGTGAAAGCAGACCCACATCTGAAAAGTATTCTGGATGAATTGGCCAGTGGTGCG
TTCAGTCAGGGTGATAAGCAGGCATTCGACATGATGTTGCACAGCTTATTAGAGGGGGGCGACCCTTATCTGGTATTGGC
TGACTTTGCCTCCTACTGCCAGGCGCAGAAACAAATTGATGCGCTGTACCGTGATAAGGATGAGTGGACCCGCCGTGCCA
TTCTTAACACCGCCCGAGTCGGGATGTTCAGCTCTGACCGTTCTATTCGCGATTATCAACAGCGAATTTGGCAAGCCAAA
CGTTAA

Upstream 100 bases:

>100_bases
GGCTCCTCCCCAGCTAATCCCTCATCGGGATGATGCTCTTGCCAGTACTCATTGGCAGGATACGGGTAAAATTACCCATT
CACAGGATAGAGACCTCCCT

Downstream 100 bases:

>100_bases
GGAGAAGACTGCATGGATCGTAAATCGCTCGATCAAGCAGCAACACTGGCAGGGATAGCTGCCAGTTACATTAATGCGCA
TGGTAAACCGCAGGCGACGT

Product: maltodextrin phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 800

Protein sequence:

>801_residues
MSQPMLKKDDFLAALTRQWQRFGLTSAQQMTPYQWWEAVSAALAEQLSAQPAPSKPKNVQRHVNYISMEFLIGRLTANNL
INLGWYDTVDALLAEQQVKLSDLLEQETDPALGNGGLGRLAACFLDSMATVEQPATGYGLNYQYGLFRQSFRECKQQEAP
DNWQRESYPWFRHNAALAVDVGFGGNLVKQADGRQLWRPAFTLRGEAWDLPVLGFRNGVTQPLRLWQATHQHPFDLTLFN
DGKFLLAEQNGVEAEKLTKVLYPNDNHLAGKRLRLMQQYFQCACSVADILRKHHLAGRKLAELPDYEVIQLNDTHPTIAI
PEMLRVLLDEHQLSWDAAWAITSKTFAYTNHTLMPEALECWDEKLVRSLLPRHFVIIKQINAQFKKLVNKQWPGNDEVWA
KLAVHHNKQVRMANLCVVSGFAVNGVAQLHSDLIIKDLFPEYYQLWPNKFHNVTNGITPRRWLKQCNPALSGLIDDTLKV
EWANDLDVLQDLEPYAEDPAFRQRYQQIKYDNKVKLAHYVKRVMGLVINPDAIFDVQIKRLHEYKRQHLNLLHILSLYRQ
IRDNPALDIAPRVFLFGAKAAPGYYLAKNIIYAINQVADKINNDPIVKDRLKVVFIPDYRVSVAELMIPAADVSEQISTA
GKEASGTGNMKMALNGALTVGTLDGANVEIAEQVGDENIFIFGHTVDQVKAILAKGYQPKKYVKADPHLKSILDELASGA
FSQGDKQAFDMMLHSLLEGGDPYLVLADFASYCQAQKQIDALYRDKDEWTRRAILNTARVGMFSSDRSIRDYQQRIWQAK
R

Sequences:

>Translated_801_residues
MSQPMLKKDDFLAALTRQWQRFGLTSAQQMTPYQWWEAVSAALAEQLSAQPAPSKPKNVQRHVNYISMEFLIGRLTANNL
INLGWYDTVDALLAEQQVKLSDLLEQETDPALGNGGLGRLAACFLDSMATVEQPATGYGLNYQYGLFRQSFRECKQQEAP
DNWQRESYPWFRHNAALAVDVGFGGNLVKQADGRQLWRPAFTLRGEAWDLPVLGFRNGVTQPLRLWQATHQHPFDLTLFN
DGKFLLAEQNGVEAEKLTKVLYPNDNHLAGKRLRLMQQYFQCACSVADILRKHHLAGRKLAELPDYEVIQLNDTHPTIAI
PEMLRVLLDEHQLSWDAAWAITSKTFAYTNHTLMPEALECWDEKLVRSLLPRHFVIIKQINAQFKKLVNKQWPGNDEVWA
KLAVHHNKQVRMANLCVVSGFAVNGVAQLHSDLIIKDLFPEYYQLWPNKFHNVTNGITPRRWLKQCNPALSGLIDDTLKV
EWANDLDVLQDLEPYAEDPAFRQRYQQIKYDNKVKLAHYVKRVMGLVINPDAIFDVQIKRLHEYKRQHLNLLHILSLYRQ
IRDNPALDIAPRVFLFGAKAAPGYYLAKNIIYAINQVADKINNDPIVKDRLKVVFIPDYRVSVAELMIPAADVSEQISTA
GKEASGTGNMKMALNGALTVGTLDGANVEIAEQVGDENIFIFGHTVDQVKAILAKGYQPKKYVKADPHLKSILDELASGA
FSQGDKQAFDMMLHSLLEGGDPYLVLADFASYCQAQKQIDALYRDKDEWTRRAILNTARVGMFSSDRSIRDYQQRIWQAK
R
>Mature_800_residues
SQPMLKKDDFLAALTRQWQRFGLTSAQQMTPYQWWEAVSAALAEQLSAQPAPSKPKNVQRHVNYISMEFLIGRLTANNLI
NLGWYDTVDALLAEQQVKLSDLLEQETDPALGNGGLGRLAACFLDSMATVEQPATGYGLNYQYGLFRQSFRECKQQEAPD
NWQRESYPWFRHNAALAVDVGFGGNLVKQADGRQLWRPAFTLRGEAWDLPVLGFRNGVTQPLRLWQATHQHPFDLTLFND
GKFLLAEQNGVEAEKLTKVLYPNDNHLAGKRLRLMQQYFQCACSVADILRKHHLAGRKLAELPDYEVIQLNDTHPTIAIP
EMLRVLLDEHQLSWDAAWAITSKTFAYTNHTLMPEALECWDEKLVRSLLPRHFVIIKQINAQFKKLVNKQWPGNDEVWAK
LAVHHNKQVRMANLCVVSGFAVNGVAQLHSDLIIKDLFPEYYQLWPNKFHNVTNGITPRRWLKQCNPALSGLIDDTLKVE
WANDLDVLQDLEPYAEDPAFRQRYQQIKYDNKVKLAHYVKRVMGLVINPDAIFDVQIKRLHEYKRQHLNLLHILSLYRQI
RDNPALDIAPRVFLFGAKAAPGYYLAKNIIYAINQVADKINNDPIVKDRLKVVFIPDYRVSVAELMIPAADVSEQISTAG
KEASGTGNMKMALNGALTVGTLDGANVEIAEQVGDENIFIFGHTVDQVKAILAKGYQPKKYVKADPHLKSILDELASGAF
SQGDKQAFDMMLHSLLEGGDPYLVLADFASYCQAQKQIDALYRDKDEWTRRAILNTARVGMFSSDRSIRDYQQRIWQAKR

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI5032009, Length=748, Percent_Identity=43.716577540107, Blast_Score=632, Evalue=0.0,
Organism=Homo sapiens, GI21361370, Length=781, Percent_Identity=43.2778489116517, Blast_Score=630, Evalue=1e-180,
Organism=Homo sapiens, GI71037379, Length=751, Percent_Identity=43.8082556591212, Blast_Score=623, Evalue=1e-178,
Organism=Homo sapiens, GI255653002, Length=691, Percent_Identity=43.849493487699, Blast_Score=607, Evalue=1e-173,
Organism=Homo sapiens, GI257900462, Length=653, Percent_Identity=43.7978560490046, Blast_Score=578, Evalue=1e-165,
Organism=Escherichia coli, GI48994936, Length=802, Percent_Identity=75.4364089775561, Blast_Score=1257, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=743, Percent_Identity=46.164199192463, Blast_Score=687, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=751, Percent_Identity=46.6045272969374, Blast_Score=698, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=751, Percent_Identity=46.6045272969374, Blast_Score=697, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=811, Percent_Identity=42.4167694204686, Blast_Score=587, Evalue=1e-168,
Organism=Drosophila melanogaster, GI78706832, Length=748, Percent_Identity=45.7219251336898, Blast_Score=664, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=748, Percent_Identity=45.7219251336898, Blast_Score=664, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 91180; Mature: 91049

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPMLKKDDFLAALTRQWQRFGLTSAQQMTPYQWWEAVSAALAEQLSAQPAPSKPKNVQ
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
RHVNYISMEFLIGRLTANNLINLGWYDTVDALLAEQQVKLSDLLEQETDPALGNGGLGRL
HHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AACFLDSMATVEQPATGYGLNYQYGLFRQSFRECKQQEAPDNWQRESYPWFRHNAALAVD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCEEEEE
VGFGGNLVKQADGRQLWRPAFTLRGEAWDLPVLGFRNGVTQPLRLWQATHQHPFDLTLFN
ECCCCCHHCCCCCCHHHCCHHEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEC
DGKFLLAEQNGVEAEKLTKVLYPNDNHLAGKRLRLMQQYFQCACSVADILRKHHLAGRKL
CCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AELPDYEVIQLNDTHPTIAIPEMLRVLLDEHQLSWDAAWAITSKTFAYTNHTLMPEALEC
HCCCCCEEEEECCCCCCEEHHHHHHHHHHHHCCCCHHHEEEECCEEEECCCCCCHHHHHH
WDEKLVRSLLPRHFVIIKQINAQFKKLVNKQWPGNDEVWAKLAVHHNKQVRMANLCVVSG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEHEEEEEC
FAVNGVAQLHSDLIIKDLFPEYYQLWPNKFHNVTNGITPRRWLKQCNPALSGLIDDTLKV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCHHHHHHHCCCEEE
EWANDLDVLQDLEPYAEDPAFRQRYQQIKYDNKVKLAHYVKRVMGLVINPDAIFDVQIKR
EECCCHHHHHHCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCEEECCCCEEHHHHHH
LHEYKRQHLNLLHILSLYRQIRDNPALDIAPRVFLFGAKAAPGYYLAKNIIYAINQVADK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
INNDPIVKDRLKVVFIPDYRVSVAELMIPAADVSEQISTAGKEASGTGNMKMALNGALTV
CCCCCCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEE
GTLDGANVEIAEQVGDENIFIFGHTVDQVKAILAKGYQPKKYVKADPHLKSILDELASGA
EECCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
FSQGDKQAFDMMLHSLLEGGDPYLVLADFASYCQAQKQIDALYRDKDEWTRRAILNTARV
CCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
GMFSSDRSIRDYQQRIWQAKR
CCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQPMLKKDDFLAALTRQWQRFGLTSAQQMTPYQWWEAVSAALAEQLSAQPAPSKPKNVQ
CCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
RHVNYISMEFLIGRLTANNLINLGWYDTVDALLAEQQVKLSDLLEQETDPALGNGGLGRL
HHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AACFLDSMATVEQPATGYGLNYQYGLFRQSFRECKQQEAPDNWQRESYPWFRHNAALAVD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCEEEEE
VGFGGNLVKQADGRQLWRPAFTLRGEAWDLPVLGFRNGVTQPLRLWQATHQHPFDLTLFN
ECCCCCHHCCCCCCHHHCCHHEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEC
DGKFLLAEQNGVEAEKLTKVLYPNDNHLAGKRLRLMQQYFQCACSVADILRKHHLAGRKL
CCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AELPDYEVIQLNDTHPTIAIPEMLRVLLDEHQLSWDAAWAITSKTFAYTNHTLMPEALEC
HCCCCCEEEEECCCCCCEEHHHHHHHHHHHHCCCCHHHEEEECCEEEECCCCCCHHHHHH
WDEKLVRSLLPRHFVIIKQINAQFKKLVNKQWPGNDEVWAKLAVHHNKQVRMANLCVVSG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEHEEEEEC
FAVNGVAQLHSDLIIKDLFPEYYQLWPNKFHNVTNGITPRRWLKQCNPALSGLIDDTLKV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCHHHHHHHCCCEEE
EWANDLDVLQDLEPYAEDPAFRQRYQQIKYDNKVKLAHYVKRVMGLVINPDAIFDVQIKR
EECCCHHHHHHCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCEEECCCCEEHHHHHH
LHEYKRQHLNLLHILSLYRQIRDNPALDIAPRVFLFGAKAAPGYYLAKNIIYAINQVADK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
INNDPIVKDRLKVVFIPDYRVSVAELMIPAADVSEQISTAGKEASGTGNMKMALNGALTV
CCCCCCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEE
GTLDGANVEIAEQVGDENIFIFGHTVDQVKAILAKGYQPKKYVKADPHLKSILDELASGA
EECCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
FSQGDKQAFDMMLHSLLEGGDPYLVLADFASYCQAQKQIDALYRDKDEWTRRAILNTARV
CCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
GMFSSDRSIRDYQQRIWQAKR
CCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3037809; 9278503; 3155826; 2845225; 6283313; 6339728; 6986282; 9009262; 10220320; 10469642 [H]