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The map label for this gene is slyD

Identifier: 51598002

GI number: 51598002

Start: 4406945

End: 4407538

Strand: Reverse

Name: slyD

Synonym: YPTB3712

Alternate gene names: 51598002

Gene position: 4407538-4406945 (Counterclockwise)

Preceding gene: 51598003

Following gene: 51598000

Centisome position: 92.89

GC content: 52.36

Gene sequence:

>594_bases
ATGAAAGTAACAAAAGACTTGGTAGTCAGCCTGGCTTACCAGGTACGTACAGAAGACGGTGTTTTAGTTGATGAGTCTCC
GGTGAGCGCGCCGTTGGACTACCTGCACGGGCACGGTTCCCTGATCGCTGGTTTAGAAAACGCGCTCGAAGGCCACGAAG
CTGGTGACAGTTTTGATGTGCGTGTTAATGCCGATGAAGGTTACGGCAGCTACGATGAAAATCTGGTGCAGCGTGTACCA
AAAGACGTCTTTATGGGCGTTGACGAGCTGGAAGTGGGGATGCGTTTTCTGGCAGATACTGATCAAGGCCCAGTACCGGT
TGAGATCACTGCTGTCGAAGACGAGCACGTCGTGGTTGATGGTAACCACATGCTGGCGGGCCAGGATCTGAACTTCCACG
TTGAAGTGGTTGCTGTCCGTGAAGCAACAGAAGAAGAGTTGCAGCACGGCCATGTACATGGTGAGCATGATCATCACCAT
GAACACGGTGACGGTTGCTGCGGTGGTCACGGCCACGACGACCATGAACATGAACATGAACATGAGCATGGTAAAGGTGG
TTGCGGTAAAAGTGGCGGTTGTGGCTGTCACTAA

Upstream 100 bases:

>100_bases
GAGTAGCGTTATCTGCCGTGATTTTTTATGCGGGTGAGTACAGCGGGGCAGATTTCCGCTACAATCTGTGCCAATTTTTG
TTCCAAGGGTAGGAGATATC

Downstream 100 bases:

>100_bases
TATCTGACCCCGTCAGCAAAAAGCCAGCCTTCATCGCTGGCTTTTTACTCTGTACGCGATCACTCATTTTCTGTGTGATA
GCCAATGATCTCGTCATAAC

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDVRVNADEGYGSYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVDGNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHH
EHGDGCCGGHGHDDHEHEHEHEHGKGGCGKSGGCGCH

Sequences:

>Translated_197_residues
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDVRVNADEGYGSYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVDGNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHH
EHGDGCCGGHGHDDHEHEHEHEHGKGGCGKSGGCGCH
>Mature_197_residues
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDVRVNADEGYGSYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVDGNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHH
EHGDGCCGGHGHDDHEHEHEHEHGKGGCGKSGGCGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=87.7551020408163, Blast_Score=261, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21318; Mature: 21318

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDV
CCCHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCEEE
RVNADEGYGSYDENLVQRVPKDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVD
EEECCCCCCCHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEE
GNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHHEHGDGCCGGHGHDDHEHEHE
CCEEEECCCCCEEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
HEHGKGGCGKSGGCGCH
HCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDV
CCCHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCEEE
RVNADEGYGSYDENLVQRVPKDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVD
EEECCCCCCCHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEE
GNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHHEHGDGCCGGHGHDDHEHEHE
CCEEEECCCCCEEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
HEHGKGGCGKSGGCGCH
HCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]