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The map label for this gene is sstT [H]

Identifier: 51597766

GI number: 51597766

Start: 4139377

End: 4140633

Strand: Direct

Name: sstT [H]

Synonym: YPTB3474

Alternate gene names: 51597766

Gene position: 4139377-4140633 (Clockwise)

Preceding gene: 51597765

Following gene: 51597771

Centisome position: 87.24

GC content: 48.53

Gene sequence:

>1257_bases
ATGGAAAAGACACAGTCTGTATTTATACGATTTATCGTCAACGGTAGTTTAGTGAAACAAATACTGATCGGTTTAGTTGC
CGGTATTGTTTTAGCATTAGTATCGACTCCTGCAGCGATAGCGGTAGGGTTACTCGGTTCGCTGTTCGTGGGCGCATTAA
AAGCCGTCGCGCCAGTTTTAGTCTTGATGTTGGTCATAGCATCCATCGCCAACCATAAGAAAGGCCAAAAAACCAGTATT
CGCCCTATTCTGTTCCTGTATGTATTAGGGACATTCTCTGCGGCACTGGTTGCGGTTGTCGTCAGTTTTATCTACCCATC
AACCCTTATTTTGGTGGCTGAGAGTGCTGATATCACCCCACCGAGTGGGATTGTTGAAGTGCTACACGGTTTGCTAAACA
GCATAATCGCCAACCCTATCCATGCGCTGCTCAATGCTAACTACATTGGTATTCTGGCTTGGGCTGTGGGTTTAGGTATT
GCCTTGCGTCATGCTGCCGATACCACCAAAGCATTGATTAATGATATGTCAGATGCCGTCACTTTGGTGGTCCGTGTGGT
TATCCGTTTTGCACCGTTGGGTATTTTTGGTTTGGTCGCGTCCACTATCGCAGCTACCGGCTTCGGTGCCTTACAGCTTT
ATGCGCAACTGTTAGTGGTATTGATCGGCTGTATGTTACTGGTGGCATTAGTGGTCAACCCACTGATTGTTTACTGGAAG
ATTCGCCGTAATCCTTATCCATTGGTATTTGCTTGCCTGCGTGAAAGTGGCGTTACTGCCTTCTTTACCCGGAGTTCAGC
CGCAAACATTCCAGTGAATATGGAAATGTGTAAGAAAATGAACCTGAATGAAGACACCTATTCGATCTCTATTCCGTTAG
GTGCCACCATTAATATGGCTGGTGCAGCCATCACCATCACGGTGCTGACACTGGCGGCGGTTCATACCCTAGGCATTACC
GTTGACCTGCCAACAGCCCTGCTACTGAGTGTGGTTGCGGCGATCTGTGCCTGTGGTGCATCCGGTGTTGCCGGTGGCTC
TCTGTTACTGATCCCACTGGCTTGCAGCATGTTCGGCATTCCAAACGATGTGGCAATGCAAGTGGTTGGTGTTGGCTTCA
TTATCGGCGTATTGCAGGATTCAGCCGAAACTGCACTGAACTCTTCAACCGATGTGTTGTTTACTGCAGCGGTCTGTCAG
GCTGAGGATGCCAAACTGGCTAATCCTGACCCACTGGCAGCGGGTAAGTCAGTCTAA

Upstream 100 bases:

>100_bases
GTATGGAGAGCAGCTAGCACCGCTGCAACTTCAGGTAATGAAGGGTATAAACGGGCAGAACATATTAAATTTCACTTGGG
AAGAGGCATTGCTAGAAGCT

Downstream 100 bases:

>100_bases
ATACTCGGTTTTACCTACGCAAAATGCCAGTCAGTTAAGTTTGACTGGCATTTTTTTGTTATCAAATCAGGCCTTTTTCT
CAATCTCAAAAGGATCTATT

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSI
RPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGI
ALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLVVLIGCMLLVALVVNPLIVYWK
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGIT
VDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQ
AEDAKLANPDPLAAGKSV

Sequences:

>Translated_418_residues
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSI
RPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGI
ALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLVVLIGCMLLVALVVNPLIVYWK
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGIT
VDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQ
AEDAKLANPDPLAAGKSV
>Mature_418_residues
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSI
RPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGI
ALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLVVLIGCMLLVALVVNPLIVYWK
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGIT
VDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQ
AEDAKLANPDPLAAGKSV

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI223468566, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI5032093, Length=254, Percent_Identity=28.3464566929134, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4827012, Length=243, Percent_Identity=24.2798353909465, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI169790839, Length=288, Percent_Identity=24.3055555555556, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI66773030, Length=272, Percent_Identity=24.6323529411765, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI21314632, Length=259, Percent_Identity=27.4131274131274, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI40254478, Length=273, Percent_Identity=26.007326007326, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789473, Length=407, Percent_Identity=77.1498771498772, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1790514, Length=439, Percent_Identity=23.6902050113895, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789947, Length=391, Percent_Identity=24.2966751918159, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17537407, Length=471, Percent_Identity=23.3545647558386, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71983099, Length=276, Percent_Identity=25.3623188405797, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=276, Percent_Identity=25.3623188405797, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71996953, Length=269, Percent_Identity=26.7657992565056, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=292, Percent_Identity=27.7397260273973, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24583025, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17137668, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583023, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43202; Mature: 43202

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVL
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITP
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCC
PSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLVVLIGCMLLVALVVNPLIVYWK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMA
ECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCEEECC
GAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGI
CHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
PNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQAEDAKLANPDPLAAGKSV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVL
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITP
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCC
PSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLVVLIGCMLLVALVVNPLIVYWK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMA
ECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCEEECC
GAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGI
CHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
PNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQAEDAKLANPDPLAAGKSV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA