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The map label for this gene is yafC [H]

Identifier: 51597692

GI number: 51597692

Start: 4031468

End: 4032379

Strand: Reverse

Name: yafC [H]

Synonym: YPTB3394

Alternate gene names: 51597692

Gene position: 4032379-4031468 (Counterclockwise)

Preceding gene: 51597693

Following gene: 51597690

Centisome position: 84.99

GC content: 53.18

Gene sequence:

>912_bases
ATGAAAGTCACGTTGGAAGAGTTGCAGGCATTTACCTCGGTAGTGGACTGCGGCTCTATCACGGCTGCGGCAGAGCAGCG
CAGCCAAACGACATCGGGGATTAGCCGGGCATTGAGTCGGCTAGAGCAGAAGCTGGCGACAACGTTGCTACGCCGTACGA
CTCGGCGTCTGGAGCTGACAGAAGAGGGGGCGCTGTTCCTCAGTCATGCGCGGCAGATTATCGGCGCAGTCGATGATGCT
GAAGAGCAAATTGCCCTGAGGCGGTTGAAGCCTGCTGGCCGGTTACGAGTTAATGCGGCAGCTCCTTTTATGCAACATGT
CATTGTGCCGATGATCACCGGTTTCCGTGCGTTGTATCCGCAAATCACGTTGGAATTGAATACCGACGATCTCAATATCG
ATCTGCTTGAGCAGCGCACTGACATTGCTATCCGTATCGGTGCGTTGAGGGATTCGACGATCCATGCCCGGCTGCTTGGT
GCCAGCCGGGTGCGTCTGCTTGCCAGCCCTAACTACCTACAACGTCACGGTACGCCTCACACCATTGAGGCACTGGCAGA
TCACAGCCTGCTGGGCTTTACTCAGCCCGAATTTCTTAATCAGTGGTCATTACCCCATTTACCCGGCGGGCGTTCGTCAA
TTATCCCCAACTTGGCGGCTTCCAGCGGTGAGACTCTGCGTTTACTGGCTTTACAGGGCGAAGGGATTGCCGAACTCTCT
GATTTCATGACCCGCGAGGATCAATTAGCTGGGCGTTTAGTCGAGGTTCTGGCTGATCAAATTCTAGAGACTTGGCAACC
GATCAACGCCGTTTATTACCGTAATACTCAGCTTGCTGCGCGCATTACCTGTTTTCTTGATTATGTTAGTGAACAGATTA
AGTTACAGGGGAGTCACTGGCTAAGAATATAA

Upstream 100 bases:

>100_bases
TCTGGCCGTTATGGATATGTTGTTGGCAAAGAAACGCTCGGAAGATCGCCGCAACTGGCTACAAGAGAAAGGGGATACTG
CTGAGATCGAGGTCTGATCG

Downstream 100 bases:

>100_bases
ATGAGGGAGGGGTAACGTATAAAACGGCCCTCCCCAGAGAGAGGAGGGCCGAACCGCTTAGCTGTTAACGTTTTCGGCTA
AGTGCTGACGATAGCGGGCA

Product: LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHTIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI

Sequences:

>Translated_303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHTIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI
>Mature_303_residues
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELTEEGALFLSHARQIIGAVDDA
EEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYPQITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLG
ASRVRLLASPNYLQRHGTPHTIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHWLRI

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=43.8775510204082, Blast_Score=254, Evalue=5e-69,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=30.5369127516779, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI145693193, Length=303, Percent_Identity=29.042904290429, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789440, Length=277, Percent_Identity=29.2418772563177, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=28.8659793814433, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=28.4745762711864, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787589, Length=304, Percent_Identity=25, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789173, Length=272, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=27.0903010033445, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788706, Length=304, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787879, Length=162, Percent_Identity=32.0987654320988, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=26.3565891472868, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786448, Length=184, Percent_Identity=27.1739130434783, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33731; Mature: 33731

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
EEGALFLSHARQIIGAVDDAEEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
QITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLGASRVRLLASPNYLQRHGTPH
EEEEEECCCCCCEEHHHCCCCEEEEEECCCCCHHHHHHHCHHHEEEEECCCHHHHCCCCH
TIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
HHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCHHCCCCCEEEEEEECCCCHHHHH
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCCE
LRI
ECC
>Mature Secondary Structure
MKVTLEELQAFTSVVDCGSITAAAEQRSQTTSGISRALSRLEQKLATTLLRRTTRRLELT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
EEGALFLSHARQIIGAVDDAEEQIALRRLKPAGRLRVNAAAPFMQHVIVPMITGFRALYP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
QITLELNTDDLNIDLLEQRTDIAIRIGALRDSTIHARLLGASRVRLLASPNYLQRHGTPH
EEEEEECCCCCCEEHHHCCCCEEEEEECCCCCHHHHHHHCHHHEEEEECCCHHHHCCCCH
TIEALADHSLLGFTQPEFLNQWSLPHLPGGRSSIIPNLAASSGETLRLLALQGEGIAELS
HHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCHHCCCCCEEEEEEECCCCHHHHH
DFMTREDQLAGRLVEVLADQILETWQPINAVYYRNTQLAARITCFLDYVSEQIKLQGSHW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCCE
LRI
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]