Click here to switch to the map view.

The map label for this gene is rbsR [H]

Identifier: 51597572

GI number: 51597572

Start: 3854924

End: 3855919

Strand: Direct

Name: rbsR [H]

Synonym: YPTB3270

Alternate gene names: 51597572

Gene position: 3854924-3855919 (Clockwise)

Preceding gene: 51597569

Following gene: 51597573

Centisome position: 81.25

GC content: 46.18

Gene sequence:

>996_bases
ATGAGCCACATTGCGGCCAAAGCGGGAGTATCACAATCAACAGTTTCATTGGTGTTAAACGGCTCTTACAGCATCAAACT
GGCAGATGACACCAGAGAAAAAGTCCTGCGTATTGCTCAGGAGATGGGCTATGTTCATAAAGCCGTGGAACGGCCCATTG
CCAGAGATAAAATAGCATTAATTATCAATGGGCTAATAAACCACGATCCTTTCATTGAAGCGATCAGTGCTGTTCAACAG
GCAGCCTGGCAACACAACAAGCTATTGGCGATTTTTGATCAGGAAAATGAACCAGAGCACTGCGCAGCACTTGAAGAGGA
AATCTGTCGAGGAGGTTATCAGGGGGTAATTTACGCCTCTTGCATGACCAGCCAGCTAGCGCCGATGTTTCGTAATCTGT
CCATCCCAATGGTAATGCTGAATGGTTATTGCCCTGAGCTACCTGATGTTCCCTGTATTTTACCCGCAGATAAAATTGGC
GCTTATAAGGCTACCAGCCATTTATTGCAACAGGGATATAAACGGATTGCCATTCTGGCTGGCGAACTGTGGATGGATGC
CGCCAACGACCGTATTAGTGGCTACCGGCAGGCACTCATCAACCATGATATTTGCCCTGATGAAGGTTATATCCAGGTGA
CAAACTGGTCATTGAAGGAAGCGTATAAAAAAACACTGGAATTGCTGGCACTCACTGCCAGACCAGAAGCCATTTTCTGC
AGTAGTGACTATATAGCACTCGGGTGTTATCAGGCGATTTTGTCACAAGGGTTGCGCATTCCCGATGATATCGCCGTCGT
GGGCTATGATAATCAAAGTATTTCTTCCGAACTGTCGCCAGAATTAAGCTCAGTAGACTTACCTTACGGTGAAATGGGTG
AAATAGCGCTGCATACCTTACTCAACATCACGCAGCAGCAACCCTTGCTGTCATTGAAAATGAAGGTAGAAGGCGAGTTG
GTTATCCGACAGTCTTCAATAAGACCAGAGAAATAG

Upstream 100 bases:

>100_bases
GACCCTGATGAACAGTCCTGCTAGCTAAAATCTGTTAGTATAAAAAAAGATGAAATATAGCCAGTATGAGTAAAATATGA
ATAAAAAAACGAAAGTGACT

Downstream 100 bases:

>100_bases
CCTACCCCGCGCCAGCCTCCATTTAATTGGGCACGGCTCCTAATTGAGAATAACGCCTCCTCTCAATTGAGAACAATGCC
CACGTTCAATTAAGAACAGC

Product: LacI-family regulatory protein.

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIALIINGLINHDPFIEAISAVQQ
AAWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPCILPADKIG
AYKATSHLLQQGYKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALTARPEAIFC
SSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVDLPYGEMGEIALHTLLNITQQQPLLSLKMKVEGEL
VIRQSSIRPEK

Sequences:

>Translated_331_residues
MSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIALIINGLINHDPFIEAISAVQQ
AAWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPCILPADKIG
AYKATSHLLQQGYKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALTARPEAIFC
SSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVDLPYGEMGEIALHTLLNITQQQPLLSLKMKVEGEL
VIRQSSIRPEK
>Mature_330_residues
SHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIALIINGLINHDPFIEAISAVQQA
AWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYASCMTSQLAPMFRNLSIPMVMLNGYCPELPDVPCILPADKIGA
YKATSHLLQQGYKRIAILAGELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALTARPEAIFCS
SDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVDLPYGEMGEIALHTLLNITQQQPLLSLKMKVEGELV
IRQSSIRPEK

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=337, Percent_Identity=31.1572700296736, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=28.0120481927711, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=25.9818731117825, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787580, Length=314, Percent_Identity=27.3885350318471, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789202, Length=332, Percent_Identity=28.0120481927711, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788474, Length=300, Percent_Identity=30, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789068, Length=345, Percent_Identity=25.5072463768116, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786540, Length=343, Percent_Identity=26.8221574344023, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787906, Length=278, Percent_Identity=27.6978417266187, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994940, Length=319, Percent_Identity=23.5109717868339, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790715, Length=308, Percent_Identity=22.0779220779221, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36586; Mature: 36454

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIAL
CCCCHHHCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IINGLINHDPFIEAISAVQQAAWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYAS
HHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEHH
CMTSQLAPMFRNLSIPMVMLNGYCPELPDVPCILPADKIGAYKATSHLLQQGYKRIAILA
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHHHH
GELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALTARPEAIFC
HHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEE
SSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVDLPYGEMGEIALHTL
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCCHHCCCCCCCCHHHHHHHHH
LNITQQQPLLSLKMKVEGELVIRQSSIRPEK
HHHHHCCCCEEEEEEECCEEEEEECCCCCCC
>Mature Secondary Structure 
SHIAAKAGVSQSTVSLVLNGSYSIKLADDTREKVLRIAQEMGYVHKAVERPIARDKIAL
CCCHHHCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IINGLINHDPFIEAISAVQQAAWQHNKLLAIFDQENEPEHCAALEEEICRGGYQGVIYAS
HHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEHH
CMTSQLAPMFRNLSIPMVMLNGYCPELPDVPCILPADKIGAYKATSHLLQQGYKRIAILA
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHHHH
GELWMDAANDRISGYRQALINHDICPDEGYIQVTNWSLKEAYKKTLELLALTARPEAIFC
HHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEE
SSDYIALGCYQAILSQGLRIPDDIAVVGYDNQSISSELSPELSSVDLPYGEMGEIALHTL
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCCHHCCCCCCCCHHHHHHHHH
LNITQQQPLLSLKMKVEGELVIRQSSIRPEK
HHHHHCCCCEEEEEEECCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]