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The map label for this gene is glsA1 [H]

Identifier: 51597531

GI number: 51597531

Start: 3793978

End: 3794904

Strand: Reverse

Name: glsA1 [H]

Synonym: YPTB3221

Alternate gene names: 51597531

Gene position: 3794904-3793978 (Counterclockwise)

Preceding gene: 51597532

Following gene: 51597530

Centisome position: 79.98

GC content: 48.65

Gene sequence:

>927_bases
GTGGTAACAACGTTAGATAATGCCTTACTAAACGATATATTACAGCAGGTCCGCCCGTTGATTGGTCAGGGTAAAGTCGC
TGATTATATTCCCGCACTGGCGGAGGTTCCGGCCAATAAGCTGGGAATTGCCGTTTGTACACTGGATGGTCAGATATTTC
AGGCAGGGGATGCCGATGAACGCTTCTCTATCCAATCGATTTCTAAAGTATTAAGTCTGACGCTGGCCTTATCCCGTTAC
AGTGAGCAAGATATTTGGCAGCGGGTGGGTAAAGAGCCTTCTGGCCAGCCATTCAACTCATTGGTTCAGTTGGAGTTAGA
AAAGGGAAAACCCCGTAACCCATTTATTAATCCAGGGGCGCTGGTGGTCTGCGATATGTTGCAAAGCCGCCTGAGTGCCC
CAAAACAACGTCTGTTGGAAGTTGTACGCCAGTTAGTGAAGGATGACAGCATCAGTTACGATCCTCGTGTGGCGCGTTCC
GAATTTGAGCATTCAGATCGCAATGCGGCTATTGCTTATCTAATGAAGTCTTTTGGTAATTTCGATAACGACGTATTGAC
GGTATTGCAGACCTATTTCCACTACTGTGCGATGCGTATGAGCTGTGTCGAGTTGGCCCGTTGCTTTGTTTATCTGGCGA
ATCAGGGGCGCAGCATCAGTGGCTCCGAGTCTTTAATTACCCCAATGCAGGCGCGGCAAATTAATGCTCTGATGATCACT
AGCGGCATGTATGATGGTGCAGGGGAGTTTGCCTTCCGAGTCGGGATGCCGGGTAAATCGGGGGTTGGTGGTGGTATTAT
TGCCATTGTTCCGGATGAGTTCTGTATTGCCGTTTGGTCACCTGAATTGGATCATGCAGGGAACTCATTGGCGGGTACCG
CTGCCTTAGAGAGATTGGCGCAACAAATTGGTCGTTCTATCTTTTAA

Upstream 100 bases:

>100_bases
TAACGGCTGATCATTAAACAGGGCGCCCTAACCGGCGCCTTTGTTTTTACTGGCTGTAATTAGTGGAAATTGTTAGCGGG
TTTTTATTGGGAGCCTTGTA

Downstream 100 bases:

>100_bases
GACAGCTCTTCTTCTGCTTAAAGATAAGTTCTGGCAGAGTATAGAGATAGACCAAAGTACTCGAGGTTGCAGTCAGGCAG
CAATCGAATGGCACAATTTT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MVTTLDNALLNDILQQVRPLIGQGKVADYIPALAEVPANKLGIAVCTLDGQIFQAGDADERFSIQSISKVLSLTLALSRY
SEQDIWQRVGKEPSGQPFNSLVQLELEKGKPRNPFINPGALVVCDMLQSRLSAPKQRLLEVVRQLVKDDSISYDPRVARS
EFEHSDRNAAIAYLMKSFGNFDNDVLTVLQTYFHYCAMRMSCVELARCFVYLANQGRSISGSESLITPMQARQINALMIT
SGMYDGAGEFAFRVGMPGKSGVGGGIIAIVPDEFCIAVWSPELDHAGNSLAGTAALERLAQQIGRSIF

Sequences:

>Translated_308_residues
MVTTLDNALLNDILQQVRPLIGQGKVADYIPALAEVPANKLGIAVCTLDGQIFQAGDADERFSIQSISKVLSLTLALSRY
SEQDIWQRVGKEPSGQPFNSLVQLELEKGKPRNPFINPGALVVCDMLQSRLSAPKQRLLEVVRQLVKDDSISYDPRVARS
EFEHSDRNAAIAYLMKSFGNFDNDVLTVLQTYFHYCAMRMSCVELARCFVYLANQGRSISGSESLITPMQARQINALMIT
SGMYDGAGEFAFRVGMPGKSGVGGGIIAIVPDEFCIAVWSPELDHAGNSLAGTAALERLAQQIGRSIF
>Mature_308_residues
MVTTLDNALLNDILQQVRPLIGQGKVADYIPALAEVPANKLGIAVCTLDGQIFQAGDADERFSIQSISKVLSLTLALSRY
SEQDIWQRVGKEPSGQPFNSLVQLELEKGKPRNPFINPGALVVCDMLQSRLSAPKQRLLEVVRQLVKDDSISYDPRVARS
EFEHSDRNAAIAYLMKSFGNFDNDVLTVLQTYFHYCAMRMSCVELARCFVYLANQGRSISGSESLITPMQARQINALMIT
SGMYDGAGEFAFRVGMPGKSGVGGGIIAIVPDEFCIAVWSPELDHAGNSLAGTAALERLAQQIGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=273, Percent_Identity=36.6300366300366, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=34.3537414965986, Blast_Score=167, Evalue=9e-42,
Organism=Escherichia coli, GI1787804, Length=308, Percent_Identity=74.6753246753247, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=37.7622377622378, Blast_Score=201, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17507019, Length=297, Percent_Identity=36.3636363636364, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17532727, Length=298, Percent_Identity=34.2281879194631, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI193204073, Length=290, Percent_Identity=35.5172413793103, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI193204075, Length=292, Percent_Identity=35.2739726027397, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=37.1929824561403, Blast_Score=190, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=37.1929824561403, Blast_Score=190, Evalue=9e-49,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=37.1929824561403, Blast_Score=190, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=37.1929824561403, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=37.1929824561403, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=37.1929824561403, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=37.1929824561403, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=37.1929824561403, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33666; Mature: 33666

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTLDNALLNDILQQVRPLIGQGKVADYIPALAEVPANKLGIAVCTLDGQIFQAGDADE
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEEEEEEECCCEEECCCCCC
RFSIQSISKVLSLTLALSRYSEQDIWQRVGKEPSGQPFNSLVQLELEKGKPRNPFINPGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCCCCCCH
LVVCDMLQSRLSAPKQRLLEVVRQLVKDDSISYDPRVARSEFEHSDRNAAIAYLMKSFGN
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCC
FDNDVLTVLQTYFHYCAMRMSCVELARCFVYLANQGRSISGSESLITPMQARQINALMIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHCCEEEEE
SGMYDGAGEFAFRVGMPGKSGVGGGIIAIVPDEFCIAVWSPELDHAGNSLAGTAALERLA
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCHHHCCCCHHHHHHHHHHH
QQIGRSIF
HHHHHCCC
>Mature Secondary Structure
MVTTLDNALLNDILQQVRPLIGQGKVADYIPALAEVPANKLGIAVCTLDGQIFQAGDADE
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEEEEEEECCCEEECCCCCC
RFSIQSISKVLSLTLALSRYSEQDIWQRVGKEPSGQPFNSLVQLELEKGKPRNPFINPGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCCCCCCH
LVVCDMLQSRLSAPKQRLLEVVRQLVKDDSISYDPRVARSEFEHSDRNAAIAYLMKSFGN
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCC
FDNDVLTVLQTYFHYCAMRMSCVELARCFVYLANQGRSISGSESLITPMQARQINALMIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHCCEEEEE
SGMYDGAGEFAFRVGMPGKSGVGGGIIAIVPDEFCIAVWSPELDHAGNSLAGTAALERLA
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCHHHCCCCHHHHHHHHHHH
QQIGRSIF
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]