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The map label for this gene is mutH

Identifier: 51597352

GI number: 51597352

Start: 3585642

End: 3586328

Strand: Direct

Name: mutH

Synonym: YPTB3037

Alternate gene names: 51597352

Gene position: 3585642-3586328 (Clockwise)

Preceding gene: 51597338

Following gene: 51597353

Centisome position: 75.57

GC content: 52.69

Gene sequence:

>687_bases
ATGTCTGTTTACTCTTTGCCTCCTGCTCCCCCCAGTGATGAACATCAACTTTTTCAACGTGCGCAGGCATTGTCTGGTTT
TACCCTTGGTGAATTAGCAACACGTGCCCAGTGGGTCATCCCCGCAGACCTAAAACGCGTAAAAGGTTGGGTTGGGATGC
TGTTGGAGTTCTATCTAGGCGCCAGTGCTGGCAGTAAACCAGAGCAGGATTTCGCCGATATCGGCATCGAGCTGAAAACC
ATCCCGATCAGTGCACAAGGAAAACCACTGGAAACGACATTCGTCTGCGTGGCACCACTCACCGGGAATAGCGGTGTCAC
CTGGGAAAATAGCCATGTGCGTCATAAGCTTGCCAGAGTGTTGTGGGTGCCCGTCGAAGGTGAACGGCATATTCCGTTAG
CAGAACGCCGAGTCGGTGCTCCGCTGCTGTGGAGCCCTAATGTAGAAGAAGAAGAGTTACTGCGCCGCGATTGGGAAGAA
CTCATGGATCTGATTGTTTTGGGTAAAGTCGAAAGCATCACGGCTCGCCATGGTCAGGTGTTACAGTTGCGCCCCAAAGC
AGCCAATAGCCGGGCATTAACAGAAGCCATCGGTGAATTTGGGCAGCCTATCATGACCTTGCCACGTGGCTTTTATCTGA
AGAAGACACTGACCGCGCCGATGCTGGCTCGCCACTTTTTGCTGTAG

Upstream 100 bases:

>100_bases
AATCATGCTATTATTGCTGTCCGTTTCACTGGATTATAATGCTTGAGCGGTCATTTTTATTTGAGCTTATTTTTTAACCA
CTTTTAGCGAGTTTTTCCGA

Downstream 100 bases:

>100_bases
CCCAGTCATTCCGATTATGATCATTAATTCATTACACTAATTGATACGTTAATAATGATTAATACGGTAGTAGTGATTAA
TTAAAGCGGGATGTTCTCTA

Product: DNA mismatch repair protein

Products: NA

Alternate protein names: Methyl-directed mismatch repair protein [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSVYSLPPAPPSDEHQLFQRAQALSGFTLGELATRAQWVIPADLKRVKGWVGMLLEFYLGASAGSKPEQDFADIGIELKT
IPISAQGKPLETTFVCVAPLTGNSGVTWENSHVRHKLARVLWVPVEGERHIPLAERRVGAPLLWSPNVEEEELLRRDWEE
LMDLIVLGKVESITARHGQVLQLRPKAANSRALTEAIGEFGQPIMTLPRGFYLKKTLTAPMLARHFLL

Sequences:

>Translated_228_residues
MSVYSLPPAPPSDEHQLFQRAQALSGFTLGELATRAQWVIPADLKRVKGWVGMLLEFYLGASAGSKPEQDFADIGIELKT
IPISAQGKPLETTFVCVAPLTGNSGVTWENSHVRHKLARVLWVPVEGERHIPLAERRVGAPLLWSPNVEEEELLRRDWEE
LMDLIVLGKVESITARHGQVLQLRPKAANSRALTEAIGEFGQPIMTLPRGFYLKKTLTAPMLARHFLL
>Mature_227_residues
SVYSLPPAPPSDEHQLFQRAQALSGFTLGELATRAQWVIPADLKRVKGWVGMLLEFYLGASAGSKPEQDFADIGIELKTI
PISAQGKPLETTFVCVAPLTGNSGVTWENSHVRHKLARVLWVPVEGERHIPLAERRVGAPLLWSPNVEEEELLRRDWEEL
MDLIVLGKVESITARHGQVLQLRPKAANSRALTEAIGEFGQPIMTLPRGFYLKKTLTAPMLARHFLL

Specific function: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair [H]

COG id: COG3066

COG function: function code L; DNA mismatch repair protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mutH family [H]

Homologues:

Organism=Escherichia coli, GI1789196, Length=220, Percent_Identity=72.7272727272727, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004230
- InterPro:   IPR011337
- InterPro:   IPR011335 [H]

Pfam domain/function: PF02976 MutH [H]

EC number: NA

Molecular weight: Translated: 25360; Mature: 25229

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYSLPPAPPSDEHQLFQRAQALSGFTLGELATRAQWVIPADLKRVKGWVGMLLEFYLG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCEEECCHHHHHHHHHHHHHHHHHHC
ASAGSKPEQDFADIGIELKTIPISAQGKPLETTFVCVAPLTGNSGVTWENSHVRHKLARV
CCCCCCCCHHHHHCCEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHH
LWVPVEGERHIPLAERRVGAPLLWSPNVEEEELLRRDWEELMDLIVLGKVESITARHGQV
EEEECCCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
LQLRPKAANSRALTEAIGEFGQPIMTLPRGFYLKKTLTAPMLARHFLL
EEECCCCCCHHHHHHHHHHHCCCHHHCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVYSLPPAPPSDEHQLFQRAQALSGFTLGELATRAQWVIPADLKRVKGWVGMLLEFYLG
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCEEECCHHHHHHHHHHHHHHHHHHC
ASAGSKPEQDFADIGIELKTIPISAQGKPLETTFVCVAPLTGNSGVTWENSHVRHKLARV
CCCCCCCCHHHHHCCEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHH
LWVPVEGERHIPLAERRVGAPLLWSPNVEEEELLRRDWEELMDLIVLGKVESITARHGQV
EEEECCCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
LQLRPKAANSRALTEAIGEFGQPIMTLPRGFYLKKTLTAPMLARHFLL
EEECCCCCCHHHHHHHHHHHCCCHHHCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA