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The map label for this gene is fabZ

Identifier: 51597307

GI number: 51597307

Start: 3530012

End: 3530542

Strand: Reverse

Name: fabZ

Synonym: YPTB2992

Alternate gene names: 51597307

Gene position: 3530542-3530012 (Counterclockwise)

Preceding gene: 51597308

Following gene: 51597306

Centisome position: 74.41

GC content: 47.46

Gene sequence:

>531_bases
TTGACTACTGACACTCATACTCTGCATATTGAAGAGATTTTGGATCTACTCCCGCACCGTTTTCCGTTCTTGCTGGTAGA
CCGTGTCCTTGATTTTGAGGAAGGAAAATTTCTGCGTGCAGTGAAGAACGTCTCTTTTAACGAGCCATTTTTCCAAGGCC
ATTTCCCAGGCAAGCCCATCTTCCCTGGTGTGCTTATATTAGAAGCGATGGCGCAGGCTACAGGGATTTTGGCGTTTAAG
AGCCGCGGTAAACTGGAACCGGGCGAGCTTTATTACTTTGCTGGTATTGATGAAGCACGTTTTAAGCGCCCAGTAGTGCC
TGGCGATCAGATGATCATGGAAGTTGAGTTTGTTAAAGAACGCCGTGGCCTAACCCGTTTTACCGGTGTAGCTAAAGTCG
ATGGCGAAATCGTTTGCACTGCCACCATGATGTGCGCGCGTAGCAAACCAGCAGCACCTGCAGAATCTGTCGTTGTAAAA
CCAGATGTTGTAAAACCAGATGTTGTAAATCCTGTCGTTAAGGAGTCCTGA

Upstream 100 bases:

>100_bases
GTCTACAGAGTTCCTAATTTGCGGCCTGCCTAATGCCTCCCTTTGGGGCTGTGCAGGCCGTGTTGTTGATAGCATCAGTT
TTTTAGACAGGAAGAGTATT

Downstream 100 bases:

>100_bases
TTCGTGATTGACAAAACCGCCTTTATCCATCCAAGTTCTATCGTTGAAGAAGGTGCCATCATTGGCGCTGGTGTTTATAT
TGGGCCCTTCTGCATTGTCG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MTTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFK
SRGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKERRGLTRFTGVAKVDGEIVCTATMMCARSKPAAPAESVVVK
PDVVKPDVVNPVVKES

Sequences:

>Translated_176_residues
MTTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFK
SRGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKERRGLTRFTGVAKVDGEIVCTATMMCARSKPAAPAESVVVK
PDVVKPDVVNPVVKES
>Mature_175_residues
TTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKS
RGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKERRGLTRFTGVAKVDGEIVCTATMMCARSKPAAPAESVVVKP
DVVKPDVVNPVVKES

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=151, Percent_Identity=89.4039735099338, Blast_Score=277, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 19631; Mature: 19500

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPI
CCCCCCEEEHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLILEAMAQATGILAFKSRGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKE
CHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHH
RRGLTRFTGVAKVDGEIVCTATMMCARSKPAAPAESVVVKPDVVKPDVVNPVVKES
HCCCHHHCCEEECCCCEEEHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
TTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPI
CCCCCEEEHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLILEAMAQATGILAFKSRGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKE
CHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHH
RRGLTRFTGVAKVDGEIVCTATMMCARSKPAAPAESVVVKPDVVKPDVVNPVVKES
HCCCHHHCCEEECCCCEEEHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]