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The map label for this gene is proX

Identifier: 51597276

GI number: 51597276

Start: 3493843

End: 3494847

Strand: Direct

Name: proX

Synonym: YPTB2961

Alternate gene names: 51597276

Gene position: 3493843-3494847 (Clockwise)

Preceding gene: 51597275

Following gene: 51597278

Centisome position: 73.64

GC content: 48.76

Gene sequence:

>1005_bases
ATGCGCACGACAGGAATCTGGGCCTTGGCCCTCACCACACTGATCAGCTCTCAGTTATCCGCAGCAGAATTGCCGGGCAA
AGGTATCACCGTCCAGCCTCTGCAAAGCACCATTTCGGAAGAAACCTTCCAGACCTCGCTGGTCAATAAAGCGTTGGAAA
AACTCGGTTACGACGTCCAACCCACGAAAGAAGTCGATTACAATGTCGCCTACTCCTCCATTGCTGCAGGTGATGCAACC
TATCTGGCGGTAAATTGGGTGCCACTGCATAACGATCAATATAATGCAGCCGGTGGTGATGCTAAATTTTACCGGCAGGG
TAACTATATTGAAGGCTTGGCACAGGGTTATCTGATCGATAAAAAAACAGCCGACCAATACAACATCACCAATATTGCAC
AGTTAAAAGACCCGAAAATAGCCAAATTGTTTGATGCCAATAATGATGGCAAAGCCGATCTGACCGGCTGTAACCCCGGC
TGGGGTTGTGAGGCCCCAATTAACCATCAGATCAAAGCTTACGGCCTGAGCGATACGGTGACCCATAATCAGGGTAACTA
TGCCGCCATGATTGCCGATACCATTACCCGTTACAAAGAAGGCAAGCCCATTCTGTATTACACTTGGACGCCTTATTGGG
TCAGTGACGTATTGGTGCCGGGCCGTGATGTCGTGTGGCTACAAGTTCCCTTCTCTTCCTTGCCAGACAAAACTATCGAT
ACCCAGCTTTCTAATGGCGCGAACTATGGTTTCCCACCTAGCGTCATGCATATTGTGGCGAACAAAAAATGGGCTGAAGC
CAATCCGGCAGCCGCCAAGCTTTTCTCTATCATGAAATTATCTATTAATGATGTGAATGCTCAAAACATGCGGATGCACA
GTGGTGAATCCTCAGATGCCGATATTGAACGCCATGTAAATGGCTGGATCAACGCTCATCAGGCGACCTTCGATGGTTGG
GTAAAAACCGCGGCTGAAGCGGCTAATTCCCAAACGGCGCAGTAA

Upstream 100 bases:

>100_bases
ATACCACAGGGCCTGTTGGGTTGCTCACCAAACCCTTCTGTAACAGCAAATAATTTCAATTAATTACGCTCAAATAAAAT
AGCTTAAAAAAGGAAAAACT

Downstream 100 bases:

>100_bases
GTTAAGAGAAAACAGATACTTTCGGGTATCTGTGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAACAGGCAGATCGTA
AAGACGCCGTAAATACATCC

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRTTGIWALALTTLISSQLSAAELPGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQPTKEVDYNVAYSSIAAGDAT
YLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLIDKKTADQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPG
WGCEAPINHQIKAYGLSDTVTHNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDADIERHVNGWINAHQATFDGW
VKTAAEAANSQTAQ

Sequences:

>Translated_334_residues
MRTTGIWALALTTLISSQLSAAELPGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQPTKEVDYNVAYSSIAAGDAT
YLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLIDKKTADQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPG
WGCEAPINHQIKAYGLSDTVTHNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDADIERHVNGWINAHQATFDGW
VKTAAEAANSQTAQ
>Mature_334_residues
MRTTGIWALALTTLISSQLSAAELPGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQPTKEVDYNVAYSSIAAGDAT
YLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLIDKKTADQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPG
WGCEAPINHQIKAYGLSDTVTHNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDADIERHVNGWINAHQATFDGW
VKTAAEAANSQTAQ

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=328, Percent_Identity=71.9512195121951, Blast_Score=502, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 36556; Mature: 36556

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTGIWALALTTLISSQLSAAELPGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PTKEVDYNVAYSSIAAGDATYLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLID
CCCCCCCEEEEHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHCCEEEE
KKTADQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPGWGCEAPINHQIKAYGLSDTV
CCCCCCCCCCEEHHCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCE
THNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
ECCCCCEEEHHHHHHHHHHCCCCEEEEECCCHHHHHEECCCCCEEEEECCCCCCCCCHHH
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDA
HHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
DIERHVNGWINAHQATFDGWVKTAAEAANSQTAQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRTTGIWALALTTLISSQLSAAELPGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PTKEVDYNVAYSSIAAGDATYLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLID
CCCCCCCEEEEHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHCCEEEE
KKTADQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPGWGCEAPINHQIKAYGLSDTV
CCCCCCCCCCEEHHCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCE
THNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
ECCCCCEEEHHHHHHHHHHCCCCEEEEECCCHHHHHEECCCCCEEEEECCCCCCCCCHHH
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDA
HHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
DIERHVNGWINAHQATFDGWVKTAAEAANSQTAQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]