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The map label for this gene is pgm

Identifier: 51597239

GI number: 51597239

Start: 3456488

End: 3458173

Strand: Reverse

Name: pgm

Synonym: YPTB2923

Alternate gene names: 51597239

Gene position: 3458173-3456488 (Counterclockwise)

Preceding gene: 51597240

Following gene: 51597238

Centisome position: 72.89

GC content: 50.59

Gene sequence:

>1686_bases
ATGGCAACGCCCTTGCTGAGGACGTGTATAGGAGTAGTGACTGTGGCGAATCACCCTCGGGCTGGGCAACCTGCTCAGCA
AAGCGATTTAATTAACGTAGCTCAGTTGACATCGCAATATTATGTATTGCAGCCAGACCCTGAAGACCCCGCTCATGCCG
TTAAATTTGGTACTTCCGGCCACCGTGGTAGTTCAGTGCGCCACAGTTTTAATGAAGCTCATATTCTTGCTATCGCGCAG
GCGATAGCTGAAGTTCGTCATCAACACGGTATCAGCGGCCCATGCTATGTGGGTAAAGATACCCATGCGCTATCCGAGCC
CGCCTTTATTTCGGTGCTGGAAGTGTTGACGGCGAATGGTGTCGATGTTGTCGTACAGCAAGATAATGGTTTTACGCCAA
CACCGGCCATTTCCCATGTCATTCTTTGTCATAACGCCCAGGGTAAAGCGTTGGCGGATGGTATTGTCATTACGCCATCC
CACAACCCACCGGAAGACGGCGGCATTAAGTACAACCCGCCGAATGGTGGCCCAGCGGATACTAATCTGACGTCCGTGAT
TGAAAAGCGGGCTAATCAGTTACTCAGCCAGAATTTAAAGGGTGTTAAGCGCCAAACATTGGATAAAGCCTGGCAGAGCA
ATCATCTGCGTGAGCAGGATTTGCTCCAATCTTATGTTGAAGGTTTGGTGGATGTCGTTGATATTCCCGCCATTCAACAA
GCAGGGCTGAAGCTCGGTGTGGATCCGCTTGGCGGCTCCGGTATTGCCTACTGGCAGCGCATTGCTGAGTACTACAAGCT
GGATTTGACGTTGGTCAATAATGCCATCGATCAGACATTCCGATTTATGCATCTTGACCACGATGGTGTGATCCGCATGG
ATTGCTCTTCAGAGTCGGCGATGGCTGGTTTGTTGGCACTGCGCGATAAATTTGATTTAGCTTTTGCTAATGATCCAGAT
TACGACCGTCATGGCATTGTGACCCCAGCCGGGTTGATGAATCCGAATCATTATCTCGCGGTATCTATTAATTATCTGTT
CCAGCATCGCCCACAATGGGGGGCGGGGGGGGCAGTCGGTAAAACATTGGTTTCCAGTGCGATGATTGATCGGGTTGTGG
CTGATTTGGGCCGCAAGCTGGTGGAAGTCCCCGTTGGCTTTAAGTGGTTTGTTGATGGTTTACACGACGGCAGTTTTGGT
TTTGGTGGCGAAGAGAGTGCCGGGGCTTCTTTCCTGCGCTTTAATGGCACGCCGTGGTCGACCGATAAAGACGGCATTAT
CATGTGTCTGTTGGCGGCAGAAATTACGGCCGTGACCGGTAAGGATCCACAACGTCACTATGATGATTTAGCACAACGCT
TTGGTGCGCCAAGTTATAACCGTATTCAGGCGCCGGCAACGCAGGCGCAGAAAAATGCCTTGTCCAGATTGTCACCTGAA
ATGGTGAAAGCCAATACACTGGCGGGTGATCCGATCACTGCCCGTTTAACCAATGCCCCAGGGAATGGTGCATCAATTGG
TGGCTTGAAAGTGATGACTGAGAACGGCTGGTTTGCCGCTCGCCCATCAGGCACTGAAGAAGCGTACAAAATTTACTGTG
AAAGTTTCCTTGGCGCGGAGCATCGCGAAAAAATAGAACAAGAAGCCGTAAAGATTGTCAGCGAAGTGCTGGCTGAGGCG
AAATAA

Upstream 100 bases:

>100_bases
GGTACAGCACATCATGCTGGCAATGCAGTTCCCGCCGGAGTTGACTGACAAAGTGTGCGGAACTATCTGATTTCATTGAA
ACCATCCTCTTTCTCAGCCA

Downstream 100 bases:

>100_bases
GCGGGTATATTCCTGTCCTTAAAGACCAACGCTGTAATCTTGGCACTCGATCAATCCGGCACAGGCTCTGTTGCCGGATT
TTTTATGTGTTTTTCTTAAT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MATPLLRTCIGVVTVANHPRAGQPAQQSDLINVAQLTSQYYVLQPDPEDPAHAVKFGTSGHRGSSVRHSFNEAHILAIAQ
AIAEVRHQHGISGPCYVGKDTHALSEPAFISVLEVLTANGVDVVVQQDNGFTPTPAISHVILCHNAQGKALADGIVITPS
HNPPEDGGIKYNPPNGGPADTNLTSVIEKRANQLLSQNLKGVKRQTLDKAWQSNHLREQDLLQSYVEGLVDVVDIPAIQQ
AGLKLGVDPLGGSGIAYWQRIAEYYKLDLTLVNNAIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDKFDLAFANDPD
YDRHGIVTPAGLMNPNHYLAVSINYLFQHRPQWGAGGAVGKTLVSSAMIDRVVADLGRKLVEVPVGFKWFVDGLHDGSFG
FGGEESAGASFLRFNGTPWSTDKDGIIMCLLAAEITAVTGKDPQRHYDDLAQRFGAPSYNRIQAPATQAQKNALSRLSPE
MVKANTLAGDPITARLTNAPGNGASIGGLKVMTENGWFAARPSGTEEAYKIYCESFLGAEHREKIEQEAVKIVSEVLAEA
K

Sequences:

>Translated_561_residues
MATPLLRTCIGVVTVANHPRAGQPAQQSDLINVAQLTSQYYVLQPDPEDPAHAVKFGTSGHRGSSVRHSFNEAHILAIAQ
AIAEVRHQHGISGPCYVGKDTHALSEPAFISVLEVLTANGVDVVVQQDNGFTPTPAISHVILCHNAQGKALADGIVITPS
HNPPEDGGIKYNPPNGGPADTNLTSVIEKRANQLLSQNLKGVKRQTLDKAWQSNHLREQDLLQSYVEGLVDVVDIPAIQQ
AGLKLGVDPLGGSGIAYWQRIAEYYKLDLTLVNNAIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDKFDLAFANDPD
YDRHGIVTPAGLMNPNHYLAVSINYLFQHRPQWGAGGAVGKTLVSSAMIDRVVADLGRKLVEVPVGFKWFVDGLHDGSFG
FGGEESAGASFLRFNGTPWSTDKDGIIMCLLAAEITAVTGKDPQRHYDDLAQRFGAPSYNRIQAPATQAQKNALSRLSPE
MVKANTLAGDPITARLTNAPGNGASIGGLKVMTENGWFAARPSGTEEAYKIYCESFLGAEHREKIEQEAVKIVSEVLAEA
K
>Mature_560_residues
ATPLLRTCIGVVTVANHPRAGQPAQQSDLINVAQLTSQYYVLQPDPEDPAHAVKFGTSGHRGSSVRHSFNEAHILAIAQA
IAEVRHQHGISGPCYVGKDTHALSEPAFISVLEVLTANGVDVVVQQDNGFTPTPAISHVILCHNAQGKALADGIVITPSH
NPPEDGGIKYNPPNGGPADTNLTSVIEKRANQLLSQNLKGVKRQTLDKAWQSNHLREQDLLQSYVEGLVDVVDIPAIQQA
GLKLGVDPLGGSGIAYWQRIAEYYKLDLTLVNNAIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDKFDLAFANDPDY
DRHGIVTPAGLMNPNHYLAVSINYLFQHRPQWGAGGAVGKTLVSSAMIDRVVADLGRKLVEVPVGFKWFVDGLHDGSFGF
GGEESAGASFLRFNGTPWSTDKDGIIMCLLAAEITAVTGKDPQRHYDDLAQRFGAPSYNRIQAPATQAQKNALSRLSPEM
VKANTLAGDPITARLTNAPGNGASIGGLKVMTENGWFAARPSGTEEAYKIYCESFLGAEHREKIEQEAVKIVSEVLAEAK

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=447, Percent_Identity=25.9507829977629, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI21361621, Length=443, Percent_Identity=25.7336343115124, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI133922562, Length=402, Percent_Identity=25.3731343283582, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1786904, Length=546, Percent_Identity=82.2344322344322, Blast_Score=929, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=541, Percent_Identity=24.9537892791128, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322722, Length=555, Percent_Identity=26.8468468468468, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6323752, Length=566, Percent_Identity=23.8515901060071, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864244, Length=419, Percent_Identity=27.9236276849642, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 60500; Mature: 60369

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPLLRTCIGVVTVANHPRAGQPAQQSDLINVAQLTSQYYVLQPDPEDPAHAVKFGTSG
CCCHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCHHHEECCCCC
HRGSSVRHSFNEAHILAIAQAIAEVRHQHGISGPCYVGKDTHALSEPAFISVLEVLTANG
CCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCC
VDVVVQQDNGFTPTPAISHVILCHNAQGKALADGIVITPSHNPPEDGGIKYNPPNGGPAD
CEEEEECCCCCCCCHHHCEEEEEECCCCCEEECCEEECCCCCCCCCCCEEECCCCCCCCC
TNLTSVIEKRANQLLSQNLKGVKRQTLDKAWQSNHLREQDLLQSYVEGLVDVVDIPAIQQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
AGLKLGVDPLGGSGIAYWQRIAEYYKLDLTLVNNAIDQTFRFMHLDHDGVIRMDCSSESA
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCHH
MAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVSINYLFQHRPQWGAGGAVG
HHHHHHHHHCCCEEECCCCCCCCCCCCCCHHCCCCCCEEEEEEEEHHHCCCCCCCCCHHH
KTLVSSAMIDRVVADLGRKLVEVPVGFKWFVDGLHDGSFGFGGEESAGASFLRFNGTPWS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCCCCCCCCCCCCCCCEEEEECCCCCC
TDKDGIIMCLLAAEITAVTGKDPQRHYDDLAQRFGAPSYNRIQAPATQAQKNALSRLSPE
CCCCCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHH
MVKANTLAGDPITARLTNAPGNGASIGGLKVMTENGWFAARPSGTEEAYKIYCESFLGAE
HHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHCCH
HREKIEQEAVKIVSEVLAEAK
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATPLLRTCIGVVTVANHPRAGQPAQQSDLINVAQLTSQYYVLQPDPEDPAHAVKFGTSG
CCHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCHHHEECCCCC
HRGSSVRHSFNEAHILAIAQAIAEVRHQHGISGPCYVGKDTHALSEPAFISVLEVLTANG
CCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCC
VDVVVQQDNGFTPTPAISHVILCHNAQGKALADGIVITPSHNPPEDGGIKYNPPNGGPAD
CEEEEECCCCCCCCHHHCEEEEEECCCCCEEECCEEECCCCCCCCCCCEEECCCCCCCCC
TNLTSVIEKRANQLLSQNLKGVKRQTLDKAWQSNHLREQDLLQSYVEGLVDVVDIPAIQQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
AGLKLGVDPLGGSGIAYWQRIAEYYKLDLTLVNNAIDQTFRFMHLDHDGVIRMDCSSESA
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCHH
MAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVSINYLFQHRPQWGAGGAVG
HHHHHHHHHCCCEEECCCCCCCCCCCCCCHHCCCCCCEEEEEEEEHHHCCCCCCCCCHHH
KTLVSSAMIDRVVADLGRKLVEVPVGFKWFVDGLHDGSFGFGGEESAGASFLRFNGTPWS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCCCCCCCCCCCCCCCEEEEECCCCCC
TDKDGIIMCLLAAEITAVTGKDPQRHYDDLAQRFGAPSYNRIQAPATQAQKNALSRLSPE
CCCCCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHH
MVKANTLAGDPITARLTNAPGNGASIGGLKVMTENGWFAARPSGTEEAYKIYCESFLGAE
HHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHCCH
HREKIEQEAVKIVSEVLAEAK
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]