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The map label for this gene is pdxJ

Identifier: 51597203

GI number: 51597203

Start: 3417712

End: 3418443

Strand: Reverse

Name: pdxJ

Synonym: YPTB2887

Alternate gene names: 51597203

Gene position: 3418443-3417712 (Counterclockwise)

Preceding gene: 51597204

Following gene: 51597202

Centisome position: 72.05

GC content: 49.18

Gene sequence:

>732_bases
ATGGCTGATTTGTTGCTGGGCGTTAATATTGATCACATCGCGACACTACGAAATGCACGTGGGACCATTTATCCCGATCC
GGTTCAGGCTGCTTTTATTGCTGAGCAAGCGGGCGCTGACGGCATTACTGTACATTTACGTGAAGATCGCCGTCATATTA
CGGATCGCGATGTGCGTATTTTGCGTCAGACCATCCAGACTCGCATGAATCTGGAAATGGCGGTAACGGATGAAATGGTT
GATATTGCTTGTGATATCAAACCGCATTTTTGTTGTCTGGTACCTGAAAAACGTCAGGAAGTCACGACTGAAGGCGGGCT
AGATGTTGCCGGTCAGGTTGATAAAATGACCCTGGTGGTAGGGCGGTTAGCGGATGTTGGCATACTGGTTTCACTCTTTA
TTGATGCAGATTTTCGCCAAATCGATGCGGCTGTTGCCGCTGGCGCACCTTATATTGAAATTCACACCGGTGCTTATGCT
GATGCCTCGACCGTTCTGGAACGTCAGGCTGAATTAATGCGTATCGCCAAAGCAGCGACCTATGCTGCAGGCAAAGGGTT
GAAAGTGAATGCGGGTCATGGTCTGACATACCATAATGTGCAGCCAATAGCTGCATTGCCAGAAATGCATGAGCTGAATA
TTGGTCATGCGATCATTGGCCAGGCTGTGATGACAGGCCTTGCTACCGCAGTGACAGACATGAAGGTATTGATGCGGGAA
GCGCGCCGTTAA

Upstream 100 bases:

>100_bases
CTAGTCGGTGTAAACTGAAAATCACTGACGTGGTTATTGGTATGCTTTATTTATATGCTTATTAACCGATTAAAGATGCA
TCCATATTTGGAGGGCTGTC

Downstream 100 bases:

>100_bases
TGGCTATTCTTGGGCTAGGAACGGATATCGTTGAAATCTCACGTATTGAAGCGGTTGTTGAGCGTACTGGTGAGAGGCTG
GCGCGGCGTATTCTCAGCCC

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MADLLLGVNIDHIATLRNARGTIYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTIQTRMNLEMAVTDEMV
DIACDIKPHFCCLVPEKRQEVTTEGGLDVAGQVDKMTLVVGRLADVGILVSLFIDADFRQIDAAVAAGAPYIEIHTGAYA
DASTVLERQAELMRIAKAATYAAGKGLKVNAGHGLTYHNVQPIAALPEMHELNIGHAIIGQAVMTGLATAVTDMKVLMRE
ARR

Sequences:

>Translated_243_residues
MADLLLGVNIDHIATLRNARGTIYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTIQTRMNLEMAVTDEMV
DIACDIKPHFCCLVPEKRQEVTTEGGLDVAGQVDKMTLVVGRLADVGILVSLFIDADFRQIDAAVAAGAPYIEIHTGAYA
DASTVLERQAELMRIAKAATYAAGKGLKVNAGHGLTYHNVQPIAALPEMHELNIGHAIIGQAVMTGLATAVTDMKVLMRE
ARR
>Mature_242_residues
ADLLLGVNIDHIATLRNARGTIYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTIQTRMNLEMAVTDEMVD
IACDIKPHFCCLVPEKRQEVTTEGGLDVAGQVDKMTLVVGRLADVGILVSLFIDADFRQIDAAVAAGAPYIEIHTGAYAD
ASTVLERQAELMRIAKAATYAAGKGLKVNAGHGLTYHNVQPIAALPEMHELNIGHAIIGQAVMTGLATAVTDMKVLMREA
RR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=242, Percent_Identity=80.9917355371901, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 26356; Mature: 26225

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLLLGVNIDHIATLRNARGTIYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRI
CCCEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
LRQTIQTRMNLEMAVTDEMVDIACDIKPHFCCLVPEKRQEVTTEGGLDVAGQVDKMTLVV
HHHHHHHHHCCEEEEHHHHEEEEECCCCCEEEECCCHHHHHCCCCCCCCCCCHHHHHHHH
GRLADVGILVSLFIDADFRQIDAAVAAGAPYIEIHTGAYADASTVLERQAELMRIAKAAT
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
YAAGKGLKVNAGHGLTYHNVQPIAALPEMHELNIGHAIIGQAVMTGLATAVTDMKVLMRE
HHCCCCEEEECCCCCEECCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARR
HCC
>Mature Secondary Structure 
ADLLLGVNIDHIATLRNARGTIYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRI
CCEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
LRQTIQTRMNLEMAVTDEMVDIACDIKPHFCCLVPEKRQEVTTEGGLDVAGQVDKMTLVV
HHHHHHHHHCCEEEEHHHHEEEEECCCCCEEEECCCHHHHHCCCCCCCCCCCHHHHHHHH
GRLADVGILVSLFIDADFRQIDAAVAAGAPYIEIHTGAYADASTVLERQAELMRIAKAAT
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
YAAGKGLKVNAGHGLTYHNVQPIAALPEMHELNIGHAIIGQAVMTGLATAVTDMKVLMRE
HHCCCCEEEECCCCCEECCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARR
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]