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The map label for this gene is nifU

Identifier: 51597174

GI number: 51597174

Start: 3383972

End: 3384358

Strand: Reverse

Name: nifU

Synonym: YPTB2858

Alternate gene names: 51597174

Gene position: 3384358-3383972 (Counterclockwise)

Preceding gene: 51597175

Following gene: 51597173

Centisome position: 71.33

GC content: 47.03

Gene sequence:

>387_bases
ATGGCTTACAGCGAAAAAGTAATCGATCATTACGAAAATCCACGCAACGTGGGGTCGTTCGACAGTCAAGACCCTACTAT
CGGTAGTGGCATGGTTGGCGCACCCGCTTGTGGTGATGTCATGAAGTTGCAGATCAAAGTGAATGAAGCCGGTATTATTG
AAGACGCCCGCTTTAAGACTTATGGTTGCGGTTCTGCCATCGCCTCCAGCTCTTTAGTCACTGAATGGATGAAAGGCAAG
TCTCTCGAGCAGGCTGAAGCCATCAAAAATACTCAGATTGCTGAAGAACTGGAGTTACCGCCAGTCAAGATTCACTGCTC
AATTTTGGCAGAAGATGCTATTAAAGCCGCAATCGCCGACTACAAAAGCAAGCATACTGCCAAGTAA

Upstream 100 bases:

>100_bases
TTTATCCCCATTGTGGGATATGTTCAAGCAGGGCGTGGATATCAGCAGCATTGAATGGTCCCATCATTAATTCCACACTT
TAAGACTCAGGAGAAATCAC

Downstream 100 bases:

>100_bases
TTGTGATATGTGATTTTTATATCCAAGTGACTTCGAGATGCAGCTAACACTCGTGCATCTTGAAGGACGACAGGTATATA
TAGGTTATTAATAATTAGCT

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MAYSEKVIDHYENPRNVGSFDSQDPTIGSGMVGAPACGDVMKLQIKVNEAGIIEDARFKTYGCGSAIASSSLVTEWMKGK
SLEQAEAIKNTQIAEELELPPVKIHCSILAEDAIKAAIADYKSKHTAK

Sequences:

>Translated_128_residues
MAYSEKVIDHYENPRNVGSFDSQDPTIGSGMVGAPACGDVMKLQIKVNEAGIIEDARFKTYGCGSAIASSSLVTEWMKGK
SLEQAEAIKNTQIAEELELPPVKIHCSILAEDAIKAAIADYKSKHTAK
>Mature_127_residues
AYSEKVIDHYENPRNVGSFDSQDPTIGSGMVGAPACGDVMKLQIKVNEAGIIEDARFKTYGCGSAIASSSLVTEWMKGKS
LEQAEAIKNTQIAEELELPPVKIHCSILAEDAIKAAIADYKSKHTAK

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=126, Percent_Identity=72.2222222222222, Blast_Score=196, Evalue=3e-51,
Organism=Homo sapiens, GI24307953, Length=126, Percent_Identity=71.4285714285714, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1788878, Length=128, Percent_Identity=89.0625, Blast_Score=238, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17543474, Length=126, Percent_Identity=68.2539682539683, Blast_Score=192, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6325122, Length=124, Percent_Identity=68.5483870967742, Blast_Score=186, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6324800, Length=123, Percent_Identity=69.1056910569106, Blast_Score=181, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21355597, Length=126, Percent_Identity=72.2222222222222, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 13773; Mature: 13642

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSEKVIDHYENPRNVGSFDSQDPTIGSGMVGAPACGDVMKLQIKVNEAGIIEDARFKT
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCC
YGCGSAIASSSLVTEWMKGKSLEQAEAIKNTQIAEELELPPVKIHCSILAEDAIKAAIAD
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
YKSKHTAK
HHHCCCCC
>Mature Secondary Structure 
AYSEKVIDHYENPRNVGSFDSQDPTIGSGMVGAPACGDVMKLQIKVNEAGIIEDARFKT
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCC
YGCGSAIASSSLVTEWMKGKSLEQAEAIKNTQIAEELELPPVKIHCSILAEDAIKAAIAD
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
YKSKHTAK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]