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The map label for this gene is xseA

Identifier: 51597150

GI number: 51597150

Start: 3348401

End: 3349780

Strand: Direct

Name: xseA

Synonym: YPTB2834

Alternate gene names: 51597150

Gene position: 3348401-3349780 (Clockwise)

Preceding gene: 51597147

Following gene: 51597163

Centisome position: 70.57

GC content: 52.17

Gene sequence:

>1380_bases
ATGTCGCAATCTTCCGCCTCCTCAATTTTTACTGTCAGCCGCCTGAATCAGACGGTACGAGAACTATTGGAAAGGGAAAT
GGGCCAGATTTGGCTCACTGCCGAGATTTCTAATTTCTCTCAGCCCGCTTCTGGGCACTGGTATTTCACGCTGAAAGATG
ATCGGGCGCAAGTGCGCTGTGCCATGTTTCGTAACAGCAACCGCCGCACCACTTTCCGTCCGCAGAATGGCCAACAAGTT
TTGGTCAGGGCATCAATTACCCTGTATGAACCCCGTGGTGATTATCAGTTAATTGCGGAAAGTATGCAGCCTGCCGGTGA
TGGGTTGCTGCAACAACAATTTGAACAGCTTAAGCAACAATTAGCGGCCGAAGGGCTGTTTGATCAAAGCCACAAACAGC
CACTCCCTAGCCCCGCCAAACAAGTGGGCGTAATAACGTCTGCCAGTGGGGCTGCGCTGCATGATGTGCTGCATGTGTTA
CAGCGCCGTGATCCATCGCTTCCAGTAATTATTTATCCCACATCAGTACAGGGCGTTGATGCGCCATTGCAGATAGTCCG
TGCGATCCAGTTGGCGAACTTACGTGCTGAATGCGATGTATTGATTGTTGGCCGCGGTGGCGGATCGCTAGAAGATTTGT
GGAGTTTCAACGACGAACGGGTTGCCCGCGCTATCTTTAACAGCCATATCCCTATCGTCAGCGCTGTCGGCCATGAAACC
GATGTCACTATTGCCGATTTTGTTGCTGATTTACGCGCCCCAACCCCTTCGGCTGCCGCCGAGCTAGTCAGTCGCAATCA
GATTGAGCTCGTTCGTCAGATTCAAGGGCAACAGCAACGAATGGAAATGGCGATGGATTACTATCTGGCGCAACGCAACC
AGCAATTCACCCGCCTTGAACACCGTTTGCAGCAACAGCATCCGCATTTACGTTTAGCCCGTCAGCAAACATTGTTGCTG
AAATTACAACGTAGGCTGGAAGAGAGTGCACAAACACAGATCCGCTTATTAAGTAAACGTACCGAGCGACTGCAACAGCG
TTTGCAGCAAGTGCAGCCTCAGGGGCAAATTCACCGGTATAACCAGCGGGTACAGCAGCAAGAATACCGTTTACGTCAAG
CTGTAGAGCGCCAGCTCAATGGCTATCGCCAACGCTTTGGTATCGCCTGCTCCCAGCTAGAGGCCGTGAGCCCACTGGCA
ACACTGGCCCGTGGCTACAGCGTGACACAGACGCCAGCAGGGGCGTTATTGAAGACCACCAAGCAAGTACAGGCCGGTGA
TAAACTGACCACCCGGTTGCAAGACGGTTGGGTGGAAAGTGAGATTACCCAAGTCACCGTAGCGAAGAAAAGCCGTCAGA
AAAAAGTAGTGACGCAGTGA

Upstream 100 bases:

>100_bases
GATTGCCTCCAGCACTTTCTCATAATATTTCTTGCCAACCAGTTTGAGGCAGGTAATATCGGTTAATTAAGTCCTTGTTT
TAAAATTTGATCCAGGTCAC

Downstream 100 bases:

>100_bases
CGCAGTGACGCAGTGACGCAGTGACGCAGTGACGCAGTGACGCAGTGACGCAGTGACGCAGTGACGCAGTGACGCAGTGA
CGCAGTGATTATAGCGGCAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQV
LVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPSPAKQVGVITSASGAALHDVLHVL
QRRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLL
KLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLA
TLARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ

Sequences:

>Translated_459_residues
MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQV
LVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPSPAKQVGVITSASGAALHDVLHVL
QRRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLL
KLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLA
TLARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ
>Mature_458_residues
SQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQVL
VRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPSPAKQVGVITSASGAALHDVLHVLQ
RRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHETD
VTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLLK
LQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLAT
LARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=454, Percent_Identity=72.0264317180617, Blast_Score=670, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 52049; Mature: 51918

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRC
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEEECCCHHHHH
AMFRNSNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQ
HHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LAAEGLFDQSHKQPLPSPAKQVGVITSASGAALHDVLHVLQRRDPSLPVIIYPTSVQGVD
HHHHCCCCCCCCCCCCCHHHHHCEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCC
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLE
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HRLQQQHPHLRLARQQTLLLKLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPAGALLKTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ
HHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRC
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEEECCCHHHHH
AMFRNSNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQ
HHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LAAEGLFDQSHKQPLPSPAKQVGVITSASGAALHDVLHVLQRRDPSLPVIIYPTSVQGVD
HHHHCCCCCCCCCCCCCHHHHHCEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCC
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLE
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HRLQQQHPHLRLARQQTLLLKLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPAGALLKTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ
HHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA